Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
7733853
TITLE
Personality and the inheritance of smoking behavior: a genetic perspective.
ABSTRACT
In contrast to the extensive research effort to understand the genetic contribution to alcoholism risk, there has been little research directed at understanding genetic influences on smoking behavior. Data from large twin studies in Scandinavia and Australia are consistent with a major genetic influence on the probability that an individual will become a smoker ("initiation") and will persist in the smoking habit once smoking has started ("persistence"). We use data from the 1988/1989 follow-up survey of the Australian NH&MRC twin panel to determine to what degree personality measures (Tridimensional Personality Questionnaire, Eysenck Personality Questionnaire--Revised) and attitudinal and sociodemographic variables (social and political conservatism, education, religious involvement) might account for genetic or environmental influences on smoking. While we find significant phenotypic associations between these variables and smoking, these are too modest to account for much of the genetic variance. Possible mechanisms by which this genetic variance may arise are discussed.
DATE PUBLISHED
1995 Mar
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 1995/03/01
medline 1995/03/01 00:01
entrez 1995/03/01 00:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Heath AC Heath A C AC Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Madden PA Madden P A PA
Slutske WS Slutske W S WS
Martin NG Martin N G NG
INVESTIGATORS
JOURNAL
VOLUME: 25
ISSUE: 2
TITLE: Behavior genetics
ISOABBREVIATION: Behav. Genet.
YEAR: 1995
MONTH: Mar
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0001-8244
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Behav Genet
COUNTRY: United States
ISSNLINKING: 0001-8244
NLMUNIQUEID: 0251711
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Twin Study
COMMENTS AND CORRECTIONS
GRANTS
GRANTID AGENCY COUNTRY
AA07535 NIAAA NIH HHS United States
AA07728 NIAAA NIH HHS United States
MH31302 NIMH NIH HHS United States
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adolescent
Age Factors
Age of Onset
Attitude to Health
Australia
Codependency (Psychology)
Educational Status
Female
Humans
Logistic Models
Male
Odds Ratio
Personality genetics
Personality Tests genetics
Questionnaires genetics
Religion and Medicine genetics
Risk Factors genetics
Sex Factors genetics
Smoking psychology
Socioeconomic Factors psychology
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's