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|
| PMID |
|
|
| TITLE |
|
| Inheritance and alcohol as factors influencing plasma uric acid levels. |
|
| ABSTRACT |
|
|
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| Variation in plasma uric acid levels in 206 pairs of male and female twins, aged from 18 to 34 years, was consistent with a simple model including only individual environmental and additive genetic effects and a heritability of h2 = 0.73. Individual environmental variation was estimated to be approximately the same as variation of individuals measured on two occasions. Correlations of DZ pairs were also consistent with sex-linked genetic effects. In men there was a significant genetic correlation with weekly alcohol consumption and as much as 18% of the variation in uric acid levels could be accounted for by genetic variation in alcohol consumption. |
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| DATE PUBLISHED |
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|
| HISTORY |
|
| PUBSTATUS |
PUBSTATUSDATE |
| pubmed |
1983/01/01 |
| medline |
1983/01/01 00:01 |
| entrez |
1983/01/01 00:00 |
|
| AUTHORS |
|
| NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
| Whitfield JB |
|
Whitfield |
J B |
JB |
|
|
| Martin NG |
|
Martin |
N G |
NG |
|
|
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| INVESTIGATORS |
|
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| JOURNAL |
|
| VOLUME: 32 |
| ISSUE: 2 |
| TITLE: Acta geneticae medicae et gemellologiae |
| ISOABBREVIATION: Acta Genet Med Gemellol (Roma) |
| YEAR: 1983 |
| MONTH: |
| DAY: |
| MEDLINEDATE: |
| SEASON: |
| CITEDMEDIUM: Print |
| ISSN: 0001-5660 |
| ISSNTYPE: Print |
|
| MEDLINE JOURNAL |
|
| MEDLINETA: Acta Genet Med Gemellol (Roma) |
| COUNTRY: Italy |
| ISSNLINKING: 0001-5660 |
| NLMUNIQUEID: 0370314 |
|
| PUBLICATION TYPE |
|
| PUBLICATIONTYPE TEXT |
| Journal Article |
| Research Support, Non-U.S. Gov't |
|
| COMMENTS AND CORRECTIONS |
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|
| GRANTS |
|
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| GENERAL NOTE |
|
|
| KEYWORDS |
|
|
| MESH HEADINGS |
|
| DESCRIPTORNAME |
QUALIFIERNAME |
| Adolescent |
|
| Adult |
|
| Alcohol Drinking |
|
| Environment |
|
| Female |
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| Genetic Linkage |
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| Genetic Variation |
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| Humans |
|
| Male |
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| Models, Genetic |
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| Pregnancy |
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| Twins, Dizygotic |
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| Twins, Monozygotic |
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| Uric Acid |
blood |
|
| SUPPLEMENTARY MESH |
|
|
| GENE SYMBOLS |
|
|
| CHEMICALS |
|
| REGISTRYNUMBER |
NAMEOFSUBSTANCE |
| 268B43MJ25 |
Uric Acid |
|
| OTHER ID's |
|
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|
