|
|
| PMID |
|
|
| TITLE |
|
| Osteoporosis in rheumatoid arthritis. A monozygotic co-twin control study. |
|
| ABSTRACT |
|
| OBJECTIVE |
NlmCategory: OBJECTIVE |
| To quantify the magnitude and distribution of osteoporosis in rheumatoid arthritis (RA). |
| METHODS |
NlmCategory: METHODS |
| Bone mineral density (BMD) was measured by dual x-ray absorptiometry, in a monozygotic co-twin control study. |
| RESULTS |
NlmCategory: RESULTS |
| BMD was reduced at most skeletal sites in the twin with RA compared with the co-twin (lumbar spine 4.6%, femoral neck 9.7%, total body 5.7%). Differences in lean soft tissue (5.6% for total body) correlated with differences in BMD between twins at multiple sites. |
| CONCLUSION |
NlmCategory: CONCLUSIONS |
| Osteoporosis in RA is generalized and may be related to loss of mobility or muscle mass associated with the disease. |
|
| DATE PUBLISHED |
|
|
| HISTORY |
|
| PUBSTATUS |
PUBSTATUSDATE |
| pubmed |
1995/06/01 |
| medline |
1995/06/01 00:01 |
| entrez |
1995/06/01 00:00 |
|
| AUTHORS |
|
| NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
| Sambrook PN |
|
Sambrook |
P N |
PN |
|
Garvan Institute of Medical Research, St. Vincent's Hospital, Sydney, Australia. |
| Spector TD |
|
Spector |
T D |
TD |
|
|
| Seeman E |
|
Seeman |
E |
E |
|
|
| Bellamy N |
|
Bellamy |
N |
N |
|
|
| Buchanan RR |
|
Buchanan |
R R |
RR |
|
|
| Duffy DL |
|
Duffy |
D L |
DL |
|
|
| Martin NG |
|
Martin |
N G |
NG |
|
|
| Prince R |
|
Prince |
R |
R |
|
|
| Owen E |
|
Owen |
E |
E |
|
|
| Silman AJ |
|
Silman |
A J |
AJ |
|
|
|
| INVESTIGATORS |
|
|
| JOURNAL |
|
| VOLUME: 38 |
| ISSUE: 6 |
| TITLE: Arthritis and rheumatism |
| ISOABBREVIATION: Arthritis Rheum. |
| YEAR: 1995 |
| MONTH: Jun |
| DAY: |
| MEDLINEDATE: |
| SEASON: |
| CITEDMEDIUM: Print |
| ISSN: 0004-3591 |
| ISSNTYPE: Print |
|
| MEDLINE JOURNAL |
|
| MEDLINETA: Arthritis Rheum |
| COUNTRY: UNITED STATES |
| ISSNLINKING: 0004-3591 |
| NLMUNIQUEID: 0370605 |
|
| PUBLICATION TYPE |
|
| PUBLICATIONTYPE TEXT |
| Journal Article |
| Research Support, Non-U.S. Gov't |
| Twin Study |
|
| COMMENTS AND CORRECTIONS |
|
|
| GRANTS |
|
|
| GENERAL NOTE |
|
|
| KEYWORDS |
|
|
| MESH HEADINGS |
|
| DESCRIPTORNAME |
QUALIFIERNAME |
| Arthritis, Rheumatoid |
genetics |
| Bone Density |
physiology |
| Diseases in Twins |
genetics |
| Female |
genetics |
| Femur Neck |
physiopathology |
| Great Britain |
epidemiology |
| Humans |
epidemiology |
| Lumbar Vertebrae |
physiopathology |
| Male |
physiopathology |
| Osteoporosis |
genetics |
| Questionnaires |
genetics |
| Registries |
genetics |
| Regression Analysis |
genetics |
| Twins, Monozygotic |
genetics |
|
| SUPPLEMENTARY MESH |
|
|
| GENE SYMBOLS |
|
|
| CHEMICALS |
|
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| OTHER ID's |
|
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|
