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PMID |
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TITLE |
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Risk factors for atherosclerosis in twins. |
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ABSTRACT |
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We performed multivariate genetic analyses of cardiovascular risk factors from two sets of data on US and Australian female twins. Similar models for body mass index (BMI), serum low density (LDL) and high density (HDL) lipoproteins, including age as a covariate, were fitted successfully to both groups. These suggested that BMI, or genes responsible for a significant proportion of the variance of BMI, explained correlations between lipid subfractions, as well as those between blood pressure and lipid subfractions, especially HDL. |
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DATE PUBLISHED |
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HISTORY |
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PUBSTATUS |
PUBSTATUSDATE |
pubmed |
1993/01/01 |
medline |
1993/01/01 00:01 |
entrez |
1993/01/01 00:00 |
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AUTHORS |
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NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
Duffy DL |
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Duffy |
D L |
DL |
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Queensland Institute of Medical Research, Brisbane, Australia. |
O'Connell DL |
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O'Connell |
D L |
DL |
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Heller RF |
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Heller |
R F |
RF |
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Martin NG |
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Martin |
N G |
NG |
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INVESTIGATORS |
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JOURNAL |
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VOLUME: 10 |
ISSUE: 6 |
TITLE: Genetic epidemiology |
ISOABBREVIATION: Genet. Epidemiol. |
YEAR: 1993 |
MONTH: |
DAY: |
MEDLINEDATE: |
SEASON: |
CITEDMEDIUM: Print |
ISSN: 0741-0395 |
ISSNTYPE: Print |
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MEDLINE JOURNAL |
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MEDLINETA: Genet Epidemiol |
COUNTRY: United States |
ISSNLINKING: 0741-0395 |
NLMUNIQUEID: 8411723 |
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PUBLICATION TYPE |
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PUBLICATIONTYPE TEXT |
Journal Article |
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COMMENTS AND CORRECTIONS |
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GRANTS |
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GENERAL NOTE |
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KEYWORDS |
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MESH HEADINGS |
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DESCRIPTORNAME |
QUALIFIERNAME |
Adolescent |
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Adult |
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Aged |
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Arteriosclerosis |
genetics |
Australia |
epidemiology |
Blood Pressure |
epidemiology |
Body Mass Index |
epidemiology |
Diseases in Twins |
genetics |
Female |
genetics |
Humans |
genetics |
Lipoproteins, HDL |
genetics |
Lipoproteins, LDL |
genetics |
Middle Aged |
genetics |
Multivariate Analysis |
genetics |
Risk Factors |
genetics |
Twins, Dizygotic |
statistics & numerical data |
Twins, Monozygotic |
statistics & numerical data |
United States |
epidemiology |
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SUPPLEMENTARY MESH |
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GENE SYMBOLS |
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CHEMICALS |
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REGISTRYNUMBER |
NAMEOFSUBSTANCE |
0 |
Lipoproteins, HDL |
0 |
Lipoproteins, LDL |
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OTHER ID's |
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