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PMID |
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TITLE |
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Nicotine withdrawal in women. |
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ABSTRACT |
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Associations between self-report symptom profiles for nicotine withdrawal, personality (TPQ, EPQ-R), life-time history of psychopathology and smoking history were examined in data obtained from 553 female adult Australian twins (246 regular smokers), aged 32-48 years, who had participated in a telephone interview survey that included life-time assessments of smoking history, nicotine dependence and symptoms of withdrawal. Two hundred and two respondents were from high-risk pairs where either the respondent or the respondent's co-twin had reported a life-time history of alcohol dependence; 351 were from control pairs. Latent class analysis was used to identify subtypes ('classes') of smokers reporting similar withdrawal symptom profiles. Three major classes were identified which appeared to represent a continuum from mild to severe nicotine withdrawal. Smokers from the severe withdrawal class were best characterized by hands shaking and by the prominence of depressive features. There were marked increases in life-time alcohol dependence rates as a function of severity class. In contrast, significantly elevated rates of major depression, conduct disorder and anxiety disorder were observed only among smokers from the most severe withdrawal class. Neuroticism was the only personality factor strongly associated with the development of withdrawal symptoms. |
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DATE PUBLISHED |
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HISTORY |
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PUBSTATUS |
PUBSTATUSDATE |
pubmed |
1997/07/01 00:00 |
medline |
1997/09/18 00:01 |
entrez |
1997/07/01 00:00 |
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AUTHORS |
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NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
Madden PA |
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Madden |
P A |
PA |
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Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA. |
Bucholz KK |
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Bucholz |
K K |
KK |
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Dinwiddie SH |
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Dinwiddie |
S H |
SH |
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Slutske WS |
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Slutske |
W S |
WS |
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Bierut LJ |
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Bierut |
L J |
LJ |
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Statham DJ |
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Statham |
D J |
DJ |
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Dunne MP |
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Dunne |
M P |
MP |
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Martin NG |
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Martin |
N G |
NG |
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Heath AC |
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Heath |
A C |
AC |
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INVESTIGATORS |
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JOURNAL |
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VOLUME: 92 |
ISSUE: 7 |
TITLE: Addiction (Abingdon, England) |
ISOABBREVIATION: Addiction |
YEAR: 1997 |
MONTH: Jul |
DAY: |
MEDLINEDATE: |
SEASON: |
CITEDMEDIUM: Print |
ISSN: 0965-2140 |
ISSNTYPE: Print |
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MEDLINE JOURNAL |
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MEDLINETA: Addiction |
COUNTRY: England |
ISSNLINKING: 0965-2140 |
NLMUNIQUEID: 9304118 |
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PUBLICATION TYPE |
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PUBLICATIONTYPE TEXT |
Journal Article |
Research Support, Non-U.S. Gov't |
Research Support, U.S. Gov't, P.H.S. |
Twin Study |
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COMMENTS AND CORRECTIONS |
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GRANTS |
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GRANTID |
AGENCY |
COUNTRY |
AA07535 |
NIAAA NIH HHS |
United States |
AA07728 |
NIAAA NIH HHS |
United States |
DA00272 |
NIDA NIH HHS |
United States |
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GENERAL NOTE |
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KEYWORDS |
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MESH HEADINGS |
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DESCRIPTORNAME |
QUALIFIERNAME |
Adult |
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Diseases in Twins |
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Female |
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Humans |
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Mental Disorders |
chemically induced |
Middle Aged |
chemically induced |
Nicotine |
adverse effects |
Personality |
adverse effects |
Smoking |
adverse effects |
Substance Withdrawal Syndrome |
psychology |
Tobacco Use Disorder |
complications |
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SUPPLEMENTARY MESH |
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GENE SYMBOLS |
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CHEMICALS |
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REGISTRYNUMBER |
NAMEOFSUBSTANCE |
54-11-5 |
Nicotine |
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OTHER ID's |
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