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PMID |
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TITLE |
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Genetic models for the natural history of smoking: evidence for a genetic influence on smoking persistence. |
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ABSTRACT |
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We reanalyze data from the 1981 mailed questionnaire survey of the Australian twin register, to test for a genetic effect on smoking persistence (whether or not a smoker quits smoking). In the young cohort, aged 18-30 years, there are too few ex-smokers to permit resolution of genetic and non-genetic models. In the older cohort, we find a significant and substantial genetic effect on smoking persistence, accounting for 53% of the variance. This genetic effect on smoking persistence is independent of genetic effects on smoking initiation. |
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DATE PUBLISHED |
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HISTORY |
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PUBSTATUS |
PUBSTATUSDATE |
pubmed |
1993/01/01 |
medline |
1993/01/01 00:01 |
entrez |
1993/01/01 00:00 |
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AUTHORS |
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NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
Heath AC |
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Heath |
A C |
AC |
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Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110. |
Martin NG |
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Martin |
N G |
NG |
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INVESTIGATORS |
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JOURNAL |
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VOLUME: 18 |
ISSUE: 1 |
TITLE: Addictive behaviors |
ISOABBREVIATION: Addict Behav |
YEAR: |
MONTH: |
DAY: |
MEDLINEDATE: 1993 Jan-Feb |
SEASON: |
CITEDMEDIUM: Print |
ISSN: 0306-4603 |
ISSNTYPE: Print |
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MEDLINE JOURNAL |
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MEDLINETA: Addict Behav |
COUNTRY: ENGLAND |
ISSNLINKING: 0306-4603 |
NLMUNIQUEID: 7603486 |
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PUBLICATION TYPE |
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PUBLICATIONTYPE TEXT |
Journal Article |
Research Support, Non-U.S. Gov't |
Research Support, U.S. Gov't, P.H.S. |
Review |
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COMMENTS AND CORRECTIONS |
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GRANTS |
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GRANTID |
AGENCY |
COUNTRY |
AA07535 |
NIAAA NIH HHS |
United States |
AA07728 |
NIAAA NIH HHS |
United States |
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GENERAL NOTE |
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KEYWORDS |
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MESH HEADINGS |
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DESCRIPTORNAME |
QUALIFIERNAME |
Adolescent |
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Adult |
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Age Factors |
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Behavior, Addictive |
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Cohort Studies |
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Female |
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Humans |
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Male |
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Models, Genetic |
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Smoking |
genetics |
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SUPPLEMENTARY MESH |
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GENE SYMBOLS |
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CHEMICALS |
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OTHER ID's |
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