Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
QIMR Home Page
GenEpi Home Page
About GenEpi
Publications
Contacts
Research
Staff Index
Collaborators
Software Tools
Computing Resources
Studies
Search
GenEpi Intranet
PMID
38233393
TITLE
X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements.
ABSTRACT
X-chromosomal genetic variants are understudied but can yield valuable insights into sexually dimorphic human traits and diseases. We performed a sex-stratified cross-ancestry X-chromosome-wide association meta-analysis of seven kidney-related traits (n = 908,697), identifying 23 loci genome-wide significantly associated with two of the traits: 7 for uric acid and 16 for estimated glomerular filtration rate (eGFR), including four novel eGFR loci containing the functionally plausible prioritized genes ACSL4, CLDN2, TSPAN6 and the female-specific DRP2. Further, we identified five novel sex-interactions, comprising male-specific effects at FAM9B and AR/EDA2R, and three sex-differential findings with larger genetic effect sizes in males at DCAF12L1 and MST4 and larger effect sizes in females at HPRT1. All prioritized genes in loci showing significant sex-interactions were located next to androgen response elements (ARE). Five ARE genes showed sex-differential expressions. This study contributes new insights into sex-dimorphisms of kidney traits along with new prioritized gene targets for further molecular research.
© 2024. The Author(s).
DATE PUBLISHED
2024 Jan 18
HISTORY
PUBSTATUS PUBSTATUSDATE
received 2023/05/01
accepted 2023/12/30
medline 2024/01/19 06:42
pubmed 2024/01/18 00:42
entrez 2024/01/17 23:14
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Scholz M Scholz Markus M LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany. markus.scholz@imise.uni-leipzig.de.
Horn K Horn Katrin K LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Pott J Pott Janne J LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Wuttke M Wuttke Matthias M Department of Medicine IV - Nephrology and Primary Care, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Kühnapfel A Kühnapfel Andreas A LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Nasr MK Nasr M Kamal MK Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.
Kirsten H Kirsten Holger H LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Li Y Li Yong Y Institute of Genetic Epidemiology, Department of Data Driven Medicine, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.
Hoppmann A Hoppmann Anselm A Institute of Genetic Epidemiology, Department of Data Driven Medicine, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.
Gorski M Gorski Mathias M Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.
Ghasemi S Ghasemi Sahar S DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.
Li M Li Man M Division of Nephrology and Hypertension, Department of Medicine, University of Utah, Salt Lake City, UT, USA.
Tin A Tin Adrienne A Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
Chai JF Chai Jin-Fang JF Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Cocca M Cocca Massimiliano M Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.
Wang J Wang Judy J Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.
Nutile T Nutile Teresa T Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Naples, Italy.
Akiyama M Akiyama Masato M Department of Ocular Pathology and Imaging Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Åsvold BO Åsvold Bjørn Olav BO Department of Endocrinology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
Bansal N Bansal Nisha N Kidney Research Institute, University of Washington, Seattle, WA, USA.
Biggs ML Biggs Mary L ML Department of Biostatistics, University of Washington, Seattle, WA, USA.
Boutin T Boutin Thibaud T Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.
Brenner H Brenner Hermann H Network Aging Research, Heidelberg University, Heidelberg, Germany.
Brumpton B Brumpton Ben B Clinic of Thoracic and Occupational Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
Burkhardt R Burkhardt Ralph R Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Regensburg, Germany.
Cai J Cai Jianwen J Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Campbell A Campbell Archie A Centre for Genomic and Experimental Medicine, Institute of Genetics & Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.
Campbell H Campbell Harry H Centre for Global Health, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland.
Chalmers J Chalmers John J The George Institute for Global Health, University of New South Wales, Sydney, NSW, Australia.
Chasman DI Chasman Daniel I DI Harvard Medical School, Boston, MA, USA.
Chee ML Chee Miao Ling ML Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.
Chee ML Chee Miao Li ML Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.
Chen X Chen Xu X Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden.
Cheng CY Cheng Ching-Yu CY Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.
Cifkova R Cifkova Renata R Department of Medicine II, Charles University in Prague, First Faculty of Medicine, Prague, Czech Republic.
Daviglus M Daviglus Martha M Institute for Minority Health Research, University of Illinois at Chicago, Chicago, IL, USA.
Delgado G Delgado Graciela G Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany.
Dittrich K Dittrich Katalin K University Hospital for Children and Adolescents, Pediatric Research Unit, Medical Faculty, University Medical Center, University of Leipzig, Leipzig, Germany.
Edwards TL Edwards Todd L TL Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Endlich K Endlich Karlhans K Department of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany.
Michael Gaziano J Michael Gaziano J J Massachusetts Veterans Epidemiology Research and Information Center, VA Cooperative Studies Program, VA Boston Healthcare System, Boston, MA, USA.
Giri A Giri Ayush A Biomedical Laboratory Research and Development, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA.
Giulianini F Giulianini Franco F Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Gordon SD Gordon Scott D SD QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Gudbjartsson DF Gudbjartsson Daniel F DF Iceland School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
Hallan S Hallan Stein S Department of Nephrology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
Hamet P Hamet Pavel P Medpharmgene, Montreal, QC, Canada.
Hartman CA Hartman Catharina A CA Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE), Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Hayward C Hayward Caroline C Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.
Heid IM Heid Iris M IM Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.
Hellwege JN Hellwege Jacklyn N JN Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Holleczek B Holleczek Bernd B Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Holm H Holm Hilma H deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
Hutri-Kähönen N Hutri-Kähönen Nina N Tampere Centre for Skills Training and Simulation, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Hveem K Hveem Kristian K K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health, Norwegian University of Science and Technology, Trondheim, Norway.
Isermann B Isermann Berend B Institute for Laboratory Medicine, University of Leipzig, Leipzig, Germany.
Jonas JB Jonas Jost B JB Privatpraxis Prof Jonas und Dr Panda-Jonas, Heidelberg, Germany.
Joshi PK Joshi Peter K PK Centre for Global Health, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland.
Kamatani Y Kamatani Yoichiro Y Laboratory of Complex Trait Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.
Kanai M Kanai Masahiro M Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Kastarinen M Kastarinen Mika M Finnish Medicines Agency, Kuopio, Finland.
Khor CC Khor Chiea Chuen CC Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.
Kiess W Kiess Wieland W University Hospital for Children and Adolescents, Pediatric Research Unit, Medical Faculty, University Medical Center, University of Leipzig, Leipzig, Germany.
Kleber ME Kleber Marcus E ME SYNLAB MVZ Humangenetik Mannheim, Mannheim, Germany.
Körner A Körner Antje A Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany.
Kovacs P Kovacs Peter P Department of Medicine, University of Leipzig, Leipzig, Germany.
Krajcoviechova A Krajcoviechova Alena A Center for Cardiovascular Prevention, Charles University in Prague, First Faculty of Medicine and Thomayer University Hospital, Prague, Czech Republic.
Kramer H Kramer Holly H Division of Nephrology and Hypertension, Loyola University Chicago, Chicago, IL, USA.
Krämer BK Krämer Bernhard K BK Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany.
Kuokkanen M Kuokkanen Mikko M Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.
Kähönen M Kähönen Mika M Department of Clinical Physiology, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Lange LA Lange Leslie A LA Division of Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado Denver-Anschutz Medical Campus, Aurora, CO, USA.
Lash JP Lash James P JP Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA.
Lehtimäki T Lehtimäki Terho T Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Li H Li Hengtong H Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.
Lin BM Lin Bridget M BM Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Liu J Liu Jianjun J Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.
Loeffler M Loeffler Markus M LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Lyytikäinen LP Lyytikäinen Leo-Pekka LP Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Magnusson PKE Magnusson Patrik K E PKE Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden.
Martin NG Martin Nicholas G NG QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Matsuda K Matsuda Koichi K Laboratory of Clinical Genome Sequencing, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.
Milaneschi Y Milaneschi Yuri Y Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, Amsterdam UMC/Vrije Universiteit and GGZ inGeest, Amsterdam, the Netherlands.
Mishra PP Mishra Pashupati P PP Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Mononen N Mononen Nina N Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Montgomery GW Montgomery Grant W GW University of Queensland, Brisbane, QLD, Australia.
Mook-Kanamori DO Mook-Kanamori Dennis O DO Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands.
Mychaleckyj JC Mychaleckyj Josyf C JC Center for Public Health Genomics, University of Virginia, Charlottesville, Charlottesville, VA, USA.
März W März Winfried W Synlab Academy, Synlab Holding Deutschland GmbH, Augsburg, Germany.
Nauck M Nauck Matthias M Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
Nikus K Nikus Kjell K Department of Cardiology, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Nolte IM Nolte Ilja M IM Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Noordam R Noordam Raymond R Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.
Okada Y Okada Yukinori Y Department of Genome Informatics, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan.
Olafsson I Olafsson Isleifur I Department of Clinical Biochemistry, Landspitali University Hospital, Reykjavik, Iceland.
Oldehinkel AJ Oldehinkel Albertine J AJ Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE), Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Penninx BWJH Penninx Brenda W J H BWJH Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, Amsterdam UMC/Vrije Universiteit and GGZ inGeest, Amsterdam, the Netherlands.
Perola M Perola Markus M Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Pirastu N Pirastu Nicola N Biostatistics Unit - Population and Medical Genomics Programme, Genomics Research Centre, Human Technopole Palazzo Italia, Viale Rita Levi‑Montalcini, 1, 20157, Milan, Italy.
Polasek O Polasek Ozren O University of Split Medical School, Split, Croatia.
Porteous DJ Porteous David J DJ Centre for Genomic and Experimental Medicine, Institute of Genetics & Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.
Poulain T Poulain Tanja T University Hospital for Children and Adolescents, Pediatric Research Unit, Medical Faculty, University Medical Center, University of Leipzig, Leipzig, Germany.
Psaty BM Psaty Bruce M BM Cardiovascular Health Research Unit, Department of Medicine, Department of Epidemiology, Department of Health Systems and Population Health, University of Washington, Seattle, WA, USA.
Rabelink TJ Rabelink Ton J TJ Einthoven Laboratory of Experimental Vascular Research, Leiden University Medical Center, Leiden, the Netherlands.
Raffield LM Raffield Laura M LM Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.
Raitakari OT Raitakari Olli T OT Research Center of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.
Rasheed H Rasheed Humaira H Division of Medicine and Laboratory Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway.
Reilly DF Reilly Dermot F DF Janssen Pharmaceuticals Inc., Titusville, NJ, 08560, USA.
Rice KM Rice Kenneth M KM Department of Biostatistics, University of Washington, Seattle, WA, USA.
Richmond A Richmond Anne A Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.
Ridker PM Ridker Paul M PM Harvard Medical School, Boston, MA, USA.
Rotter JI Rotter Jerome I JI The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Rudan I Rudan Igor I Centre for Global Health, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland.
Sabanayagam C Sabanayagam Charumathi C Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.
Salomaa V Salomaa Veikko V Finnish Institute for Health and Welfare, Helsinki, Finland.
Schneiderman N Schneiderman Neil N Department of Psychology, University of Miami, Coral Gables, FL, USA.
Schöttker B Schöttker Ben B Network Aging Research, Heidelberg University, Heidelberg, Germany.
Sims M Sims Mario M Department of Social Medicine, Population and Public Health, University of California at Riverside School of Medicine, Riverside, CA, USA.
Snieder H Snieder Harold H Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Stark KJ Stark Klaus J KJ Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.
Stefansson K Stefansson Kari K Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Stocker H Stocker Hannah H Network Aging Research, Heidelberg University, Heidelberg, Germany.
Stumvoll M Stumvoll Michael M Department of Medicine, University of Leipzig, Leipzig, Germany.
Sulem P Sulem Patrick P deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
Sveinbjornsson G Sveinbjornsson Gardar G deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.
Svensson PO Svensson Per O PO Department of Cardiology, Södersjukhuset, Stockholm, Sweden.
Tai ES Tai E-Shyong ES Duke-NUS Medical School, Singapore, Singapore.
Taylor KD Taylor Kent D KD The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Tayo BO Tayo Bamidele O BO Department of Public Health Sciences, Loyola University Chicago, Maywood, IL, USA.
Teren A Teren Andrej A Department of Cardiology and Intensive Care Medicine, University Hospital OWL of Bielefeld University, Campus Klinikum Bielefeld, Teutoburger Straße 50, 33604, Bielefeld, Germany.
Tham YC Tham Yih-Chung YC Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.
Thiery J Thiery Joachim J Institute for Laboratory Medicine, University of Leipzig, Leipzig, Germany.
Thio CHL Thio Chris H L CHL Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Thomas LF Thomas Laurent F LF Clinic of Laboratory Medicine, St.Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
Tremblay J Tremblay Johanne J Montreal University Hospital Research Center, CHUM, Montréal, QC, Canada.
Tönjes A Tönjes Anke A Department of Medicine, University of Leipzig, Leipzig, Germany.
van der Most PJ van der Most Peter J PJ Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Vitart V Vitart Veronique V Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.
Völker U Völker Uwe U Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
Wang YX Wang Ya Xing YX Beijing Institute of Ophthalmology, Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Wang C Wang Chaolong C School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wei WB Wei Wen Bin WB Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Whitfield JB Whitfield John B JB QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Wild SH Wild Sarah H SH Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland.
Wilson JF Wilson James F JF Centre for Global Health, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland.
Winkler TW Winkler Thomas W TW Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.
Wong TY Wong Tien-Yin TY Tsinghua Medicine, Tsinghua University, Beijing, China.
Woodward M Woodward Mark M The George Institute for Global Health, School of Public Health, Imperial College London, London, UK.
Sim X Sim Xueling X Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Chu AY Chu Audrey Y AY Genetics, Merck & Co., Inc, Kenilworth, NJ, USA.
Feitosa MF Feitosa Mary F MF Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.
Thorsteinsdottir U Thorsteinsdottir Unnur U Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Hung AM Hung Adriana M AM Vanderbilt University Medical Center, Division of Nephrology & Hypertension, Nashville, TN, USA.
Teumer A Teumer Alexander A Department of Population Medicine and Lifestyle Diseases Prevention, Medical University of Bialystok, Bialystok, Poland.
Franceschini N Franceschini Nora N Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Parsa A Parsa Afshin A Division of Kidney, Urologic and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
Köttgen A Köttgen Anna A Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Schlosser P Schlosser Pascal P Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Pattaro C Pattaro Cristian C Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.
INVESTIGATORS
JOURNAL
VOLUME: 15
ISSUE: 1
TITLE: Nature communications
ISOABBREVIATION: Nat Commun
YEAR: 2024
MONTH: Jan
DAY: 18
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Internet
ISSN: 2041-1723
ISSNTYPE: Electronic
MEDLINE JOURNAL
MEDLINETA: Nat Commun
COUNTRY: England
ISSNLINKING: 2041-1723
NLMUNIQUEID: 101528555
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Meta-Analysis
Journal Article
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Humans
Male
Female
Androgens genetics
Genome-Wide Association Study genetics
Kidney genetics
Chromosomes, Human, X genetics
Response Elements genetics
Polymorphism, Single Nucleotide genetics
Genetic Predisposition to Disease genetics
Tetraspanins genetics
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
REGISTRYNUMBER NAMEOFSUBSTANCE
0 Androgens
0 TSPAN6 protein, human
0 Tetraspanins
OTHER ID's
Designed by: GenEpi IT
Maintained by: GenEpi IT
Feedback: webmaster
Copyright © 2007 QIMR
For more information Contact Us
epiit@qimr.edu.au
Last Modified: Oct 15 2007