Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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Allan McRae Email
Telephone: +61 7 3362 0190
Facsimile: +61 7 3362 0101
Email: allanM@qimrberghofer.edu.au

I do not maintain this page. Please vist my external website for information on my research.


Below are some of the publications Dr McRae has co-authored with other research staff at GenEpi. For a complete list of publications please visit his external website.

Publications
2015
 McRae AF, Visscher PM, Montgomery GW, Martin NG: Large Autosomal Copy-Number Differences within Unselected Monozygotic Twin Pairs are Rare. Twin Research and Human Genetics 18(1):13-18, 2015 [PDF] [PubMed] [More...]
 Marioni RE, Shah S, McRae AF, Chen BH, Colicino E, Harris SE, Gibson J, Henders AK, Redmond P, Cox SR, Pattie A, Corley J, Murphy L, Martin NG, Montgomery GW, Feinberg AP, Fallin MD, Multhaup ML, Jaffe AE, Joehanes R, Schwartz J, Just AC, Lunetta KL, Murabito JM, Starr JM, Horvath S, Baccarelli AA, Levy D, Visscher PM, Wray NR, Deary IJ: DNA methylation age of blood predicts all-cause mortality in later life. Genome biology 16:25: 2015 [PDF] [N/OSI] [PubMed] [More...]
2014
 Hemani G, Shakhbazov K, Westra HJ, Esko T, Henders AK, McRae AF, Yang J, Gibson G, Martin NG, Metspalu A, Franke L, Montgomery GW, Visscher PM, Powell JE: Detection and replication of epistasis influencing transcription in humans. Nature 508(7495):249-253, 2014 [PDF] [PubMed] [More...]
 McRae AF, Powell JE, Henders AK, Bowdler L, Hemani G, Shah S, Painter JN, Martin NG, Visscher PM, Montgomery GW: Contribution of genetic variation to transgenerational inheritance of DNA methylation. Genome biology 15(5):R73, 2014 [PDF] [PubMed] [More...]
 Shah S, McRae AF, Marioni RE, Harris SE, Gibson J, Henders AK, Redmond P, Cox SR, Pattie A, Corley J, Murphy L, Martin NG, Montgomery GW, Starr JM, Wray NR, Deary IJ, Visscher PM: Genetic and environmental exposures constrain epigenetic drift over the human life course. Genome Research 24(11):1725-1733, 2014 [PDF] [OSI] [PubMed] [More...]
2013
 McRae AF, Wright MJ, Hansell NK, Montgomery GW, Martin NG: No Association Between General Cognitive Ability and Rare Copy Number Variation. Behavior Genetics 43(3):202-207, 2013 [PDF] [N/OSI] [PubMed] [More...]
 Powell JE, Henders AK, McRae AF, Kim J, Hemani G, Martin NG, Dermitzakis ET, Gibson G, Montgomery GW, Visscher PM: Congruence of additive and non-additive effects on gene expression estimated from pedigree and SNP data. PLoS Genetics 9(5):e1003502, 2013 [PDF] [OSI] [PubMed] [More...]
 Byrne EM, Carrillo-Roa T, Henders AK, Bowdler L, McRae AF, Heath AC, Martin NG, Montgomery GW, Krause L, Wray NR: Monozygotic twins affected with major depressive disorder have greater variance in methylation than their unaffected co-twin. Translational Psychiatry 3:e269, 2013 [PDF] [OSI] [PubMed] [More...]
 McRae AF, Richter MM, Lind PA: Case-control association testing of common variants from sequencing of DNA pools. PLoS ONE 8(6):e65410, 2013 [PDF unavailable] [PubMed] [More...]
 Goldinger A, Henders AK, McRae AF, Martin NG, Gibson G, Montgomery GW, Visscher PM, Powell JE: Genetic and Non-Genetic Variation Revealed for the Principal Components of Human Gene Expression. Genetics 195(3):1117-1128, 2013 [PDF] [OSI] [PubMed] [More...]
2012
 Powell JE, Henders AK, McRae AF, Wright MJ, Martin NG, Dermitzakis ET, Montgomery GW, Visscher PM: Genetic control of gene expression in whole blood and lymphoblastoid cell lines is largely independent. Genome Research 22(3):456-466, 2012 [PDF] [OSI] [PubMed] [More...]
 Mosing MA, Medland SE, McRae A, Landers JG, Wright MJ, Martin NG: Genetic Influences on Life Span and Its Relationship to Personality: A 16-Year Follow-Up Study of a Sample of Aging Twins. Psychosomatic Medicine 74(1):16-22, 2012 [PDF] [N/OSI] [PubMed] [More...]
 Powell JE, Henders AK, McRae AF, Caracella A, Smith S, Wright MJ, Whitfield JB, Dermitzakis ET, Martin NG, Visscher PM, Montgomery GW: The Brisbane Systems Genetics Study: Genetical genomics meets complex trait genetics. PLoS ONE 7(4):e35430, 2012 [PDF] [OSI] [PubMed] [More...]
 Byrne EM, Johnson J, McRae AF, Nyholt DR, Medland SE, Gehrman PR, Heath AC, Madden PA, Montgomery GW, Chenevix-Trench G, Martin NG: A genome-wide association study of caffeine-related sleep disturbance: confirmation of a role for a common variant in the adenosine receptor. Sleep 35(7):967-975, 2012 [PDF] [N/OSI] [PubMed] [More...]
2011
 Ferreira MA, McRae AF, Medland SE, Nyholt DR, Gordon SD, Wright MJ, Henders AK, Madden PA, Visscher PM, Wray NR, Heath AC, Montgomery GW, Duffy DL, Martin NG: Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia. European Journal of Human Genetics 19:458-464, 2011 [PDF] [PubMed] [More...]
 Frank RA, McRae AF, Pocklington AJ, van de Lagemaat LN, Navarro P, Croning MD, Komiyama NH, Bradley SJ, Challiss RA, Armstrong JD, Finn RD, Malloy MP, MacLean AW, Harris SE, Starr JM, Bhaskar SS, Howard EK, Hunt SE, Coffey AJ, Ranganath V, Deloukas P, Rogers J, Muir WJ, Deary IJ, Blackwood DH, Visscher PM, Grant SG: Clustered coding variants in the glutamate receptor complexes of individuals with schizophrenia and bipolar disorder. PLoS ONE 6(4):e19011, 2011 [PDF unavailable] [PubMed] [More...]
 Larsson M, Duffy DL, Zhu G, Liu JZ, Macgregor S, McRae AF, Wright MJ, Sturm RA, Mackey DA, Montgomery GW, Martin NG, Medland SE: GWAS Findings for Human Iris Patterns: Associations with Variants in Genes that Influence Normal Neuronal Pattern Development. American Journal of Human Genetics 89(2):334-343, 2011 [PDF] [OSI] [PubMed] [More...]
 Luong HT, Chaplin J, McRae AF, Medland SE, Willemsen G, Nyholt DR, Henders AK, Hoekstra C, Duffy DL, Martin NG, Boomsma DI, Montgomery GW, Painter JN: Variation in BMPR1B, TGFRB1 and BMPR2 and Control of Dizygotic Twinning. Twin Research and Human Genetics 14(5):408-416, 2011 [PDF] [PubMed] [More...]
2010
 Liu JZ, Medland SE, Wright MJ, Henders AK, Heath AC, Madden PA, Duncan A, Montgomery GW, Martin NG, McRae AF: Genome-wide association study of height and body mass index in Australian twin families. Twin Research and Human Genetics 13(2):179-193, 2010 [PDF] [PubMed] [More...]
 Gratten J, Wilson AJ, McRae AF, Beraldi D, Visscher PM, Pemberton JM, Slate J: No evidence for warming climate theory of coat colour change in Soay sheep: a comment on Maloney et al. Biology Letters 6:678-679, 2010 [PDF unavailable] [PubMed] [More...]
 Liu JZ, McRae AF, Nyholt DR, Medland SE, Wray NR, Brown KM, AMFS Investigators, Hayward NK, Montgomery GW, Visscher PM, Martin NG, Macgregor S: A versatile gene-based test for genome-wide association studies. American Journal of Human Genetics 87(1):139-145, 2010 [PDF] [PubMed] [More...]
2009
 Benyamin B, McRae AF, Zhu G, Gordon S, Henders AK, Palotie A, Peltonen L, Martin NG, Montgomery GW, Whitfield JB, Visscher PM: Variants in TF and HFE Explain approximately 40% of Genetic Variation in Serum-Transferrin Levels. American Journal of Human Genetics 84:60-65, 2009 [PDF] [PubMed] [More...]
 Kaminsky ZA, Tang T, Wang SC, Ptak C, Oh GH, Wong AH, Feldcamp LA, Virtanen C, Halfvarson J, Tysk C, McRae AF, Visscher PM, Montgomery GW, Gottesman II, Martin NG, Petronis A: DNA methylation profiles in monozygotic and dizygotic twins. Nature Genetics 41(2):240-245, 2009 [PDF] [PubMed] [More...]
 Benyamin B, Visscher PM, McRae AF: Family-based genome-wide association studies. Pharmacogenomics 10(2):181-190, 2009 [PDF] [PubMed] [More...]
 McEvoy BP, Montgomery GW, McRae AF, Ripatti S, Perola M, Spector TD, Cherkas L, Ahmadi KR, Boomsma D, Willemsen G, Hottenga JJ, Pedersen NL, Magnusson PK, Kyvik KO, Christensen K, Kaprio J, Heikkilä K, Palotie A, Widen E, Muilu J, Syvänen AC, Liljedahl U, Hardiman O, Cronin S, Peltonen L, Martin NG, Visscher PM: Geographical structure and differential natural selection among North European populations. Genome Research 19:804-814, 2009 [PDF] [PubMed] [More...]
 Byrne EM, McRae AF, Duffy DL, Zhao ZZ, Martin NG, Wright MJ, Montgomery GW, Visscher PM: Association Study of Common Mitochondrial Variants and Cognitive Ability. Behavior Genetics 39:504-512, 2009 [PDF] [PubMed] [More...]
 Keller MC, McRae AF, McGaughran JM, Visscher PM, Martin NG, Montgomery GW: Non-pathological paternal isodisomy of chromosome 2 detected from a genome-wide SNP scan. American journal of medical genetics. Part A 149A(8):1823-1826, 2009 [PDF] [PubMed] [More...]
 Byrne EM, McRae AF, Duffy DL, Zhao ZZ, Martin NG, Whitfield JB, Visscher PM, Montgomery GW: Family-based mitochondrial association study of traits related to type 2 diabetes and the metabolic syndrome in adolescents. Diabetologia 52(11):2359-2368, 2009 [PDF] [PubMed] [More...]
 Medland SE, Nyholt DR, Painter JN, McEvoy BP, McRae AF, Zhu G, Gordon SD, Ferreira MA, Wright MJ, Henders AK, Campbell MJ, Duffy DL, Hansell NK, Macgregor S, Slutske WS, Heath AC, Montgomery GW, Martin NG: Common Variants in the Trichohyalin Gene Are Associated with Straight Hair in Europeans. American Journal of Human Genetics 85:750-755, 2009 [PDF] [OSI] [PubMed] [More...]
 Knight HM, Pickard BS, Maclean A, Malloy MP, Soares DC, McRae AF, Condie A, White A, Hawkins W, McGhee K, van Beck M, MacIntyre DJ, Starr JM, Deary IJ, Visscher PM, Porteous DJ, Cannon RE, St Clair D, Muir WJ, Blackwood DH: A Cytogenetic Abnormality and Rare Coding Variants Identify ABCA13 as a Candidate Gene in Schizophrenia, Bipolar Disorder, and Depression. American Journal of Human Genetics 85:833-846, 2009 [PDF] [PubMed] [More...]
 Johnston SE, Beraldi D, McRae AF, Pemberton JM, Slate J: Horn type and horn length genes map to the same chromosomal region in Soay sheep. Heredity 2009 [PDF unavailable] [PubMed] [More...]
2008
 Gratten J, Wilson AJ, McRae AF, Beraldi D, Visscher PM, Pemberton JM, Slate J: A localized negative genetic correlation constrains microevolution of coat color in wild sheep. Science 319(5861):318-320, 2008 [PDF] [PubMed] [More...]
 McRae AF, Byrne EM, Zhao ZZ, Montgomery GW, Visscher PM: Power and SNP Tagging in Whole Mitochondrial Genome Association Studies. Genome Research 18:911-917, 2008 [PDF] [PubMed] [More...]
 Keith JM, McRae A, Duffy D, Mengersen K, Visscher PM: Calculation of IBD probabilities with dense SNP or sequence data. Genetic Epidemiology (epub 20/03/2008) 2008 [PDF unavailable] [PubMed] [More...]
 Byrne EM, McRae AF, Zhao ZZ, Martin NG, Montgomery GW, Visscher PM: The use of common mitochondrial variants to detect and characterise population structure in the Australian population: implications for genome-wide association studies. European Journal of Human Genetics 16(11):1396-1403, 2008 [PDF] [PubMed] [More...]
 Middelberg RP, Gordon SD, Zhu G, McRae A, Montgomery GW, Martin NG, Whitfield JB: Linkage and association analyses of longitudinally measured lipid phenotypes in adolescence. Twin Research and Human Genetics 11(6):603-620, 2008 [PDF] [PubMed] [More...]
 Sved JA, McRae AF, Visscher PM: Divergence between human populations estimated from linkage disequilibrium. American Journal of Human Genetics 83(6):737-743, 2008 [PDF unavailable] [PubMed] [More...]
2007
 Beraldi D, McRae AF, Gratten J, Pilkington JG, Slate J, Visscher PM, Pemberton JM: Quantitative trait loci (QTL) mapping of resistance to strongyles and coccidia in the free-living Soay sheep (Ovis aries). International Journal for Parasitology 37(1):121-129, 2007 [PDF] [PubMed] [More...]
 Gratten J, Beraldi D, Lowder BV, McRae AF, Visscher PM, Pemberton JM, Slate J: Compelling evidence that a single nucleotide substitution in TYRP1 is responsible for coat-colour polymorphism in a free-living population of Soay sheep. Proceedings of the Royal Society B: Biological Sciences 274(1610):619-626, 2007 [PDF] [PubMed] [More...]
 Beraldi D, McRae AF, Gratten J, Slate J, Visscher PM, Pemberton JM: Mapping quantitative trait Loci underlying fitness-related traits in a free-living sheep population. Evolution 61(6):1403-1416, 2007 [PDF] [PubMed] [More...]
 McRae AF, Matigian NA, Vadlamudi L, Mulley JC, Mowry B, Martin NG, Berkovic SF, Hayward NK, Visscher PM: Replicated effects of sex and genotype on gene expression in human lymphoblastoid cell lines. Human Molecular Genetics 16(4):364-373, 2007 [PDF] [PubMed] [More...]
2006
 Beraldi D, McRae AF, Gratten J, Slate J, Visscher PM, Pemberton JM: Development of a Linkage Map and Mapping of Phenotypic Polymorphisms in a Free-living Population of Soay Sheep (Ovis aries). Genetics 173(3):1521-1537, 2006 [PDF] [PubMed] [More...]
 Anderson CA, McRae AF, Visscher PM: A simple linear regression method for quantitative trait loci linkage analysis with censored observations. Genetics 173(3):1735-1745, 2006 [PDF] [PubMed] [More...]
 McRae AF, Beraldi D: Examination of a region showing linkage map discrepancies across sheep breeds. Mammalian Genome 17(4):346-353, 2006 [PDF unavailable] [PubMed] [More...]
2005
 McRae AF, Bishop SC, Walling GA, Wilson AD, Visscher PM: Mapping of Multiple Quantitative Trait Loci for Growth and Carcass Traits in a Complex Commercial Sheep Pedigree. Animal Science 80:135-141, 2005 [PDF]
 McRae AF, Pemberton JM, Visscher PM: Modeling linkage disequilibrium in natural populations: the example of the Soay sheep population of St. Kilda, Scotland. Genetics 171(1):251-258, 2005 [PDF] [PubMed] [More...]
2003
 Campbell AW, Bain WE, McRae AF, Broad TE, Johnstone PD, Dodds KG, Veenvliet BA, Greer GJ, Glass BC, Beattie AE, Jopson NB, McEwan JC: Bone density in sheep: genetic variation and quantitative trait loci localisation. Bone 33(4):540-548, 2003 [PDF unavailable] [PubMed] [More...]
2002
 McRae AF, McEwan JC, Dodds KG, Wilson T, Crawford AM, Slate J: Linkage disequilibrium in domestic sheep. Genetics 160(3):1113-1122, 2002 [PDF unavailable] [PubMed] [More...]
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