Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
33509317
TITLE
16Up: Outline of a Study Investigating Wellbeing and Information and Communication Technology Use in Adolescent Twins.
ABSTRACT
The '16Up' study conducted at the QIMR Berghofer Medical Research Institute from January 2014 to December 2018 aimed to examine the physical and mental health of young Australian twins aged 16-18 years (N = 876; 371 twin pairs and 18 triplet sets). Measurements included online questionnaires covering physical and mental health as well as information and communication technology (ICT) use, actigraphy, sleep diaries and hair samples to determine cortisol concentrations. Study participants generally rated themselves as being in good physical (79%) and mental (73%) health and reported lower rates of psychological distress and exposure to alcohol, tobacco products or other substances than previously reported for this age group in the Australian population. Daily or near-daily online activity was almost universal among study participants, with no differences noted between males and females in terms of frequency or duration of internet access. Patterns of ICT use in this sample indicated that the respondents were more likely to use online information sources for researching physical health issues than for mental health or substance use issues, and that they generally reported partial levels of satisfaction with the mental health information they found online. This suggests that internet-based mental health resources can be readily accessed by adolescent Australians, and their computer literacy augurs well for future access to online health resources. In combination with other data collected as part of the ongoing Brisbane Longitudinal Twin Study, the 16Up project provides a valuable resource for the longitudinal investigation of genetic and environmental contributions to phenotypic variation in a variety of human traits.
DATE PUBLISHED
2020 12
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 2021/01/30 06:00
medline 2021/01/30 06:00
entrez 2021/01/29 05:39
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Mitchell BL Mitchell Brittany L BL School of Biomedical Science Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.
Kirk KM Kirk Katherine M KM Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
McAloney K McAloney Kerrie K Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Wright MJ Wright Margaret J MJ Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.
Davenport TA Davenport Tracey A TA Brain and Mind Centre, The University of Sydney, Sydney, New South Wales, Australia.
Hermens DF Hermens Daniel F DF Thompson Institute, University of the Sunshine Coast, Birtinya, Queensland, Australia.
Scott JG Scott James G JG UQ Centre for Clinical Research, The University of Queensland, Brisbane, Queensland, Australia.
McGrath JJ McGrath John J JJ National Centre for Register-based Research, Aarhus University, Aarhus, Denmark.
Gillespie NA Gillespie Nathan A NA Virginia Institute for Psychiatric and Behavioral Genetics, Richmond, Virginia, USA.
Carpenter JS Carpenter Joanne S JS Brain and Mind Centre, The University of Sydney, Sydney, New South Wales, Australia.
O'Callaghan VS O'Callaghan Victoria S VS Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.
Medland S Medland Sarah S Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Christensen H Christensen Helen H Black Dog Institute, University of New South Wales, Sydney, New South Wales, Australia.
Martin NG Martin Nicholas G NG School of Biomedical Science Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.
Burns JM Burns Jane M JM Young and Well Cooperative Research Centre, Melbourne, Victoria, Australia.
Hickie IB Hickie Ian B IB Brain and Mind Centre, The University of Sydney, Sydney, New South Wales, Australia.
INVESTIGATORS
JOURNAL
VOLUME: 23
ISSUE: 6
TITLE: Twin research and human genetics : the official journal of the International Society for Twin Studies
ISOABBREVIATION: Twin Res Hum Genet
YEAR: 2020
MONTH: 12
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Internet
ISSN: 1832-4274
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Twin Res Hum Genet
COUNTRY: England
ISSNLINKING: 1832-4274
NLMUNIQUEID: 101244624
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, Non-U.S. Gov't
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
KEYWORD
Twins
adolescents
cohort study
genetics
longitudinal
mental health
technology
MESH HEADINGS
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's