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| PMID |
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| TITLE |
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| Event-related potentials associated with covert orientation of visual attention in Parkinson's disease. |
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| ABSTRACT |
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| Event-related potentials (ERPs) were measured in a group of patients with idiopathic Parkinson's disease and compared with a matched control group during a task involving covert orientation of visual attention. Central warning cues directed attention to the probable location of a lateralized signal that required a button-press response. Parkinson patients had enhanced post-cue P1 (at Oz) and P2 (at Cz) amplitudes, delayed N1 (at Oz) latencies, and diminished CNV amplitudes. Post-target amplitudes were similar to controls, except for an enhanced P1 to invalidly cued targets, and delayed N1 and P3 target latencies. These results indicate that Parkinson patients, in addition to their motor deficits, process spatial cues more effortfully and slowly, have impaired response preparation, and process imperative stimuli more slowly. |
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| DATE PUBLISHED |
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| HISTORY |
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| PUBSTATUS |
PUBSTATUSDATE |
| pubmed |
1993/12/01 |
| medline |
1993/12/01 00:01 |
| entrez |
1993/12/01 00:00 |
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| AUTHORS |
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| NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
| Wright MJ |
|
Wright |
M J |
MJ |
|
Department of Psychology, University of Queensland, Brisbane, Australia. |
| Geffen GM |
|
Geffen |
G M |
GM |
|
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| Geffen LB |
|
Geffen |
L B |
LB |
|
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| INVESTIGATORS |
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| JOURNAL |
|
| VOLUME: 31 |
| ISSUE: 12 |
| TITLE: Neuropsychologia |
| ISOABBREVIATION: Neuropsychologia |
| YEAR: 1993 |
| MONTH: Dec |
| DAY: |
| MEDLINEDATE: |
| SEASON: |
| CITEDMEDIUM: Print |
| ISSN: 0028-3932 |
| ISSNTYPE: Print |
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| MEDLINE JOURNAL |
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| MEDLINETA: Neuropsychologia |
| COUNTRY: England |
| ISSNLINKING: 0028-3932 |
| NLMUNIQUEID: 0020713 |
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| PUBLICATION TYPE |
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| PUBLICATIONTYPE TEXT |
| Journal Article |
| Research Support, Non-U.S. Gov't |
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| COMMENTS AND CORRECTIONS |
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| GRANTS |
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| GENERAL NOTE |
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| KEYWORDS |
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| MESH HEADINGS |
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| DESCRIPTORNAME |
QUALIFIERNAME |
| Aged |
|
| Animals |
|
| Attention |
physiology |
| Cerebral Cortex |
physiopathology |
| Contingent Negative Variation |
physiology |
| Cues |
physiology |
| Dominance, Cerebral |
physiology |
| Evoked Potentials, Visual |
physiology |
| Female |
physiology |
| Guinea Pigs |
physiology |
| Humans |
physiology |
| Male |
physiology |
| Middle Aged |
physiology |
| Orientation |
physiology |
| Parkinson Disease |
physiopathology |
| Psychomotor Performance |
physiology |
| Reaction Time |
physiology |
| Visual Fields |
physiology |
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| SUPPLEMENTARY MESH |
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| GENE SYMBOLS |
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| CHEMICALS |
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| OTHER ID's |
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