Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
7196668
TITLE
Sex differences in the inheritance of some anthropometric characters in twins.
ABSTRACT
Biometrical genetical techniques have been applied to the analysis of certain anthropometric characters measured in 134 pairs of adult twins. After allowing for assortative mating it appears that there is a family environment (E2) component for variation in height larger than previously reported. "Fatness" traits - weight, ponderal index, and skinfold thickness - all show higher heritabilities in males and substantial E2 components in females, and reasons for this are discussed. The same is true for cephalic index and forearm length but the reason for these differences is not so obvious. Head length shows a much higher heritability than head breadth. A larger sample of DZ opposite-sex pairs would allow more powerful discrimination, but the variety of patterns of variation revealed by the model-fitting approach used here justify its use over more traditional techniques.
DATE PUBLISHED
1980
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 1980/01/01
medline 1980/01/01 00:01
entrez 1980/01/01 00:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Clarke P Clarke P P
Jardine R Jardine R R
Martin NG Martin N G NG
Stark AE Stark A E AE
Walsh RJ Walsh R J RJ
INVESTIGATORS
JOURNAL
VOLUME: 29
ISSUE: 3
TITLE: Acta geneticae medicae et gemellologiae
ISOABBREVIATION: Acta Genet Med Gemellol (Roma)
YEAR: 1980
MONTH:
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0001-5660
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Acta Genet Med Gemellol (Roma)
COUNTRY: Italy
ISSNLINKING: 0001-5660
NLMUNIQUEID: 0370314
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, Non-U.S. Gov't
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Anthropometry
Body Height
Body Weight
Female
Genetic Variation
Humans
Male
Mathematics
Models, Genetic
Pregnancy
Sex Factors
Skinfold Thickness
Twins
Twins, Dizygotic
Twins, Monozygotic
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's