Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
36101707
TITLE
An Epidemiologic, Longitudinal, and Discordant-Twin Study of the Association Between Gambling Disorder and Suicidal Behaviors.
ABSTRACT
Gambling disorder is associated with suicidal behaviors, but it is not clear whether the association is due to common etiologic factors or to gambling disorder being causally related to suicidality. This question was examined from epidemiologic, longitudinal, and discordant twin study perspectives. The results suggested that the causes of the association with disordered gambling differed for suicidal ideation, plan, and attempt, and differed for men and women. The association of suicidal thoughts with disordered gambling was non-causally explained by common genetic influences among women (but not men). Conversely, there was evidence consistent with a potentially causal influence of disordered gambling on suicide attempt among men (but not women), which might have been related to gambling-related financial problems. The use of monetary data to identify individuals experiencing financial harms associated with their gambling may represent a more practicable target for screening, intervention, and prevention and may reduce gambling-related financial crises, thereby warding off a potential gambling-related suicide attempt.
DATE PUBLISHED
2022 Sep
HISTORY
PUBSTATUS PUBSTATUSDATE
entrez 2022/09/14 01:56
pubmed 2022/09/15 06:00
medline 2022/09/15 06:01
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Slutske WS Slutske Wendy S WS University of Missouri, Columbia, MO, USA.
Davis CN Davis Christal N CN University of Missouri, Columbia, MO, USA.
Lynskey MT Lynskey Michael T MT King's College London Institute of Psychiatry, Psychology, & Neuroscience, London, UK.
Heath AC Heath Andrew C AC Washington University School of Medicine, St. Louis, MO, USA.
Martin NG Martin Nicholas G NG QIMR Berghofer, Brisbane, Queensland, Australia.
INVESTIGATORS
JOURNAL
VOLUME: 10
ISSUE: 5
TITLE: Clinical psychological science : a journal of the Association for Psychological Science
ISOABBREVIATION: Clin Psychol Sci
YEAR: 2022
MONTH: Sep
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 2167-7026
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Clin Psychol Sci
COUNTRY: United States
ISSNLINKING: 2167-7034
NLMUNIQUEID: 101601751
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
COMMENTS AND CORRECTIONS
GRANTS
GRANTID AGENCY COUNTRY
R01 MH066206 NIMH NIH HHS United States
R01 AA007728 NIAAA NIH HHS United States
R01 DA018267 NIDA NIH HHS United States
T32 AA013526 NIAAA NIH HHS United States
R37 AA007728 NIAAA NIH HHS United States
GENERAL NOTE
KEYWORDS
KEYWORD
discordant twins
gambling disorder
genetic
suicidal behaviors
MESH HEADINGS
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's