|
|
| PMID |
|
|
| TITLE |
|
| Seasonal changes in mood and behavior. The role of genetic factors. |
|
| ABSTRACT |
|
| BACKGROUND |
NlmCategory: BACKGROUND |
| Seasonal rhythms in mood and behavior (seasonality) have been reported to occur in the general population. Seasonal affective disorder, a clinically diagnosed syndrome, is believed to represent the morbid extreme of a spectrum of seasonality. Two types of seasonality have been clinically described: one characterized by a winter pattern and a second by a summer pattern of depressive mood disturbance. |
| METHODS |
NlmCategory: METHODS |
| By using methods of univariate and multivariate genetic analysis, we examined the relative contribution of genetic and environmental factors to the risk of seasonality symptoms that were assessed by a mailed questionnaire of 4639 adult twins from a volunteer-based registry in Australia. |
| RESULTS |
NlmCategory: RESULTS |
| Seasonality was associated with a winter rather than a summer pattern of mood and behavioral change. In each behavioral domain (ie, mood, energy, social activity, sleep, appetite, and weight), a significant genetic influence on the reporting of seasonal changes was found. Consistent with the hypothesis of a seasonal syndrome, genetic effects were found to exert a global influence across all behavioral changes, accounting for at least 29% of the variance in seasonality in men and women. |
| CONCLUSIONS |
NlmCategory: CONCLUSIONS |
| There is a tendency for seasonal changes in mood and behavior to run in families, especially seasonality of the winter type, and this is largely due to a biological predisposition. These findings support continuing efforts to understand the role of seasonality in the development of mood disorders. |
|
| DATE PUBLISHED |
|
|
| HISTORY |
|
| PUBSTATUS |
PUBSTATUSDATE |
| pubmed |
1996/01/01 |
| medline |
1996/01/01 00:01 |
| entrez |
1996/01/01 00:00 |
|
| AUTHORS |
|
| NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
| Madden PA |
|
Madden |
P A |
PA |
|
Department of Psychiatry, Washington University School of Medicine, St Louis, Mo, USA. |
| Heath AC |
|
Heath |
A C |
AC |
|
|
| Rosenthal NE |
|
Rosenthal |
N E |
NE |
|
|
| Martin NG |
|
Martin |
N G |
NG |
|
|
|
| INVESTIGATORS |
|
|
| JOURNAL |
|
| VOLUME: 53 |
| ISSUE: 1 |
| TITLE: Archives of general psychiatry |
| ISOABBREVIATION: Arch. Gen. Psychiatry |
| YEAR: 1996 |
| MONTH: Jan |
| DAY: |
| MEDLINEDATE: |
| SEASON: |
| CITEDMEDIUM: Print |
| ISSN: 0003-990X |
| ISSNTYPE: Print |
|
| MEDLINE JOURNAL |
|
| MEDLINETA: Arch Gen Psychiatry |
| COUNTRY: United States |
| ISSNLINKING: 0003-990X |
| NLMUNIQUEID: 0372435 |
|
| PUBLICATION TYPE |
|
| PUBLICATIONTYPE TEXT |
| Journal Article |
| Research Support, Non-U.S. Gov't |
| Research Support, U.S. Gov't, P.H.S. |
|
| COMMENTS AND CORRECTIONS |
|
|
| GRANTS |
|
| GRANTID |
AGENCY |
COUNTRY |
| AA07535 |
NIAAA NIH HHS |
United States |
| DA07261 |
NIDA NIH HHS |
United States |
|
| GENERAL NOTE |
|
|
| KEYWORDS |
|
|
| MESH HEADINGS |
|
| DESCRIPTORNAME |
QUALIFIERNAME |
| Adult |
|
| Affect |
|
| Aged |
|
| Appetite |
|
| Australia |
epidemiology |
| Body Weight |
epidemiology |
| Diseases in Twins |
genetics |
| Family |
genetics |
| Female |
genetics |
| Humans |
genetics |
| Male |
genetics |
| Middle Aged |
genetics |
| Registries |
genetics |
| Seasonal Affective Disorder |
genetics |
| Seasons |
genetics |
| Sleep |
genetics |
| Social Environment |
genetics |
|
| SUPPLEMENTARY MESH |
|
|
| GENE SYMBOLS |
|
|
| CHEMICALS |
|
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| OTHER ID's |
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|
