Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
6606608
TITLE
Association between alpha-1-antitrypsin types and the common cold.
ABSTRACT
Associations have been found between self-reported cold symptoms and Pi type in 84 pairs of identical twins. The risk of cold symptoms relative to MM phenotypes was 1.2 times greater in MS and 2.5 times greater in MZ individuals. Up to 9% of variance in cold symptoms could be attributed to Pi type, representing at least 20% of the total genetical variance.
DATE PUBLISHED
1983
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 1983/01/01
medline 1983/01/01 00:01
entrez 1983/01/01 00:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Martin NG Martin N G NG
Oakeshott JG Oakeshott J G JG
Clark P Clark P P
Carr A Carr A A
INVESTIGATORS
JOURNAL
VOLUME: 33
ISSUE: 5
TITLE: Human heredity
ISOABBREVIATION: Hum. Hered.
YEAR: 1983
MONTH:
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0001-5652
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Hum Hered
COUNTRY: Switzerland
ISSNLINKING: 0001-5652
NLMUNIQUEID: 0200525
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Common Cold physiopathology
Female physiopathology
Humans physiopathology
Pregnancy physiopathology
Twins, Monozygotic physiopathology
alpha 1-Antitrypsin genetics
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
REGISTRYNUMBER NAMEOFSUBSTANCE
0 alpha 1-Antitrypsin
OTHER ID's