Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
9573643
TITLE
A comparison of adult female twins from opposite-sex and same-sex pairs on variables related to reproduction.
ABSTRACT
In several litter-bearing species, prenatal exposure of a female fetus to hormones from adjacent male fetuses can lead to later effects on various anatomical and behavioral characteristics of the female, including a number related to reproduction. To see if such traits are also affected in humans, adult female twins from a large Australian sample who had male cotwins were compared to females with female cotwins on 90 questionnaire items related to reproductive functions. No substantial effects could be clearly demonstrated, although some weak effects remained a possibility. Some variables, such as age at first menstruation, age at first pregnancy, and height, were consistent in direction with results from the animal literature, although the effect sizes were small and not statistically significant.
DATE PUBLISHED
1998 Jan
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 1998/05/09
medline 1998/05/09 00:01
entrez 1998/05/09 00:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Loehlin JC Loehlin J C JC Department of Psychology, University of Texas, Austin 78712, USA. loehlin@psy.utexas.edu
Martin NG Martin N G NG
INVESTIGATORS
JOURNAL
VOLUME: 28
ISSUE: 1
TITLE: Behavior genetics
ISOABBREVIATION: Behav. Genet.
YEAR: 1998
MONTH: Jan
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0001-8244
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Behav Genet
COUNTRY: United States
ISSNLINKING: 0001-8244
NLMUNIQUEID: 0251711
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Comparative Study
Journal Article
Research Support, U.S. Gov't, P.H.S.
Twin Study
COMMENTS AND CORRECTIONS
GRANTS
GRANTID AGENCY COUNTRY
880748 PHS HHS United States
AA07535 NIAAA NIH HHS United States
NS00153 NINDS NIH HHS United States
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adult
Analysis of Variance
Androgens physiology
Female physiology
Humans physiology
Logistic Models physiology
Male physiology
Pregnancy physiology
Prenatal Exposure Delayed Effects physiology
Reproduction physiology
Sex Factors physiology
Twins, Dizygotic physiology
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
REGISTRYNUMBER NAMEOFSUBSTANCE
0 Androgens
OTHER ID's