Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
7181445
TITLE
A genetical analysis of covariation between finger ridge counts.
ABSTRACT
1. The genetical and environmental structure of covariation between finger ridge counts in twin and sibling data has been analysed using the method of Martin and Eaves (1977) adapted from Jöreskog. 2. The model for environmental covariance contains a single factor loading on all ten digits but most environmental variance is specific to each finger. 3. For additive genetic variance there is one common factor loading on all digits. There are also five other independent factors, one for each digit. The thumb factor loads only on the two thumbs but the four fingers load on the finger in question and on the adjacent fingers. 4. A single common factor for non-additive genetic variance produces a considerable improvement in the model. 5. The pattern of genetic effects differs between left and right hands. 6. Although the same model is appropriate for males and females, different parameters estimates are required. 7. The fit of models is sensitive to the scale of measurement.
DATE PUBLISHED
1982 Nov-Dec
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 1982/11/01
medline 1982/11/01 00:01
entrez 1982/11/01 00:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Martin NG Martin N G NG
Eaves LJ Eaves L J LJ
Loesch DZ Loesch D Z DZ
INVESTIGATORS
JOURNAL
VOLUME: 9
ISSUE: 6
TITLE: Annals of human biology
ISOABBREVIATION: Ann. Hum. Biol.
YEAR:
MONTH:
DAY:
MEDLINEDATE: 1982 Nov-Dec
SEASON:
CITEDMEDIUM: Print
ISSN: 0301-4460
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Ann Hum Biol
COUNTRY: England
ISSNLINKING: 0301-4460
NLMUNIQUEID: 0404024
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Analysis of Variance
Dermatoglyphics
Female
Genetics, Medical
Humans
Male
Models, Biological
Phenotype
Sex Factors
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's