! ! Pedigrees from Keavney et al ! Measured haplotype analysis of the angiotensin-I converting enzyme gene ! Hum Mol Genet 1998 7: 1745-1751 ! ! as included in MENDEL 4 example pedigree files: ACE I/D polymorphism and ! sex-standardised sACE. ! set loc aceins mar . The ACE Insertion/Deletion Polymorphism set loc sace qua . Sex-standardized sACE level read ped inline 1 1 x x M 1 2 -0.395 1 2 x x F 1 2 -1.788 1 3 1 2 M 1 1 -0.873 1 4 x x M 1 2 -0.477 1 5 1 2 F 1 2 -0.897 1 6 1 2 F 1 2 -0.486 1 7 1 2 F 1 2 -0.52 1 8 1 2 F 1 2 -0.863 1 9 4 5 F 1 2 0.337 1 10 4 5 F 1 1 -1.308 2 1 x x M x x x 2 2 x x F x x x 2 3 x x M 2 2 -0.527 2 4 1 2 F 2 2 0.337 2 5 3 4 M 2 2 1.187 2 6 3 4 F 2 2 1.639 3 1 x x M x x x 3 2 x x F x x x 3 3 1 2 M 2 2 x 3 4 x x F 2 2 0.131 3 5 1 2 M 1 2 -0.708 3 6 x x F 2 2 x 3 7 1 2 M 1 2 -2.109 3 8 x x M 1 1 -0.741 3 9 1 2 F 1 2 -0.452 3 10 3 4 F 2 2 1.073 3 11 3 4 F 2 2 0.199 3 12 3 4 F 2 2 1.776 3 13 3 4 M 2 2 1.006 3 14 5 6 M 2 2 2.686 3 15 5 6 F 1 2 -0.572 3 16 8 9 M 1 1 -0.296 3 17 8 9 M x x x 3 18 8 9 M 1 2 0.561 4 1 x x M x x x 4 2 x x F x x x 4 3 x x M 2 2 0.577 4 4 1 2 F 1 2 x 4 5 1 2 M 2 2 0.791 4 6 3 4 F 1 2 1.090 4 7 3 4 F 2 2 2.067 4 8 3 4 M 1 2 0.857 5 1 x x M x x x 5 2 x x F x x x 5 3 1 2 M 1 1 -1.367 5 4 1 2 F 1 2 0.217 5 5 1 2 F 1 1 x 5 6 1 2 F x x -1.188 5 7 1 2 M 1 2 -0.955 5 8 1 2 F 1 1 -0.983 5 9 x x M 1 2 0.511 5 10 1 2 M 1 2 x 5 11 x x F 1 2 -1.257 5 12 1 2 M 1 2 -0.461 5 13 1 2 M 1 2 -0.593 5 14 1 2 M 1 1 -1.977 5 15 1 2 M 1 2 -0.939 5 16 9 8 M 1 2 0.099 5 17 10 11 M 2 2 -0.329 5 18 10 11 M 1 2 -0.065 6 1 x x M x x x 6 2 x x F x x x 6 3 1 2 F 1 2 -0.486 6 4 1 2 M 1 2 x 6 5 1 2 F 1 2 x 6 6 x x M 2 2 2.011 6 7 1 2 M x x -0.642 6 8 1 2 M 1 2 x 6 9 6 5 M 1 2 0.462 6 10 6 5 F 2 2 -0.023 7 1 x x M 1 2 -0.197 7 2 x x F x x x 7 3 1 2 F 1 2 -0.160 7 4 1 2 M 1 2 1.137 7 5 x x F 1 1 -0.572 7 6 1 2 M 1 2 x 7 7 1 2 M 2 2 1.895 7 8 6 5 M 1 1 -0.313 7 9 6 5 M 1 1 -0.214 7 10 6 5 F 1 1 -0.949 8 1 x x M x x x 8 2 x x F 1 2 -1.240 8 3 x x F 1 1 -1.017 8 4 1 2 M 1 1 -1.927 8 5 1 2 M 1 2 -0.560 8 6 x x F 1 2 -0.126 8 7 4 3 F 1 1 -1.240 8 8 4 3 F 1 1 -1.514 8 9 4 3 M 1 1 -1.499 8 10 4 3 F 1 1 -1.394 8 11 5 6 M 1 1 -1.021 8 12 5 6 M 2 2 0.940 9 1 x x M x x x 9 2 x x F x x x 9 3 1 2 M 2 2 x 9 4 x x F x x -0.606 9 5 1 2 M 1 2 x 9 6 1 2 F 1 2 -1.480 9 7 x x M x x x 9 8 1 2 F 2 2 -0.332 9 9 1 2 F 1 2 1.005 9 10 7 8 M 1 2 -0.082 9 11 7 8 F 1 2 -0.212 9 12 7 8 F 1 2 -0.657 9 13 5 4 M x x x 10 1 x x M 2 2 1.862 10 2 x x F 2 2 -0.640 10 3 1 2 F 2 2 0.679 10 4 1 2 M 2 2 1.401 10 5 1 2 F 2 2 1.467 11 1 x x M 1 1 x 11 2 x x F x x x 11 3 1 2 F 1 2 0.268 11 4 1 2 M 1 2 1.039 11 5 x x F 2 2 0.611 11 6 1 2 F 1 1 -1.428 11 7 4 5 F 1 2 0.199 11 8 4 5 F 1 2 0.405 11 9 4 5 F 2 2 2.256 12 1 x x M 1 1 -0.593 12 2 x x F 2 2 1.587 12 3 1 2 F 1 2 -0.537 12 4 1 2 F 1 2 -0.589 12 5 1 2 M 1 2 0.215 12 6 1 2 F 1 2 0.782 12 7 1 2 M 1 2 0.890 12 8 1 2 F 1 2 0.131 13 1 x x M x x x 13 2 x x F x x x 13 3 1 2 F 1 1 -0.709 13 4 x x M 2 2 0.775 13 5 1 2 F 1 1 x 13 6 1 2 F 1 1 -0.674 13 7 1 2 F 1 1 -0.469 13 8 4 5 F 1 2 -0.040 13 9 4 5 F 1 2 0.302 13 10 4 5 F 1 2 -0.435 13 11 4 5 F 1 2 1.228 14 1 x x M 1 2 0.099 14 2 x x F x x x 14 3 1 2 M 1 2 x 14 4 1 2 F 1 2 -0.229 14 5 1 2 F 2 2 0.354 14 6 1 2 M 2 2 1.632 15 1 x x M 1 2 0.198 15 2 x x F 2 2 2.084 15 3 1 2 F x x 0.371 15 4 1 2 M 2 2 1.912 15 5 1 2 M 2 2 1.039 15 6 1 2 F 2 2 0.611 15 7 1 2 F 2 2 0.371 15 8 1 2 M 1 2 0.890 16 1 x x M 1 2 -0.692 16 2 x x F 2 2 1.622 16 3 1 2 M 2 2 -0.049 16 4 1 2 F 1 2 -0.983 16 5 1 2 F 1 2 -0.829 17 1 x x M x x x 17 2 x x F 1 2 -0.212 17 3 1 2 M 1 1 -1.664 17 4 x x M 1 2 -0.378 17 5 1 2 F 1 1 -1.240 17 6 1 2 F 1 1 -0.931 17 7 4 5 F 1 1 -0.760 17 8 4 5 M 1 1 -0.411 17 9 4 5 F 1 2 -1.017 18 1 x x M x x x 18 2 x x F x x x 18 3 1 2 F 1 2 0.833 18 4 1 2 F 1 1 0.199 18 5 1 2 F 2 2 -0.229 18 6 1 2 F 2 2 -0.846 18 7 1 2 M 1 2 -0.560 18 8 x x F 1 1 -2.028 18 9 1 2 F 1 2 -0.160 18 10 1 2 F 2 2 2.256 18 11 x x M x x x 18 12 7 8 M 1 2 -0.082 18 13 7 8 F 1 1 -1.994 18 14 11 10 F 1 2 -0.297 18 15 11 10 M 1 2 0.544 18 16 11 10 F 1 2 3.027 18 17 11 10 F 1 2 2.050 19 1 x x M x x x 19 2 x x F 2 2 0.131 19 3 1 2 M 2 2 x 19 4 x x F 1 1 -0.040 19 5 1 2 M 2 2 1.286 19 6 3 4 F 1 2 -0.726 19 7 3 4 M 1 2 -0.543 19 8 3 4 M 1 2 0.495 20 1 x x M 1 1 -1.054 20 2 x x F x x x 20 3 1 2 F 1 1 x 20 4 1 2 M 1 1 -0.395 20 5 1 2 M 1 1 -0.675 20 6 1 2 F 1 1 0.097 20 7 1 2 M 1 1 -2.207 21 1 x x M x x x 21 2 x x F 2 2 -0.280 21 3 1 2 M 2 2 0.165 21 4 1 2 M 1 2 -0.032 21 5 1 2 M 2 2 -0.197 21 6 1 2 F 2 2 1.176 22 1 x x M x x x 22 2 x x F x x x 22 3 1 2 M 1 2 x 22 4 1 2 F 1 1 -1.583 22 5 1 2 F 1 1 -1.805 22 6 1 2 M 1 1 -1.779 23 1 x x M x x x 23 2 x x F 1 2 0.319 23 3 1 2 M 1 2 -0.115 23 4 1 2 M 1 2 -0.148 23 5 1 2 F 1 2 x 23 6 x x M 1 1 0.989 23 7 1 2 F 1 1 -0.092 23 8 1 2 F 1 2 0.628 23 9 6 5 M 1 1 0.709 23 10 6 5 M 1 1 -0.411 23 11 6 5 M 1 1 -0.032 24 1 x x M x x x 24 2 x x F x x x 24 3 1 2 M 1 2 x 24 4 1 2 F 1 1 -0.075 24 5 1 2 M 1 1 -0.741 24 6 1 2 F 1 2 x 25 1 x x M x x x 25 2 x x F x x x 25 3 1 2 F 2 2 x 25 4 1 2 M 2 2 0.940 25 5 1 2 M 2 2 0.495 25 6 1 2 M 1 1 x 26 1 x x M 1 2 -0.906 26 2 x x F 1 2 0.696 26 3 1 2 F 1 1 -1.583 26 4 1 2 M 1 2 0.033 26 5 1 2 M 1 2 -0.197 27 1 x x M 1 2 1.862 27 2 x x F 1 2 0.388 27 3 1 2 M 1 1 -1.169 27 4 1 2 F 1 2 x 27 5 x x M x x x 27 6 1 2 M 1 2 -1.202 27 7 5 4 F 2 2 1.896 27 8 5 4 F 1 2 0.371 27 9 5 4 M 2 2 1.829 28 1 x x M x x x 28 2 x x F x x x 28 3 1 2 F 1 2 -0.743 28 4 1 2 F 2 2 x 28 5 1 2 M 2 2 1.286 28 6 1 2 F 1 2 0.422 28 7 x x M 2 2 1.764 28 8 1 2 F 1 2 1.827 28 9 7 6 M 1 2 0.215 28 10 7 6 F 1 2 1.862 29 1 x x M x x x 29 2 x x F x x x 29 3 1 2 M 1 1 -0.741 29 4 1 2 M 1 2 1.269 29 5 1 2 F 1 1 -0.349 29 6 7 2 M 1 1 -1.005 29 7 x x M x x x 30 1 x x M x x x 30 2 x x F x x x 30 3 1 2 F 1 2 -0.469 30 4 1 2 F 1 2 1.210 30 5 1 2 F 1 2 0.971 30 6 1 2 F 2 2 2.376 30 7 1 2 M 1 2 0.594 30 8 x x M 1 2 0.577 30 9 8 5 M 1 2 1.302 30 10 8 5 M 1 1 -1.120 30 11 8 5 F 1 2 0.439 31 1 x x M x x x 31 2 x x F x x x 31 3 1 2 M 1 2 -0.247 31 4 1 2 M 1 2 -0.148 31 5 1 2 M 1 2 0.248 31 6 1 2 F 1 2 1.125 31 7 1 2 F 1 2 1.108 31 8 1 2 F 1 2 -0.297 31 9 x x F 1 2 x 31 10 5 9 M 1 1 -0.889 31 11 5 9 M 2 2 x 31 12 5 9 F 1 1 -1.428 32 1 x x M x x x 32 2 x x F x x x 32 3 1 2 M 1 1 -1.054 32 4 1 2 F 1 2 0.645 32 5 1 2 F 1 2 0.199 32 6 1 2 M 1 1 -0.329 32 7 1 2 F 1 2 -0.178 33 1 x x M x x x 33 2 x x F x x x 33 3 1 2 M 1 2 0.874 33 4 1 2 M 1 2 0.330 33 5 1 2 F 1 2 -0.897 33 6 x x F 1 2 -0.040 33 7 4 6 F 1 2 -0.092 33 8 4 6 M 1 2 0.676 33 9 4 6 M 1 2 0.643 34 1 x x M 1 2 0.544 34 2 x x F x x x 34 3 1 2 M 2 2 1.220 34 4 1 2 F 1 2 -0.315 34 5 1 2 M 1 2 0.198 35 1 x x M 1 2 -0.247 35 2 x x F 1 1 -0.623 35 3 1 2 M 1 2 0.956 35 4 x x F 2 2 0.628 35 5 3 4 F 2 2 0.628 35 6 3 4 M 1 2 -0.065 35 7 1 2 M 1 1 -0.609 35 8 x x F 1 1 -1.274 35 9 7 8 M 1 1 -1.499 35 10 7 8 M 1 1 -1.021 35 11 1 2 M 1 1 -1.367 36 1 x x M 2 2 0.627 36 2 x x F x x x 36 3 1 2 F 1 2 0.474 36 4 1 2 F 1 2 0.885 37 1 x x M 2 2 1.747 37 2 x x F x x x 37 3 1 2 M 1 2 x 37 4 x x F 2 2 2.187 37 5 3 4 M 1 2 -0.889 37 6 1 2 M 1 2 x 37 7 x x F 2 2 -0.315 37 8 6 7 M 2 2 x 37 9 6 7 M 2 2 0.149 37 10 6 7 M 1 2 -0.708 37 11 1 2 M 1 2 0.001 37 12 1 2 F 1 2 -0.092 38 1 x x F 1 2 x 38 2 x x M x x x 38 3 2 1 M 1 2 0.610 38 4 2 1 M 1 2 0.890 38 5 2 1 F 1 2 1.073 39 1 x x M x x x 39 2 x x F 2 2 1.090 39 3 1 2 M 1 2 0.561 39 4 1 2 F 1 2 -0.777 39 5 1 2 F 1 2 0.731 40 1 x x M x x x 40 2 x x F x x x 40 3 1 2 M 1 2 x 40 4 1 2 M 1 2 x 40 5 x x F 1 1 -0.486 40 6 4 5 M 1 1 -1.038 40 7 4 5 M 1 1 -0.840 40 8 4 5 M 1 2 -0.477 41 1 x x M x x x 41 2 x x F x x x 41 3 1 2 F 1 2 -0.537 41 4 1 2 F 1 2 x 41 5 1 2 F 1 2 -0.400 41 6 1 2 F 1 2 x 42 1 x x M 1 2 1.912 42 2 x x F 1 1 -0.966 42 3 1 2 M 1 1 -0.790 42 4 1 2 F 1 2 x 42 5 1 2 M 1 1 -0.873 43 1 x x M x x x 43 2 x x F x x x 43 3 1 2 F 1 2 x 43 4 1 2 M 1 2 0.594 43 5 1 2 F 1 1 -0.332 43 6 1 2 F 1 1 -0.983 43 7 1 2 M 1 2 -0.444 44 1 x x M 2 2 -0.477 44 2 x x F 1 2 0.319 44 3 1 2 F 1 2 -1.223 44 4 1 2 F 1 2 -0.332 44 5 1 2 M 1 2 x 44 6 x x F 1 2 0.919 44 7 5 6 F 2 2 1.793 44 8 5 6 F 1 1 -1.497 44 9 1 2 F 1 2 0.028 44 10 x x M x x x 44 11 10 9 F 1 2 -1.668 44 12 10 9 M 1 1 -1.548 44 13 10 9 F 1 1 -1.857 44 14 1 2 F 2 2 0.559 45 1 x x M 1 2 x 45 2 x x F 2 2 0.885 45 3 x x M x x x 45 4 1 2 F 1 2 -0.897 45 5 3 4 M 1 1 -1.301 45 6 3 4 M 1 1 -1.120 45 7 3 4 F 1 2 -0.88 45 8 1 2 F 2 2 1.125 46 1 x x M x x x 46 2 x x F x x x 46 3 1 2 M 1 1 x 46 4 x x F 1 1 -0.417 46 5 3 4 M 1 1 -0.840 46 6 3 4 F 1 1 -1.154 46 7 1 2 M 1 2 x 46 8 x x F 1 1 -0.794 46 9 7 8 M x x x 46 10 1 2 F 1 2 1.690 46 11 1 2 F 1 1 -0.023 47 1 x x M x x x 47 2 x x F x x x 47 3 1 2 M 1 2 x 47 4 x x F 1 2 0.182 47 5 3 4 F 1 2 -0.503 47 6 3 4 F 1 2 -0.983 47 7 3 4 F 2 2 0.388 47 8 1 2 M 1 2 -0.181 48 1 x x M 2 2 -1.169 48 2 x x F 2 2 0.559 48 3 1 2 M 2 2 -0.708 48 4 1 2 M 2 2 1.368 48 5 1 2 M 2 2 -0.972 49 1 x x M x x x 49 2 x x F 1 1 -0.812 49 3 1 2 F 1 1 -1.377 49 4 x x M 2 2 1.319 49 5 4 3 M 1 2 1.434 49 6 4 3 F 1 2 1.125 49 7 1 2 M 1 1 -0.296 49 8 1 2 F 1 1 -1.360 50 1 x x M x x x 50 2 x x F x x x 50 3 1 2 M 1 2 0.050 50 4 1 2 F 1 2 0.456 50 5 1 2 M 1 2 1.269 50 6 1 2 F 1 2 x 51 1 x x M x x x 51 2 x x F x x x 51 3 1 2 M 1 2 x 51 4 1 2 M 1 2 -0.741 51 5 1 2 M 2 2 x 52 1 x x M x x x 52 2 x x F x x x 52 3 1 2 F 1 2 0.474 52 4 1 2 F 2 2 x 52 5 1 2 F 2 2 x 52 6 1 2 F 2 2 0.782 53 1 x x M x x x 53 2 x x F x x x 53 3 1 2 M 1 1 x 53 4 x x F 2 2 -0.315 53 5 3 4 F 1 2 -0.075 53 6 3 4 M 1 2 -1.038 53 7 3 4 M 1 2 0.379 53 8 1 2 M 2 2 0.264 53 9 1 2 M 1 1 -1.515 53 10 x x F 1 2 0.456 53 11 9 10 F 1 1 x 53 12 9 10 M 1 2 -1.285 54 1 x x M 1 2 -0.378 54 2 x x F 1 2 x 54 3 1 2 M 1 1 -1.713 54 4 1 2 F 1 1 -0.606 54 5 1 2 M 2 2 0.511 54 6 1 2 F 1 1 -1.171 54 7 1 2 F 2 2 0.028 55 1 x x M x x x 55 2 x x F 1 2 0.645 55 3 1 2 F 2 2 x 55 4 1 2 M 1 2 -2.026 55 5 1 2 F 2 2 -0.332 56 1 x x M 1 1 -0.873 56 2 x x F 2 2 1.108 56 3 1 2 M 1 2 -0.346 56 4 1 2 M 1 2 0.116 56 5 1 2 F 1 2 -0.417 57 1 x x M x x x 57 2 x x F 1 2 0.217 57 3 1 2 F 1 1 -1.428 57 4 1 2 M 1 2 -0.708 57 5 1 2 M 1 2 -0.972 58 1 x x M x x x 58 2 x x F 1 2 -0.983 58 3 1 2 F 1 2 1.724 58 4 x x M 2 2 1.599 58 5 4 3 F 2 2 0.782 58 6 4 3 M 2 2 2.241 58 7 1 2 M 1 2 1.500 58 8 1 2 F 1 2 1.622 59 1 x x M x x x 59 2 x x F 1 1 -1.086 59 3 1 2 F 1 2 x 59 4 1 2 F 1 2 -0.709 59 5 1 2 M 1 2 -0.395 59 6 1 2 F 1 2 -0.315 60 1 x x M 1 2 x 60 2 x x F 1 2 1.433 60 3 1 2 F 1 2 1.365 60 4 1 2 M 2 2 2.670 60 5 1 2 F 1 2 0.302 61 1 x x M x x x 61 2 x x F x x x 61 3 x x M x x x 61 4 1 2 F 1 2 0.114 61 5 3 4 M 1 2 0.874 61 6 x x M 1 2 0.198 61 7 6 4 M 1 1 x 61 8 6 4 F 1 1 -0.657 61 9 1 2 M 1 2 0.116 62 1 x x M 1 2 x 62 2 x x F 1 1 x 62 3 1 2 F 1 2 1.947 62 4 1 2 F 1 1 0.456 62 5 1 2 M 1 2 0.033 63 1 x x M x x x 63 2 x x F x x x 63 3 1 2 F 1 2 x 63 4 1 2 M 1 2 -0.395 63 5 1 2 F 2 2 1.245 63 6 1 2 F 2 2 0.731 63 7 1 2 M 1 2 -0.840 63 8 1 2 M 1 2 0.116 64 1 x x M x x x 64 2 x x F x x x 64 3 x x M 2 2 -0.313 64 4 1 2 F 1 1 -0.572 64 5 3 2 M 1 2 0.066 64 6 3 2 M 2 2 -0.280 64 7 3 2 M 1 2 0.379 65 1 x x M x x x 65 2 x x F 1 2 x 65 3 1 2 M 1 2 x 65 4 1 2 F 1 2 -0.178 65 5 1 2 F 1 2 -0.589 65 6 1 2 F 1 2 -0.469 66 1 x x M 1 2 -0.840 66 2 x x F 1 2 -0.692 66 3 1 2 M 2 2 1.352 66 4 1 2 M 1 2 0.824 66 5 1 2 F 1 1 -0.572 67 1 x x M 2 2 1.187 67 2 x x F 2 2 0.011 67 3 1 2 M 2 2 0.511 67 4 1 2 F 2 2 1.090 67 5 1 2 F 2 2 0.474 68 1 x x M x x x 68 2 x x F 1 1 -0.863 68 3 1 2 M 1 2 -0.428 68 4 x x F x x x 68 5 3 4 M 1 2 -0.576 68 6 3 4 F 1 2 -1.308 68 7 1 2 F 1 2 0.302 68 8 1 2 F 1 2 1.193 69 1 x x M x x x 69 2 x x F 1 2 1.176 69 3 1 2 F 1 2 -0.246 69 4 1 2 F 1 1 -0.692 69 5 1 2 F 1 1 -0.417 ;;;; run