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PMID |
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TITLE |
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Genetic models for the analysis of data from the families of identical twins. |
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ABSTRACT |
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Genetic models are described which exploit the unique relationships that exist within the families of identical twins to obtain weighted least squares estimates of additive, dominance and epistatic components of genetic variance as well as estimates of the contributions of X-linked genes, maternal effects and three sources of environmental variation. Since all of the relationships required to achieve a resolution of these variance components are contained within each family unit, the model would appear to be superior to previous approaches to the analysis of quantitative traits in man. |
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DATE PUBLISHED |
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HISTORY |
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PUBSTATUS |
PUBSTATUSDATE |
pubmed |
1976/08/01 |
medline |
1976/08/01 00:01 |
entrez |
1976/08/01 00:00 |
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AUTHORS |
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NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
Nance WE |
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Nance |
W E |
WE |
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Corey LA |
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Corey |
L A |
LA |
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INVESTIGATORS |
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JOURNAL |
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VOLUME: 83 |
ISSUE: 4 |
TITLE: Genetics |
ISOABBREVIATION: Genetics |
YEAR: 1976 |
MONTH: Aug |
DAY: |
MEDLINEDATE: |
SEASON: |
CITEDMEDIUM: Print |
ISSN: 0016-6731 |
ISSNTYPE: Print |
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MEDLINE JOURNAL |
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MEDLINETA: Genetics |
COUNTRY: United States |
ISSNLINKING: 0016-6731 |
NLMUNIQUEID: 0374636 |
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PUBLICATION TYPE |
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PUBLICATIONTYPE TEXT |
Journal Article |
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COMMENTS AND CORRECTIONS |
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GRANTS |
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GENERAL NOTE |
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KEYWORDS |
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MESH HEADINGS |
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DESCRIPTORNAME |
QUALIFIERNAME |
Biometry |
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Environment |
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Female |
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Genes, Dominant |
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Genetic Linkage |
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Genetic Variation |
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Humans |
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Models, Biological |
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Pregnancy |
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Sex Chromosomes |
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Twins |
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Twins, Monozygotic |
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SUPPLEMENTARY MESH |
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GENE SYMBOLS |
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CHEMICALS |
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OTHER ID's |
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