!
! Boehnke M, Langefeld CD (1998): Genetic association mapping based on 
!    discordant sib pairs: the discordant-alleles test.  Am J Hum Genet 
!    62: 950-961.
!
! Table 5.  ApoE genotypes and allele counts and statistics for 
! the Alzheimer Disease DSPs.
!
! Aff         UnA Sib
! Sib   2/2 2/3 2/4 3/3 3/4 4/4    The permutation tests described by the
!     +------------------------    authors obtained P-values of 1e-8 to
! 2/2 | 0   0   0   0   0   0      3.7e-6 for allelic or genotypic test
! 2/3 | 0   0   0   0   0   0      
! 2/4 | 0   0   1   0   0   0
! 3/3 | 0   1   0   22  4   0
! 3/4 | 0   2   1   23  34  2
! 4/4 | 0   2   1   6   7   6
!
set data ../pedigrees
set loc AD aff
set loc APOE marker
read pedigree dsp.ped
run
set ple 2
assoc AD
