!
! Idiopathic generalized epilepsy -- Zara et al (Hum Mol Genet 1995; 4:1201-7)
! Used by Kruglyak & Lander (AJHG 1996 58:1347-63): individuals numbered 
! as per their Figure 7 
!
! 3 trimmed versions of pedigree 5
!        Complete pedigree                     Most trimmed pedigree
! 
!        1               2                       1               2
!       4/9             2/5                     4/9             2/5
!        |               |                       |               |
!        +------+--------+                       +-------+-------+
!               |                                        |
!    +----------+--+-------------+                       +--+-------------+
!    |             |             |                          |             |
!  *12*    4      *3*    6      *5*                 4      *3*           *5*
!   x/x   1/8     4/5   6/x     4/5                1/8     4/5           4/5
!          |       |     |       |                  |       |              
!          +---+---+     +---+---+                  +---+---+              
!              |             |                          |
!          +---+---+         |                      +---+---+
!          |       |         |                      |       |
!  *10*    8      *9*        7                      8      *9*
!   x/x   1/5     5/8       5/6                    1/5     5/8
!    |     |
!    +--+--+
!       |
!     *11*
!      x/x
!
! Genehunter gives exactly the same NPL score for each form: 1.2649
!
!                                        Sib-pair gives (for the same forms)
! and uses in the first case: 3 5 9 8 7     0.838
!            the second case: 3 5 9 8       1.021
!             the third case: 3 5 9 8       1.305
!
!
!
set workdir /tmp/
set iter 1000
set wei founders
set locus epilepsy aff
set locus D8S284 mar
set locus D8S256 mar
set locus D8S534 mar
read pedigree epil5.ped
run
set plevel 1
keep epilepsy D8S256
apm epilepsy ibd
! write locus linkage e5.loc
! write linkage e5.pre

