|
|
| PMID |
|
|
| TITLE |
|
| Childhood aggression and the co-occurrence of behavioural and emotional problems: results across ages 3-16 years from multiple raters in six cohorts in the EU-ACTION project. |
|
| ABSTRACT |
|
|
|
| Childhood aggression and its resulting consequences inflict a huge burden on affected children, their relatives, teachers, peers and society as a whole. Aggression during childhood rarely occurs in isolation and is correlated with other symptoms of childhood psychopathology. In this paper, we aim to describe and improve the understanding of the co-occurrence of aggression with other forms of childhood psychopathology. We focus on the co-occurrence of aggression and other childhood behavioural and emotional problems, including other externalising problems, attention problems and anxiety-depression. The data were brought together within the EU-ACTION (Aggression in Children: unravelling gene-environment interplay to inform Treatment and InterventiON strategies) project. We analysed the co-occurrence of aggression and other childhood behavioural and emotional problems as a function of the child's age (ages 3 through 16 years), gender, the person rating the behaviour (father, mother or self) and assessment instrument. The data came from six large population-based European cohort studies from the Netherlands (2x), the UK, Finland and Sweden (2x). Multiple assessment instruments, including the Child Behaviour Checklist (CBCL), the Strengths and Difficulties Questionnaire (SDQ) and Multidimensional Peer Nomination Inventory (MPNI), were used. There was a good representation of boys and girls in each age category, with data for 30,523 3- to 4-year-olds (49.5% boys), 20,958 5- to 6-year-olds (49.6% boys), 18,291 7- to 8-year-olds (49.0% boys), 27,218 9- to 10-year-olds (49.4% boys), 18,543 12- to 13-year-olds (48.9% boys) and 10,088 15- to 16-year-olds (46.6% boys). We replicated the well-established gender differences in average aggression scores at most ages for parental ratings. The gender differences decreased with age and were not present for self-reports. Aggression co-occurred with the majority of other behavioural and social problems, from both externalising and internalising domains. At each age, the co-occurrence was particularly prevalent for aggression and oppositional and ADHD-related problems, with correlations of around 0.5 in general. Aggression also showed substantial associations with anxiety-depression and other internalizing symptoms (correlations around 0.4). Co-occurrence for self-reported problems was somewhat higher than for parental reports, but we found neither rater differences, nor differences across assessment instruments in co-occurrence patterns. There were large similarities in co-occurrence patterns across the different European countries. Finally, co-occurrence was generally stable across age and sex, and if any change was observed, it indicated stronger correlations when children grew older. We present an online tool to visualise these associations as a function of rater, gender, instrument and cohort. In addition, we present a description of the full EU-ACTION projects, its first results and the future perspectives. |
|
| DATE PUBLISHED |
|
|
| HISTORY |
|
| PUBSTATUS |
PUBSTATUSDATE |
| received |
2017/01/27 |
| accepted |
2018/05/16 |
| pubmed |
2018/05/31 06:00 |
| medline |
2018/10/10 06:00 |
| entrez |
2018/05/31 06:00 |
|
| AUTHORS |
|
| NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
| Bartels M |
|
Bartels |
Meike |
M |
|
Amsterdam Neuroscience, Amsterdam, The Netherlands. m.bartels@vu.nl. |
| Hendriks A |
|
Hendriks |
Anne |
A |
|
Amsterdam Public Health Research Institute, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. |
| Mauri M |
|
Mauri |
Matteo |
M |
|
University of Cagliari, Cagliari, Italy. |
| Krapohl E |
|
Krapohl |
Eva |
E |
|
Medical Research Council Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK. |
| Whipp A |
|
Whipp |
Alyce |
A |
|
Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland. |
| Bolhuis K |
|
Bolhuis |
Koen |
K |
|
Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands. |
| Conde LC |
|
Conde |
Lucia Colodro |
LC |
|
Psychiatric Genetics Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Australia. |
| Luningham J |
|
Luningham |
Justin |
J |
|
Department of Psychology, University of Notre Dame, Notre Dame, USA. |
| Fung Ip H |
|
Fung Ip |
Hill |
H |
|
Amsterdam Public Health Research Institute, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. |
| Hagenbeek F |
|
Hagenbeek |
Fiona |
F |
|
Amsterdam Public Health Research Institute, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. |
| Roetman P |
|
Roetman |
Peter |
P |
|
Curium-LUMC, Academic Centre of Child and Youth Psychiatry, Leiden University Medical Center, Leiden, The Netherlands. |
| Gatej R |
|
Gatej |
Raluca |
R |
|
Curium-LUMC, Academic Centre of Child and Youth Psychiatry, Leiden University Medical Center, Leiden, The Netherlands. |
| Lamers A |
|
Lamers |
Audri |
A |
|
Curium-LUMC, Academic Centre of Child and Youth Psychiatry, Leiden University Medical Center, Leiden, The Netherlands. |
| Nivard M |
|
Nivard |
Michel |
M |
|
Amsterdam Public Health Research Institute, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. |
| van Dongen J |
|
van Dongen |
Jenny |
J |
|
Amsterdam Public Health Research Institute, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. |
| Lu Y |
|
Lu |
Yi |
Y |
|
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. |
| Middeldorp C |
|
Middeldorp |
Christel |
C |
|
University of Queensland, Brisbane, Australia. |
| van Beijsterveldt T |
|
van Beijsterveldt |
Toos |
T |
|
Amsterdam Public Health Research Institute, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. |
| Vermeiren R |
|
Vermeiren |
Robert |
R |
|
VU Medical Centre, Amsterdam, The Netherlands. |
| Hankemeijer T |
|
Hankemeijer |
Thomas |
T |
|
Division of Analytical Biosciences, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands. |
| Kluft C |
|
Kluft |
Cees |
C |
|
Good Biomarker Sciences, Leiden, The Netherlands. |
| Medland S |
|
Medland |
Sarah |
S |
|
Psychiatric Genetics Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Australia. |
| Lundström S |
|
Lundström |
Sebastian |
S |
|
Centre for Ethics, Law and Mental Health (CELAM), University of Gothenburg, Gothenburg, Sweden. |
| Rose R |
|
Rose |
Richard |
R |
|
Department of Psychological & Brain Sciences, Indiana University, Bloomington, IN, USA. |
| Pulkkinen L |
|
Pulkkinen |
Lea |
L |
|
Department of Psychology, University of Jyvaskyla, Jyvaskyla, Finland. |
| Vuoksimaa E |
|
Vuoksimaa |
Eero |
E |
|
Department of Public Health, University of Helsinki, Helsinki, Finland. |
| Korhonen T |
|
Korhonen |
Tellervo |
T |
|
Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland. |
| Martin NG |
|
Martin |
Nicholas G |
NG |
|
QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia. |
| Lubke G |
|
Lubke |
Gitta |
G |
|
Department of Psychology, University of Notre Dame, Notre Dame, USA. |
| Finkenauer C |
|
Finkenauer |
Catrin |
C |
|
Youth Studies, Interdisciplinary Center, Utrecht University, Utrecht, The Netherlands. |
| Fanos V |
|
Fanos |
Vassilios |
V |
|
University of Cagliari, Cagliari, Italy. |
| Tiemeier H |
|
Tiemeier |
Henning |
H |
|
Department of Psychiatry, Erasmus Medical Center, Rotterdam, The Netherlands. |
| Lichtenstein P |
|
Lichtenstein |
Paul |
P |
|
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. |
| Plomin R |
|
Plomin |
Robert |
R |
|
Medical Research Council Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK. |
| Kaprio J |
|
Kaprio |
Jaakko |
J |
|
Department of Public Health, University of Helsinki, Helsinki, Finland. |
| Boomsma DI |
|
Boomsma |
Dorret I |
DI |
|
Amsterdam Neuroscience, Amsterdam, The Netherlands. |
|
| INVESTIGATORS |
|
|
| JOURNAL |
|
| VOLUME: 27 |
| ISSUE: 9 |
| TITLE: European child & adolescent psychiatry |
| ISOABBREVIATION: Eur Child Adolesc Psychiatry |
| YEAR: 2018 |
| MONTH: Sep |
| DAY: |
| MEDLINEDATE: |
| SEASON: |
| CITEDMEDIUM: Internet |
| ISSN: 1435-165X |
| ISSNTYPE: Electronic |
|
| MEDLINE JOURNAL |
|
| MEDLINETA: Eur Child Adolesc Psychiatry |
| COUNTRY: Germany |
| ISSNLINKING: 1018-8827 |
| NLMUNIQUEID: 9212296 |
|
| PUBLICATION TYPE |
|
| PUBLICATIONTYPE TEXT |
| Journal Article |
|
| COMMENTS AND CORRECTIONS |
|
|
| GRANTS |
|
| GRANTID |
AGENCY |
COUNTRY |
| CATSS |
the Söderström-Königska Foundation |
|
| 024.001.003 |
The Netherlands Organization for Scientific Research (NWO) |
|
| 016.VICI.170.200 |
The Netherlands Organization for Scientific Research (NWO-ZonMw) |
|
| 912-10-020 |
ZonMw |
|
| CATSS |
the Swedish Research Council |
|
| MR/M021475/1 |
UK Medical Research Council |
|
| 56-464-14192 |
Nederlandse Organisatie voor Wetenschappelijk Onderzoek |
|
| AA-09203 |
National Institute on Drug Abuse |
|
| 213506 |
Academy of Finland Center of Excellence Program |
|
| 205585 |
Academy of Finland |
|
| 463-06-001 |
Nederlandse Organisatie voor Wetenschappelijk Onderzoek |
|
| TCHAD |
the Swedish Research Council |
|
| TCHAD |
Forskningsrådet för Arbetsliv och Socialvetenskap (SE) |
|
| GenR |
Netherlands Organization for Health Research and Development (ZonMw) |
|
| R01 AA009203 |
NIAAA NIH HHS |
United States |
| 265240 |
Academy of Finland |
|
| 263278 |
Academy of Finland |
|
| G0901245 |
Medical Research Council |
United Kingdom |
| 602768 |
FP7/2007-2013 |
|
| 480-04-004 |
Nederlandse Organisatie voor Wetenschappelijk Onderzoek |
|
| 451-04-034 |
Nederlandse Organisatie voor Wetenschappelijk Onderzoek |
|
| G19/2 |
Medical Research Council |
United Kingdom |
| PAH/6635 |
Koninklijke Nederlandse Akademie van Wetenschappen |
|
| 129680 |
Academy of Finland Center of Excellence Program |
|
| 141054 |
Academy of Finland |
|
| 264146 |
Academy of Finland |
|
| MR/M021475/1 |
Medical Research Council |
United Kingdom |
| GenR |
Erasmus Medical Center, Rotterdam |
|
| 480-15-001/674 |
Nederlandse Organisatie voor Wetenschappelijk Onderzoek |
|
| K05 AA000145 |
NIAAA NIH HHS |
United States |
| R01 AA012502 |
NIAAA NIH HHS |
United States |
| 118555 |
Academy of Finland |
|
| G0500079 |
Medical Research Council |
United Kingdom |
| R01 DA018673 |
NIDA NIH HHS |
United States |
| AA-00145 |
National Institute on Drug Abuse |
|
| 201413 |
FP7-Heallth-F4-2007 |
|
| AA-12502 |
National Institute on Drug Abuse |
|
| 100499 |
Academy of Finland |
|
| CATSS |
Forskningsrådet för Arbetsliv och Socialvetenskap (SE) |
|
| R37 AA012502 |
NIAAA NIH HHS |
United States |
|
| GENERAL NOTE |
|
|
| KEYWORDS |
|
| KEYWORD |
| Aggression |
| Behavioural and emotional problems |
| Childhood |
| Co-occurence |
| Comorbidity |
|
| MESH HEADINGS |
|
| DESCRIPTORNAME |
QUALIFIERNAME |
| Adolescent |
|
| Affective Symptoms |
psychology |
| Aggression |
psychology |
| Child |
psychology |
| Child Behavior Disorders |
psychology |
| Child, Preschool |
psychology |
| Cohort Studies |
psychology |
| Female |
psychology |
| Humans |
psychology |
| Male |
psychology |
|
| SUPPLEMENTARY MESH |
|
|
| GENE SYMBOLS |
|
|
| CHEMICALS |
|
|
| OTHER ID's |
|
|
|
