|
|
| PMID |
|
|
| TITLE |
|
| Alcohol sensitivity and smoking history in men and women. |
|
| ABSTRACT |
|
|
|
| Many studies have found genetic effects to contribute to alcoholism risk in both men and women. Based on preliminary evidence for shared genetic risk between smoking and drinking problems, a reanalysis of alcohol challenge data on 412 Australian twins was performed to explore the possibility that smoking may diminish or moderate the intoxicating effects of alcohol. We found history of smoking to be strongly associated with self-reported intoxication after alcohol challenge in women (women: r = -0.44 +/- 0.08; men: r = -0.21 +/- 0.08), comparable with self-reported average weekly consumption of alcohol, which was more strongly associated in men (women: r = -0.37 +/- 0.07; men: r = -0.54 +/- 0.06). Structural equation model-fitting indicated a strong association between heavy drinking and smoking, but the association between smoking and postalcohol intoxication remained even when the effects of heavy drinking were controlled for. These results prompt the question of whether smoking cigarettes directly influences the transition from moderate to excessive use of alcohol by diminishing feelings of alcohol intoxication. |
|
| DATE PUBLISHED |
|
|
| HISTORY |
|
| PUBSTATUS |
PUBSTATUSDATE |
| pubmed |
1995/10/01 |
| medline |
1995/10/01 00:01 |
| entrez |
1995/10/01 00:00 |
|
| AUTHORS |
|
| NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
| Madden PA |
|
Madden |
P A |
PA |
|
Department of Psychiatry, Washington University School of Medicine, Medical School, St. Louis, Missouri 63110, USA. |
| Heath AC |
|
Heath |
A C |
AC |
|
|
| Starmer GA |
|
Starmer |
G A |
GA |
|
|
| Whitfield JB |
|
Whitfield |
J B |
JB |
|
|
| Martin NG |
|
Martin |
N G |
NG |
|
|
|
| INVESTIGATORS |
|
|
| JOURNAL |
|
| VOLUME: 19 |
| ISSUE: 5 |
| TITLE: Alcoholism, clinical and experimental research |
| ISOABBREVIATION: Alcohol. Clin. Exp. Res. |
| YEAR: 1995 |
| MONTH: Oct |
| DAY: |
| MEDLINEDATE: |
| SEASON: |
| CITEDMEDIUM: Print |
| ISSN: 0145-6008 |
| ISSNTYPE: Print |
|
| MEDLINE JOURNAL |
|
| MEDLINETA: Alcohol Clin Exp Res |
| COUNTRY: England |
| ISSNLINKING: 0145-6008 |
| NLMUNIQUEID: 7707242 |
|
| PUBLICATION TYPE |
|
| PUBLICATIONTYPE TEXT |
| Journal Article |
| Research Support, Non-U.S. Gov't |
| Research Support, U.S. Gov't, P.H.S. |
| Twin Study |
|
| COMMENTS AND CORRECTIONS |
|
|
| GRANTS |
|
| GRANTID |
AGENCY |
COUNTRY |
| AA07535 |
NIAAA NIH HHS |
United States |
| AA07728 |
NIAAA NIH HHS |
United States |
| DA07261 |
NIDA NIH HHS |
United States |
|
| GENERAL NOTE |
|
|
| KEYWORDS |
|
|
| MESH HEADINGS |
|
| DESCRIPTORNAME |
QUALIFIERNAME |
| Adolescent |
|
| Adult |
|
| Alcoholic Intoxication |
psychology |
| Alcoholism |
psychology |
| Australia |
psychology |
| Female |
psychology |
| Genotype |
psychology |
| Humans |
psychology |
| Male |
psychology |
| Motivation |
psychology |
| Risk Factors |
psychology |
| Smoking |
psychology |
|
| SUPPLEMENTARY MESH |
|
|
| GENE SYMBOLS |
|
|
| CHEMICALS |
|
|
| OTHER ID's |
|
|
|
