|
|
| PMID |
|
|
| TITLE |
|
| Genomic meta-analyses of binge-eating behavior and anorexia nervosa yield insights into the unique and shared biology of eating disorder phenotypes. |
|
| ABSTRACT |
|
|
|
| Eating disorders-including anorexia nervosa (AN), bulimia nervosa and binge-eating disorder-are clinically distinct but exhibit symptom overlap and diagnostic crossover. Genomic analyses have mostly examined AN. Here we conducted a genomic meta-analysis of case-control studies of binge-eating behavior (BE; 39,279 cases, 1,227,436 controls), alongside analyses of AN (24,223 cases, 1,243,971 controls) and its subtypes (all European ancestries). We identified six BE-associated loci, including loci associated with a higher body mass index and impulse-control behaviors. AN genome-wide association studies yielded eight loci, validating six loci. Subsequent polygenic risk score analysis demonstrated an association with AN in two East Asian ancestry studies. BE and AN exhibited similar positive genetic correlations with psychiatric disorders but opposing genetic correlations with anthropometric traits. Most of the genetic signal in BE and AN was not shared with body mass index. We have extended eating disorder genomics beyond AN; future work will incorporate multiple diagnoses and global ancestries. |
| © The Author(s) 2026. |
|
| DATE PUBLISHED |
|
|
| HISTORY |
|
| PUBSTATUS |
PUBSTATUSDATE |
| received |
2025/11/06 |
| accepted |
2026/06/29 |
| medline |
2026/09/10 11:55 |
| pubmed |
2026/09/10 11:54 |
| entrez |
2026/09/10 06:36 |
| pmc-release |
2026/08/19 |
|
| AUTHORS |
|
| NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
| Termorshuizen JD |
|
Termorshuizen |
Jet D |
JD |
|
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. |
| Davies HL |
|
Davies |
Helena L |
HL |
|
Institute of Biological Psychiatry, Mental Health Center Sct. Hans, Mental Health Services Copenhagen, Roskilde, Denmark. |
| Lee SH |
|
Lee |
Sang-Hyuck |
SH |
|
National Institute for Health Research Biomedical Research Centre, King's College London and South London and Maudsley National Health Service Trust, London, UK. |
| Dennis JK |
|
Dennis |
Jessica K |
JK |
|
Graduate Program in Bioinformatics, University of British Columbia, Vancouver, British Columbia Canada. |
| Hübel C |
|
Hübel |
Christopher |
C |
|
Clinic for Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, German Red Cross Hospitals Berlin, Berlin, Germany. |
| Johnson JS |
|
Johnson |
Jessica S |
JS |
|
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC USA. |
| Lu Y |
|
Lu |
Yi |
Y |
|
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. |
| Munn-Chernoff MA |
|
Munn-Chernoff |
Melissa A |
MA |
|
Department of Community, Family and Addiction Sciences, Texas Tech University, Lubbock, TX USA. |
| Peters T |
|
Peters |
Triinu |
T |
|
Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. |
| Qi B |
|
Qi |
Baiyu |
B |
|
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC USA. |
| Schaumberg KE |
|
Schaumberg |
Katherine E |
KE |
|
Department of Psychology, University of Texas, Austin, TX USA. |
| Signer RH |
|
Signer |
Rebecca H |
RH |
|
Department of Psychiatry, Yale University, New Haven, CT USA. |
| Singh K |
|
Singh |
Karanvir |
K |
|
Graduate Program in Bioinformatics, University of British Columbia, Vancouver, British Columbia Canada. |
| Ter Kuile AR |
|
Ter Kuile |
Abigail R |
AR |
|
Department of Clinical, Educational and Health Psychology, University College London, London, UK. |
| Thornton LM |
|
Thornton |
Laura M |
LM |
|
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC USA. |
| Xu J |
|
Xu |
Jiayi |
J |
|
Department of Psychiatry, Yale University, New Haven, CT USA. |
| Yao S |
|
Yao |
Shuyang |
S |
|
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. |
| Yilmaz Z |
|
Yilmaz |
Zeynep |
Z |
|
Department of Biomedicine, Aarhus University, Aarhus, Denmark. |
| Zhang R |
|
Zhang |
Ruyue |
R |
|
Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC USA. |
| Zvrskovec J |
|
Zvrskovec |
Johan |
J |
|
National Institute for Health Research Biomedical Research Centre, King's College London and South London and Maudsley National Health Service Trust, London, UK. |
| Abdulkadir M |
|
Abdulkadir |
Mohamed |
M |
|
National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark. |
| Ayorech Z |
|
Ayorech |
Ziada |
Z |
|
Department of Psychology, PROMENTA Research Centre, University of Oslo, Oslo, Norway. |
| Corfield EC |
|
Corfield |
Elizabeth C |
EC |
|
MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. |
| Havdahl A |
|
Havdahl |
Alexandra |
A |
|
Psychiatric Genetic Epidemiology Group, Research Department, Lovisenberg Diakonale Hospital, Oslo, Norway. |
| Krebs K |
|
Krebs |
Kristi |
K |
|
Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia. |
| Mack TM |
|
Mack |
Taralynn M |
TM |
|
Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN USA. |
| Niarchou M |
|
Niarchou |
Maria |
M |
|
Department of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN USA. |
| Palviainen T |
|
Palviainen |
Teemu |
T |
|
Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland. |
| Sealock JM |
|
Sealock |
Julia M |
JM |
|
Stanley Center for Psychiatric Research, Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, MA USA. |
| Baker JH |
|
Baker |
Jessica H |
JH |
|
Independent Researcher, Mebane, NC USA. |
| Bergen AW |
|
Bergen |
Andrew W |
AW |
|
Department of Medicine, New Jersey Medical School, Rutgers University, Newark, NJ USA. |
| Birgegård A |
|
Birgegård |
Andreas |
A |
|
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. |
| Boraska Perica V |
|
Boraska Perica |
Vesna |
V |
|
Department for Medical Biology, University of Split School of Medicine, Split, Croatia. |
| Bühren K |
|
Bühren |
Katharina |
K |
|
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Ludwig-Maximilians-Universität München, Munich, Germany. |
| Burghardt R |
|
Burghardt |
Roland |
R |
|
Department of Child and Adolescent Psychiatry, Oberberg Fachklinik Fasanenkiez Berlin, Berlin, Germany. |
| Cassina M |
|
Cassina |
Matteo |
M |
|
Department of Women's and Children's Health, University of Padova, Padova, Italy. |
| Castellini G |
|
Castellini |
Giovanni |
G |
|
Department of Health Sciences, University of Florence, Florence, Italy. |
| Collantoni E |
|
Collantoni |
Enrico |
E |
|
Department of Neuroscience, University of Padova, Padova, Italy. |
| Crowley JJ |
|
Crowley |
James J |
JJ |
|
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. |
| Danner UN |
|
Danner |
Unna N |
UN |
|
Altrecht Eating Disorders Rintveld, Altrecht Mental Health Institute, Utrecht, the Netherlands. |
| Degenhardt F |
|
Degenhardt |
Franziska |
F |
|
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LVR University Hospital Essen, University of Duisburg-Essen, Essen, Germany. |
| DeSocio JE |
|
DeSocio |
Janiece E |
JE |
|
College of Nursing, Seattle University, Seattle, WA USA. |
| Dina C |
|
Dina |
Christian |
C |
|
Nantes Université, CNRS, INSERM, L'Institut du Thorax, Nantes, France. |
| Dmitrzak-Węglarz M |
|
Dmitrzak-Węglarz |
Monika |
M |
|
Department of Psychiatric Genetics, Medical Biology Center, Poznan University of Medical Sciences, Poznan, Poland. |
| Duncan LE |
|
Duncan |
Laramie E |
LE |
|
Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA USA. |
| Egberts KM |
|
Egberts |
Karin M |
KM |
|
Department of Child and Adolescent Psychiatry Herlaarhof, Reinier van Arkel, s-Hertogenbosch, Northern Brabant, the Netherlands. |
| Foretova L |
|
Foretova |
Lenka |
L |
|
Center of Medical Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic. |
| Giegling I |
|
Giegling |
Ina |
I |
|
Department of Psychiatry and Psychotherapy, Comprehensive Center for Clinical Neurosciences and Mental Health (C3NMH), Medical University of Vienna, Vienna, Austria. |
| Gonidakis F |
|
Gonidakis |
Fragiskos |
F |
|
First Department of Psychiatry, National and Kappodistrian University of Athens, Athens, Greece. |
| Gordon SD |
|
Gordon |
Scott D |
SD |
|
Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland Australia. |
| Grove J |
|
Grove |
Jakob |
J |
|
BiRC - Section for Bioinformatics and Computational Biology, Aarhus University, Aarhus, Denmark. |
| Guillaume S |
|
Guillaume |
Sébastien |
S |
|
Department of Emergency and Post-Emergency Psychiatry, CHU, University of Montpellier, Montpellier, France. |
| Guintivano JD |
|
Guintivano |
Jerry D |
JD |
|
Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC USA. |
| Hartmann AM |
|
Hartmann |
Annette M |
AM |
|
Department of Psychiatry and Psychotherapy, Comprehensive Center for Clinical Neurosciences and Mental Health (C3NMH), Medical University of Vienna, Vienna, Austria. |
| Hatzikotoulas K |
|
Hatzikotoulas |
Konstantinos |
K |
|
Helmholtz Zentrum München - German Research Centre for Environmental Health, Institute of Translational Genomics, Neuherberg, Germany. |
| Herms S |
|
Herms |
Stefan |
S |
|
Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany. |
| Imgart H |
|
Imgart |
Hartmut |
H |
|
Eating Disorders Unit, Parkland-Klinik, Bad Wildungen, Germany. |
| Jiménez-Murcia S |
|
Jiménez-Murcia |
Susana |
S |
|
Centre for Psychological Services, University of Barcelona, Barcelona, Spain. |
| Julià A |
|
Julià |
Antonio |
A |
|
Rheumatology Research Group, Vall d'Hebron Research Institute, Barcelona, Spain. |
| Kalsi G |
|
Kalsi |
Gursharan |
G |
|
Institute of Psychiatry, Psychology and Neuroscience, Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK. |
| Kaminská D |
|
Kaminská |
Deborah |
D |
|
Department of Psychiatry, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic. |
| Karhunen LJ |
|
Karhunen |
Leila J |
LJ |
|
Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland. |
| Kennedy HL |
|
Kennedy |
Hannah L |
HL |
|
Department of Psychological Medicine, University of Otago, Christchurch, New Zealand. |
| Kiezebrink KM |
|
Kiezebrink |
Kirsty M |
KM |
|
Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK. |
| Kolb T |
|
Kolb |
Theresa |
T |
|
Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. |
| Larsen JT |
|
Larsen |
Janne T |
JT |
|
The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus University, Aarhus, Denmark. |
| Li D |
|
Li |
Dong |
D |
|
Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA USA. |
| Lilenfeld L |
|
Lilenfeld |
Lisa |
L |
|
College of Clinical Psychology , The Chicago School, Washington, DC USA. |
| Maj M |
|
Maj |
Mario |
M |
|
Department of Psychiatry, University of Campania 'Luigi Vanvitelli', Naples, Italy. |
| Mattingsdal M |
|
Mattingsdal |
Morten |
M |
|
Division of Mental Health and Addiction, NORMENT KG Jebsen Centre, Oslo University Hospital, Oslo, Norway. |
| Meneguzzo P |
|
Meneguzzo |
Paolo |
P |
|
Padova Neuroscience Center, University of Padova, Padova, Italy. |
| Miller AL |
|
Miller |
Allison L |
AL |
|
Department of Pathology and Molecular Medicine, University of Otago, Christchurch, New Zealand. |
| Mitchell KS |
|
Mitchell |
Karen S |
KS |
|
Department of Psychiatry, Boston University Chobanian and Avedisian School of Medicine, Boston, MA USA. |
| Monteleone AM |
|
Monteleone |
Alessio Maria |
AM |
|
Department of Psychiatry, University of Campania 'Luigi Vanvitelli', Naples, Italy. |
| Olsen CM |
|
Olsen |
Catherine M |
CM |
|
Department of Population Health, QIMR Berghofer Medical Research Institute, Brisbane, Queensland Australia. |
| Padyukov L |
|
Padyukov |
Leonid |
L |
|
Department of Medicine Solna, Division of Rheumatology, Karolinska Institutet, Stockholm, Sweden. |
| Parker R |
|
Parker |
Richard |
R |
|
Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland Australia. |
| Pettie MA |
|
Pettie |
Michaela A |
MA |
|
Department of Pathology and Molecular Medicine, University of Otago, Christchurch, New Zealand. |
| Pinto D |
|
Pinto |
Dalila |
D |
|
Department of Genetics and Genomic Sciences, Mindich Child Health and Development Institute, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY USA. |
| Raevuori A |
|
Raevuori |
Anu |
A |
|
Department of Public Health, University of Helsinki, Helsinki, Finland. |
| Ripatti S |
|
Ripatti |
Samuli |
S |
|
Department of Public Health, University of Helsinki, Helsinki, Finland. |
| Roberts ME |
|
Roberts |
Marion E |
ME |
|
Department of General Practice and Primary Healthcare, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand. |
| Santonastaso P |
|
Santonastaso |
Paolo |
P |
|
Department of Neuroscience, University of Padova, Padova, Italy. |
| Savva A |
|
Savva |
Androula |
A |
|
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. |
| Schmidt UH |
|
Schmidt |
Ulrike H |
UH |
|
Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. |
| Schosser A |
|
Schosser |
Alexandra |
A |
|
Faculty of Medicine, Sigmund Freud University, Vienna, Austria. |
| Seitz J |
|
Seitz |
Jochen |
J |
|
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LVR University Hospital Essen, University of Duisburg-Essen, Essen, Germany. |
| Slachtova LL |
|
Slachtova |
Lenka Ls |
LL |
|
Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Prague, Czech Republic. |
| Slopien A |
|
Slopien |
Agnieszka |
A |
|
Department of Child and Adolescent Psychiatry, Poznan University of Medical Sciences, Poznan, Poland. |
| Sorbi S |
|
Sorbi |
Sandro |
S |
|
Department of Neuroscience, Psychology, Drug Research and Child Health (NEUROFARBA), University of Florence, Florence, Italy. |
| Straub PS |
|
Straub |
Peter S |
PS |
|
Department of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN USA. |
| Szatkiewicz JP |
|
Szatkiewicz |
Jin P |
JP |
|
Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC USA. |
| Tam FI |
|
Tam |
Friederike I |
FI |
|
Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany. |
| Tenconi E |
|
Tenconi |
Elena |
E |
|
Padova Neuroscience Center, University of Padova, Padova, Italy. |
| Tortorella A |
|
Tortorella |
Alfonso |
A |
|
Department of Psychiatry, University of Perugia, Perugia, Italy. |
| Tsitsika A |
|
Tsitsika |
Artemis |
A |
|
Adolescent Health Unit, Second Department of Pediatrics, 'P. & A. Kyriakou' Children's Hospital, National and Kappodistrian University of Athens, Athens, Greece. |
| van Elburg AA |
|
van Elburg |
Annemarie A |
AA |
|
Department of Clinical Psychology, Faculty for Social Sciences, Utrecht University, Utrecht, the Netherlands. |
| Wagner G |
|
Wagner |
Gudrun |
G |
|
Eating Disorders Unit, Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria. |
| Watson HJ |
|
Watson |
Hunna J |
HJ |
|
Discipline of Psychology, Curtin University, Perth, Western Australia Australia. |
| Adan RA |
|
Adan |
Roger Ah |
RA |
|
Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden. |
| Alfredsson L |
|
Alfredsson |
Lars |
L |
|
Centre for Occupational and Environmental Medicine, Stockholm, Sweden. |
| Andreassen OA |
|
Andreassen |
Ole A |
OA |
|
KG Jebsen Centre for Neurodevelopmental Disorders Research, University of Oslo, Oslo, Norway. |
| Ask H |
|
Ask |
Helga |
H |
|
PsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway. |
| Børglum AD |
|
Børglum |
Anders D |
AD |
|
Center for Genomics and Personalized Medicine, Aarhus University, Aarhus, Denmark. |
| Brandt HA |
|
Brandt |
Harry A |
HA |
|
Department of Psychiatry, ERC Pathlight, University of Maryland, St. Joseph Medical Center, Baltimore, MD USA. |
| Collier D |
|
Collier |
David |
D |
|
Institute of Psychiatry, Psychology and Neuroscience, Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK. |
| Crawford S |
|
Crawford |
Steven |
S |
|
Department of Psychiatry, ERC Pathlight, University of Maryland, St. Joseph Medical Center, Baltimore, MD USA. |
| Crow S |
|
Crow |
Scott |
S |
|
Department of Psychiatry, University of Minnesota, Minneapolis, MN USA. |
| Davis LK |
|
Davis |
Lea K |
LK |
|
Associate Faculty, New York Genome Center, New York, NY USA. |
| de Zwaan M |
|
de Zwaan |
Martina |
M |
|
Department of Psychosomatic Medicine and Psychotherapy, Hannover Medical School, Hannover, Germany. |
| Dedoussis G |
|
Dedoussis |
George |
G |
|
Department of Nutrition and Dietetics, Harokopio University, Athens, Greece. |
| Dick DM |
|
Dick |
Danielle M |
DM |
|
Department of Psychiatry, Rutgers University, Piscataway, NJ USA. |
| Ehrlich S |
|
Ehrlich |
Stefan |
S |
|
Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany. |
| Estivill X |
|
Estivill |
Xavier |
X |
|
Research Department, Quantitative Genomics Laboratories (qGenomics), Barcelona, Spain. |
| Favaro A |
|
Favaro |
Angela |
A |
|
Padova Neuroscience Center, University of Padova, Padova, Italy. |
| Fernández-Aranda F |
|
Fernández-Aranda |
Fernando |
F |
|
Psychoneurobiology of Eating and Addictive Behaviors Research Group, Bellvitge Biomedical Research Institute (IDIBELL), Hospitalet del Llobregat, Barcelona, Spain. |
| Fischer K |
|
Fischer |
Krista |
K |
|
Institute of Mathematics and Statistics, University of Tartu, Tartu, Estonia. |
| Forstner AJ |
|
Forstner |
Andreas J |
AJ |
|
Centre for Human Genetics, University of Marburg, Marburg, Germany. |
| Gorwood P |
|
Gorwood |
Philip |
P |
|
Sainte-Anne Hospital (CMME), GHU Paris Psychiatrie et Neurosciences, Paris, France. |
| Hakonarson H |
|
Hakonarson |
Hakon |
H |
|
Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA USA. |
| Hebebrand J |
|
Hebebrand |
Johannes |
J |
|
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, LVR University Hospital Essen, University of Duisburg-Essen, Essen, Germany. |
| Herpertz-Dahlmann B |
|
Herpertz-Dahlmann |
Beate |
B |
|
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, RWTH Aachen University, Aachen, Germany. |
| Hinney A |
|
Hinney |
Anke |
A |
|
Institute of Sex and Gender-Sensitive Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. |
| Hudson JI |
|
Hudson |
James I |
JI |
|
Biological Psychiatry Laboratory, McLean Hospital, Harvard Medical School, Belmont, MA USA. |
| Johnson C |
|
Johnson |
Craig |
C |
|
Eating Recovery Center, Denver, CO USA. |
| Jordan J |
|
Jordan |
Jennifer |
J |
|
Specialist Mental Health Clinical Research Unit, Health New Zealand Canterbury, Christchurch, New Zealand. |
| Kaplan AS |
|
Kaplan |
Allan S |
AS |
|
Department of Psychiatry, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario Canada. |
| Kaprio J |
|
Kaprio |
Jaakko |
J |
|
Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland. |
| Karwautz AF |
|
Karwautz |
Andreas Fk |
AF |
|
Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria. |
| Kas MJ |
|
Kas |
Martien Jh |
MJ |
|
Groningen Institute for Evolutionary Life Sciences, University of Groningen, Groningen, the Netherlands. |
| Kaye WH |
|
Kaye |
Walter H |
WH |
|
Department of Psychiatry, University of California, San Diego, San Diego, CA USA. |
| Kennedy JL |
|
Kennedy |
James L |
JL |
|
Tanenbaum Centre, Centre for Addiction and Mental Health, Toronto, Ontario Canada. |
| Kennedy MA |
|
Kennedy |
Martin A |
MA |
|
Department of Pathology and Molecular Medicine, University of Otago, Christchurch, New Zealand. |
| Keski-Rahkonen A |
|
Keski-Rahkonen |
Anna |
A |
|
Department of Public Health, University of Helsinki, Helsinki, Finland. |
| Kim YR |
|
Kim |
Youl-Ri |
YR |
|
Department of Psychiatry, Ilsan Paik Hospital, Inje University, Goyang, Republic of Korea. |
| Klump KL |
|
Klump |
Kelly L |
KL |
|
Department of Psychology, Michigan State University, East Lansing, MI USA. |
| Landén M |
|
Landén |
Mikael |
M |
|
Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden. |
| Le Hellard S |
|
Le Hellard |
Stéphanie |
S |
|
Department of Clinical Science, University of Bergen, Bergen, Norway. |
| Lehto K |
|
Lehto |
Kelli |
K |
|
Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia. |
| Li QS |
|
Li |
Qingqin S |
QS |
|
Human Genetics and Genomics, CHDI Management Inc., Princeton, NJ USA. |
| Lissowska J |
|
Lissowska |
Jolanta |
J |
|
Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland. |
| Luykx JJ |
|
Luykx |
Jurjen J |
JJ |
|
Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, the Netherlands. |
| Maguire SL |
|
Maguire |
Sarah L |
SL |
|
InsideOut Institute, University of Sydney, Sydney, New South Wales Australia. |
| Martin NG |
|
Martin |
Nicholas G |
NG |
|
Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland Australia. |
| Mattheisen M |
|
Mattheisen |
Manuel |
M |
|
Institute of Psychiatric Phenomics and Genomics, Ludwig-Maximilians-Universität München, Munich, Germany. |
| Medland SE |
|
Medland |
Sarah E |
SE |
|
School of Psychology and Counselling, Queensland University of Technology, Brisbane, Queensland Australia. |
| Mehler P |
|
Mehler |
Philip |
P |
|
University of Colorado School of Medicine, Aurora, CO USA. |
| Micali N |
|
Micali |
Nadia |
N |
|
Great Ormond Street Institute of Child Health, University College London, London, UK. |
| Mitchell JE |
|
Mitchell |
James E |
JE |
|
Department of Psychiatry and Behavioral Science, University of North Dakota, Fargo, ND USA. |
| Monteleone P |
|
Monteleone |
Palmiero |
P |
|
Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Salerno, Italy. |
| Mortensen PB |
|
Mortensen |
Preben Bo |
PB |
|
National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark. |
| Nacmias B |
|
Nacmias |
Benedetta |
B |
|
Department of Neuroscience, Psychology, Drug Research and Child Health (NEUROFARBA), University of Florence, Florence, Italy. |
| Ophoff RA |
|
Ophoff |
Roel A |
RA |
|
Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA USA. |
| Papezova H |
|
Papezova |
Hana |
H |
|
Department of Psychiatry, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic. |
| Pedersen NL |
|
Pedersen |
Nancy L |
NL |
|
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. |
| Petersen LV |
|
Petersen |
Liselotte V |
LV |
|
The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus University, Aarhus, Denmark. |
| Rajcsanyi LS |
|
Rajcsanyi |
Luisa S |
LS |
|
Institute of Sex and Gender-Sensitive Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. |
| Ramoz N |
|
Ramoz |
Nicolas |
N |
|
Université Paris Cité, Paris, France. |
| Reichborn-Kjennerud T |
|
Reichborn-Kjennerud |
Ted |
T |
|
Institute of Clinical Medicine, University of Oslo, Oslo, Norway. |
| Ricca V |
|
Ricca |
Valdo |
V |
|
Department of Health Sciences, University of Florence, Florence, Italy. |
| Ripke S |
|
Ripke |
Stephan |
S |
|
Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany. |
| Rujescu D |
|
Rujescu |
Dan |
D |
|
Department of Psychiatry and Psychotherapy, Comprehensive Center for Clinical Neurosciences and Mental Health (C3NMH), Medical University of Vienna, Vienna, Austria. |
| Rybakowski F |
|
Rybakowski |
Filip |
F |
|
Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland. |
| Scherer SW |
|
Scherer |
Stephen W |
SW |
|
McLaughlin Centre and Department of Molecular Genetics, University of Toronto, Toronto, Ontario Canada. |
| Slof-Op 't Landt MC |
|
Slof-Op 't Landt |
Margarita Ct |
MC |
|
Department of Psychiatry, Leiden University Medical Centre, Leiden, the Netherlands. |
| Steiger H |
|
Steiger |
Howard |
H |
|
Eating Disorders Continuum, Douglas Mental Health University Institute, Montreal, Quebec Canada. |
| Sullivan PF |
|
Sullivan |
Patrick F |
PF |
|
Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC USA. |
| Świątkowska B |
|
Świątkowska |
Beata |
B |
|
Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Lodz, Poland. |
| van Furth EF |
|
van Furth |
Eric F |
EF |
|
GGZ Rivierduinen Eating Disorders Ursula, Leiden, the Netherlands. |
| Wade TD |
|
Wade |
Tracey D |
TD |
|
Discipline of Psychology, Flinders Institute for Mental Health and Wellbeing, Adelaide, South Australia Australia. |
| Werge T |
|
Werge |
Thomas |
T |
|
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark. |
| Whiteman DC |
|
Whiteman |
David C |
DC |
|
Department of Population Health, QIMR Berghofer Medical Research Institute, Brisbane, Queensland Australia. |
| Woodside DB |
|
Woodside |
D Blake |
DB |
|
Department of Psychiatry, University of Toronto, Toronto, Ontario Canada. |
| Wu YK |
|
Wu |
Ya-Ke |
YK |
|
School of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, NC USA. |
| Zipfel S |
|
Zipfel |
Stephan |
S |
|
German Centre for Mental Health, University of Tübingen, Tübingen, Germany. |
|
Disorders Working Group of the Psychiatric Genomics Consortium |
|
|
|
|
|
|
Estonian Biobank (EstBB) |
|
|
|
|
|
| Bulik CM |
|
Bulik |
Cynthia M |
CM |
|
Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC USA. |
| Huckins LM |
|
Huckins |
Laura M |
LM |
|
Department of Psychiatry, Yale University, New Haven, CT USA. |
| Breen G |
|
Breen |
Gerome |
G |
|
National Institute for Health Research Biomedical Research Centre, King's College London and South London and Maudsley National Health Service Trust, London, UK. |
| Coleman JRI |
|
Coleman |
Jonathan R I |
JRI |
|
National Institute for Health Research Biomedical Research Centre, King's College London and South London and Maudsley National Health Service Trust, London, UK. |
|
Disorders Working Group of the Psychiatric Genomics Consortium |
|
|
|
|
|
|
| INVESTIGATORS |
|
| LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
| Termorshuizen |
Jet D |
JD |
|
| Davies |
Helena L |
HL |
|
| Lee |
Sang-Hyuck |
SH |
|
| Dennis |
Jessica K |
JK |
|
| Hübel |
Christopher |
C |
|
| Johnson |
Jessica S |
JS |
|
| Lu |
Yi |
Y |
|
| Munn-Chernoff |
Melissa A |
MA |
|
| Peters |
Triinu |
T |
|
| Qi |
Baiyu |
B |
|
| Schaumberg |
Katherine E |
KE |
|
| Signer |
Rebecca H |
RH |
|
| Singh |
Karanvir |
K |
|
| Thornton |
Laura M |
LM |
|
| Xu |
Jiayi |
J |
|
| Yao |
Shuyang |
S |
|
| Yilmaz |
Zeynep |
Z |
|
| Zhang |
Ruyue |
R |
|
| Zvrskovec |
Johan |
J |
|
| Abdulkadir |
Mohamed |
M |
|
| Ayorech |
Ziada |
Z |
|
| Corfield |
Elizabeth C |
EC |
|
| Havdahl |
Alexandra |
A |
|
| Krebs |
Kristi |
K |
|
| Mack |
Taralynn M |
TM |
|
| Niarchou |
Maria |
M |
|
| Palviainen |
Teemu |
T |
|
| Sealock |
Julia M |
JM |
|
| Baker |
Jessica H |
JH |
|
| Bergen |
Andrew W |
AW |
|
| Birgegård |
Andreas |
A |
|
| Boraska Perica |
Vesna |
V |
|
| Bühren |
Katharina |
K |
|
| Burghardt |
Roland |
R |
|
| Cassina |
Matteo |
M |
|
| Castellini |
Giovanni |
G |
|
| Collantoni |
Enrico |
E |
|
| Crowley |
James J |
JJ |
|
| Danner |
Unna N |
UN |
|
| Degenhardt |
Franziska |
F |
|
| DeSocio |
Janiece E |
JE |
|
| Dina |
Christian |
C |
|
| Dmitrzak-Węglarz |
Monika |
M |
|
| Duncan |
Laramie E |
LE |
|
| Egberts |
Karin M |
KM |
|
| Foretova |
Lenka |
L |
|
| Giegling |
Ina |
I |
|
| Gonidakis |
Fragiskos |
F |
|
| Gordon |
Scott D |
SD |
|
| Grove |
Jakob |
J |
|
| Guillaume |
Sébastien |
S |
|
| Guintivano |
Jerry D |
JD |
|
| Hartmann |
Annette M |
AM |
|
| Hatzikotoulas |
Konstantinos |
K |
|
| Herms |
Stefan |
S |
|
| Imgart |
Hartmut |
H |
|
| Jiménez-Murcia |
Susana |
S |
|
| Julià |
Antonio |
A |
|
| Kalsi |
Gursharan |
G |
|
| Kaminská |
Deborah |
D |
|
| Karhunen |
Leila J |
LJ |
|
| Kennedy |
Hannah L |
HL |
|
| Kiezebrink |
Kirsty M |
KM |
|
| Kolb |
Theresa |
T |
|
| Larsen |
Janne T |
JT |
|
| Li |
Dong |
D |
|
| Lilenfeld |
Lisa |
L |
|
| Maj |
Mario |
M |
|
| Mattingsdal |
Morten |
M |
|
| Meneguzzo |
Paolo |
P |
|
| Miller |
Allison L |
AL |
|
| Mitchell |
Karen S |
KS |
|
| Monteleone |
Alessio Maria |
AM |
|
| Olsen |
Catherine M |
CM |
|
| Padyukov |
Leonid |
L |
|
| Parker |
Richard |
R |
|
| Pettie |
Michaela A |
MA |
|
| Pinto |
Dalila |
D |
|
| Raevuori |
Anu |
A |
|
| Ripatti |
Samuli |
S |
|
| Roberts |
Marion E |
ME |
|
| Santonastaso |
Paolo |
P |
|
| Savva |
Androula |
A |
|
| Schmidt |
Ulrike H |
UH |
|
| Schosser |
Alexandra |
A |
|
| Seitz |
Jochen |
J |
|
| Slachtova |
Lenka Ls |
LL |
|
| Slopien |
Agnieszka |
A |
|
| Sorbi |
Sandro |
S |
|
| Straub |
Peter S |
PS |
|
| Szatkiewicz |
Jin P |
JP |
|
| Tam |
Friederike I |
FI |
|
| Tortorella |
Alfonso |
A |
|
| Tsitsika |
Artemis |
A |
|
| Wagner |
Gudrun |
G |
|
| Watson |
Hunna J |
HJ |
|
| Adan |
Roger Ah |
RA |
|
| Alfredsson |
Lars |
L |
|
| Andreassen |
Ole A |
OA |
|
| Ask |
Helga |
H |
|
| Børglum |
Anders D |
AD |
|
| Brandt |
Harry A |
HA |
|
| Collier |
David |
D |
|
| Crawford |
Steven |
S |
|
| Crow |
Scott |
S |
|
| Davis |
Lea K |
LK |
|
| Dedoussis |
George |
G |
|
| Dick |
Danielle M |
DM |
|
| Ehrlich |
Stefan |
S |
|
| Estivill |
Xavier |
X |
|
| Favaro |
Angela |
A |
|
| Fernández-Aranda |
Fernando |
F |
|
| Fischer |
Krista |
K |
|
| Forstner |
Andreas J |
AJ |
|
| Gorwood |
Philip |
P |
|
| Hakonarson |
Hakon |
H |
|
| Hebebrand |
Johannes |
J |
|
| Herpertz-Dahlmann |
Beate |
B |
|
| Hinney |
Anke |
A |
|
| Hudson |
James I |
JI |
|
| Johnson |
Craig |
C |
|
| Jordan |
Jennifer |
J |
|
| Kaplan |
Allan S |
AS |
|
| Kaprio |
Jaakko |
J |
|
| Karwautz |
Andreas Fk |
AF |
|
| Kas |
Martien Jh |
MJ |
|
| Kaye |
Walter H |
WH |
|
| Kennedy |
James L |
JL |
|
| Kennedy |
Martin A |
MA |
|
| Keski-Rahkonen |
Anna |
A |
|
| Kim |
Youl-Ri |
YR |
|
| Klump |
Kelly L |
KL |
|
| Landén |
Mikael |
M |
|
| Lehto |
Kelli |
K |
|
| Li |
Qingqin S |
QS |
|
| Lissowska |
Jolanta |
J |
|
| Luykx |
Jurjen J |
JJ |
|
| Maguire |
Sarah L |
SL |
|
| Martin |
Nicholas G |
NG |
|
| Mattheisen |
Manuel |
M |
|
| Medland |
Sarah E |
SE |
|
| Mehler |
Philip |
P |
|
| Micali |
Nadia |
N |
|
| Mitchell |
James E |
JE |
|
| Monteleone |
Palmiero |
P |
|
| Mortensen |
Preben Bo |
PB |
|
| Nacmias |
Benedetta |
B |
|
| Ophoff |
Roel A |
RA |
|
| Papezova |
Hana |
H |
|
| Pedersen |
Nancy L |
NL |
|
| Petersen |
Liselotte V |
LV |
|
| Rajcsanyi |
Luisa S |
LS |
|
| Ramoz |
Nicolas |
N |
|
| Reichborn-Kjennerud |
Ted |
T |
|
| Ricca |
Valdo |
V |
|
| Ripke |
Stephan |
S |
|
| Rujescu |
Dan |
D |
|
| Rybakowski |
Filip |
F |
|
| Scherer |
Stephen W |
SW |
|
| Slof-Op 't Landt |
Margarita Ct |
MC |
|
| Steiger |
Howard |
H |
|
| Sullivan |
Patrick F |
PF |
|
| Świątkowska |
Beata |
B |
|
| Wade |
Tracey D |
TD |
|
| Werge |
Thomas |
T |
|
| Whiteman |
David C |
DC |
|
| Woodside |
D Blake |
DB |
|
| Wu |
Ya-Ke |
YK |
|
| Zipfel |
Stephan |
S |
|
| Ter Kuile |
Abigail R |
AR |
|
| Tenconi |
Elena |
E |
|
| van Elburg |
Annemarie A |
AA |
|
| de Zwaan |
Martina |
M |
|
| Le Hellard |
Stéphanie |
S |
|
| van Furth |
Eric F |
EF |
|
| Bulik |
Cynthia M |
CM |
|
| Huckins |
Laura M |
LM |
|
| Breen |
Gerome |
G |
|
| Coleman |
Jonathan Ri |
JR |
|
|
| JOURNAL |
|
| VOLUME: 4 |
| ISSUE: 9 |
| TITLE: Nature. Mental health |
| ISOABBREVIATION: Nat Ment Health |
| YEAR: 2026 |
| MONTH: |
| DAY: |
| MEDLINEDATE: |
| SEASON: |
| CITEDMEDIUM: Internet |
| ISSN: 2731-6076 |
| ISSNTYPE: Electronic |
|
| MEDLINE JOURNAL |
|
|
| PUBLICATION TYPE |
|
| PUBLICATIONTYPE TEXT |
| Journal Article |
|
| COMMENTS AND CORRECTIONS |
|
| REFTYPE |
REFSOURCE |
REFPMID |
NOTE |
| UpdateOf |
medRxiv. 2025 May 08:2025.01.31.25321397. doi: 10.1101/2025.01.31.25321397. |
40385383 |
|
|
| GRANTS |
|
| GRANTID |
AGENCY |
COUNTRY |
| K01 MH123914 |
NIMH NIH HHS |
United States |
| R01 MH136149 |
NIMH NIH HHS |
United States |
| R01 MH119084 |
NIMH NIH HHS |
United States |
| R01 DA044014 |
NIDA NIH HHS |
United States |
| K01 MH116413 |
NIMH NIH HHS |
United States |
| R01 HD047186 |
NICHD NIH HHS |
United States |
| R01 MH118233 |
NIMH NIH HHS |
United States |
| R01 MH087786 |
NIMH NIH HHS |
United States |
| R01 MH134039 |
NIMH NIH HHS |
United States |
| R01 MH118278 |
NIMH NIH HHS |
United States |
| R01 DA050495 |
NIDA NIH HHS |
United States |
| R01 MH120170 |
NIMH NIH HHS |
United States |
| R56 MH129437 |
NIMH NIH HHS |
United States |
| R01 MH124871 |
NIMH NIH HHS |
United States |
| R01 MH124839 |
NIMH NIH HHS |
United States |
|
Wellcome Trust |
United Kingdom |
| R01 ES033630 |
NIEHS NIH HHS |
United States |
|
| GENERAL NOTE |
|
|
| KEYWORDS |
|
| KEYWORD |
| Behavioural genetics |
| Genome-wide association studies |
| Genomics |
| Psychiatric disorders |
|
| MESH HEADINGS |
|
|
| SUPPLEMENTARY MESH |
|
|
| GENE SYMBOLS |
|
|
| CHEMICALS |
|
|
| OTHER ID's |
|
|
|