Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
8123478
TITLE
Comparability of naevus counts between and within examiners, and comparison with computer image analysis.
ABSTRACT
In the course of an investigation of melanocytic naevus development in Queensland, Australia, whole-body naevus counts of 66 adolescents were performed separately by two nurse examiners on two occasions on average 4 weeks apart. There was good agreement between the two examiners for counts of total naevi on the whole body (intra-class correlation coefficient = 0.96) and at selected subsites (face, neck, back, upper arms, lower arms). Agreement was lower when raised naevi only were counted (0.83). Intra-examiner repeatability was high for both nurses, particularly for the more experienced examiner (intra-class correlation coefficients = 0.98 and 0.91 for total naevi on the whole body), and was consistently better when all naevi were counted rather than naevi of a particular size. Independent counts of naevi on the back using a computer imaging technique were reproducible (intra-class correlation coefficient = 0.92), but showed only moderate agreement with counts by the nurse examiners. Overall, these results demonstrate high comparability of naevus counts between and within similarly trained examiners. They do not support the common practice in epidemiological studies of restricting counts to naevi larger than 2 mm, or of counting raised naevi only.
DATE PUBLISHED
1994 Mar
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 1994/03/01
medline 1994/03/01 00:01
entrez 1994/03/01 00:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Aitken JF Aitken J F JF Queensland Institute of Medical Research, Brisbane, Australia.
Green A Green A A
Eldridge A Eldridge A A
Green L Green L L
Pfitzner J Pfitzner J J
Battistutta D Battistutta D D
Martin NG Martin N G NG
INVESTIGATORS
JOURNAL
VOLUME: 69
ISSUE: 3
TITLE: British journal of cancer
ISOABBREVIATION: Br. J. Cancer
YEAR: 1994
MONTH: Mar
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0007-0920
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Br J Cancer
COUNTRY: England
ISSNLINKING: 0007-0920
NLMUNIQUEID: 0370635
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
COMMENTS AND CORRECTIONS
REFTYPE REFSOURCE REFPMID NOTE
Cites J Natl Cancer Inst. 1984 Feb;72(2):257-66 6582314
Cites Int J Cancer. 1985 Mar 15;35(3):297-300 3972472
Cites N Engl J Med. 1987 Oct 22;317(17):1098 3657876
Cites Am J Epidemiol. 1988 Apr;127(4):703-12 3354537
Cites J Am Acad Dermatol. 1989 Jun;20(6):1054-60 2754055
Cites Am J Epidemiol. 1992 Aug 1;136(3):344-55 1415153
Cites J Clin Epidemiol. 1991;44(7):633-40 2066743
Cites Br J Cancer. 1991 Aug;64(2):373-6 1892767
Cites Melanoma Res. 1991 Nov-Dec;1(4):231-6 1823631
Cites J Natl Cancer Inst. 1992 Sep 16;84(18):1427-32 1512795
Cites Epidemiol Rev. 1989;11:204-21 2680556
GRANTS
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adolescent
Child
Diseases in Twins
Female
Humans
Image Processing, Computer-Assisted
Longitudinal Studies
Male
Nevus, Pigmented pathology
Observer Variation pathology
Oncology Nursing pathology
Skin Neoplasms pathology
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's
OTHERID SOURCE
PMC1968854 NLM