Genetic Epidemiology, Psychiatric Genetics, Asthma Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
28975875
TITLE
Education in Twins and Their Parents Across Birth Cohorts Over 100 years: An Individual-Level Pooled Analysis of 42-Twin Cohorts.
ABSTRACT
Whether monozygotic (MZ) and dizygotic (DZ) twins differ from each other in a variety of phenotypes is important for genetic twin modeling and for inferences made from twin studies in general. We analyzed whether there were differences in individual, maternal and paternal education between MZ and DZ twins in a large pooled dataset. Information was gathered on individual education for 218,362 adult twins from 27 twin cohorts (53% females; 39% MZ twins), and on maternal and paternal education for 147,315 and 143,056 twins respectively, from 28 twin cohorts (52% females; 38% MZ twins). Together, we had information on individual or parental education from 42 twin cohorts representing 19 countries. The original education classifications were transformed to education years and analyzed using linear regression models. Overall, MZ males had 0.26 (95% CI [0.21, 0.31]) years and MZ females 0.17 (95% CI [0.12, 0.21]) years longer education than DZ twins. The zygosity difference became smaller in more recent birth cohorts for both males and females. Parental education was somewhat longer for fathers of DZ twins in cohorts born in 1990-1999 (0.16 years, 95% CI [0.08, 0.25]) and 2000 or later (0.11 years, 95% CI [0.00, 0.22]), compared with fathers of MZ twins. The results show that the years of both individual and parental education are largely similar in MZ and DZ twins. We suggest that the socio-economic differences between MZ and DZ twins are so small that inferences based upon genetic modeling of twin data are not affected.
DATE PUBLISHED
2017 Oct
HISTORY
PUBSTATUS PUBSTATUSDATE
entrez 2017/10/05 06:00
pubmed 2017/10/05 06:00
medline 2017/10/05 06:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Silventoinen K Silventoinen Karri K Department of Social Research,University of Helsinki,Helsinki,Finland.
Jelenkovic A Jelenkovic Aline A Department of Social Research,University of Helsinki,Helsinki,Finland.
Latvala A Latvala Antti A Institute for Molecular Medicine FIMM,Helsinki,Finland.
Sund R Sund Reijo R Department of Social Research,University of Helsinki,Helsinki,Finland.
Yokoyama Y Yokoyama Yoshie Y Department of Public Health Nursing,Osaka City University,Osaka,Japan.
Ullemar V Ullemar Vilhelmina V Department of Medical Epidemiology and Biostatistics,Karolinska Institutet,Stockholm,Sweden.
Almqvist C Almqvist Catarina C Department of Medical Epidemiology and Biostatistics,Karolinska Institutet,Stockholm,Sweden.
Derom CA Derom Catherine A CA Centre of Human Genetics,University Hospitals Leuven,Leuven,Belgium.
Vlietinck RF Vlietinck Robert F RF Centre of Human Genetics,University Hospitals Leuven,Leuven,Belgium.
Loos RJF Loos Ruth J F RJF The Charles Bronfman Institute for Personalized Medicine,The Mindich Child Health and Development Institute,Icahn School of Medicine at Mount Sinai,New York,NY,USA.
Kandler C Kandler Christian C Department of Psychology,MSB Medical School Berlin,School of Health and Medicine,Berlin,Germany.
Honda C Honda Chika C Osaka University Graduate School of Medicine,Osaka University,Osaka,Japan.
Inui F Inui Fujio F Osaka University Graduate School of Medicine,Osaka University,Osaka,Japan.
Iwatani Y Iwatani Yoshinori Y Osaka University Graduate School of Medicine,Osaka University,Osaka,Japan.
Watanabe M Watanabe Mikio M Osaka University Graduate School of Medicine,Osaka University,Osaka,Japan.
Rebato E Rebato Esther E Department of Genetics,Physical Anthropology and Animal Physiology,University of the Basque Country UPV/EHU,Leioa,Spain.
Stazi MA Stazi Maria A MA Istituto Superiore di Sanità - Centre for Behavioural Sciences and Mental Health,Rome,Italy.
Fagnani C Fagnani Corrado C Istituto Superiore di Sanità - Centre for Behavioural Sciences and Mental Health,Rome,Italy.
Brescianini S Brescianini Sonia S Istituto Superiore di Sanità - Centre for Behavioural Sciences and Mental Health,Rome,Italy.
Hur YM Hur Yoon-Mi YM Department of Education,Mokpo National University,Jeonnam,South Korea.
Jeong HU Jeong Hoe-Uk HU Department of Education,Mokpo National University,Jeonnam,South Korea.
Cutler TL Cutler Tessa L TL The Australian Twin Registry,Centre for Epidemiology and Biostatistics,The University of Melbourne,Melbourne,Australia.
Hopper JL Hopper John L JL The Australian Twin Registry,Centre for Epidemiology and Biostatistics,The University of Melbourne,Melbourne,Australia.
Busjahn A Busjahn Andreas A HealthTwiSt GmbH,Berlin,Germany.
Saudino KJ Saudino Kimberly J KJ Department of Psychological and Brain Sciencies,Boston University,Boston,MA,USA.
Ji F Ji Fuling F Department of Noncommunicable Diseases Prevention,Qingdao Centers for Disease Control and Prevention,Qingdao,China.
Ning F Ning Feng F Department of Noncommunicable Diseases Prevention,Qingdao Centers for Disease Control and Prevention,Qingdao,China.
Pang Z Pang Zengchang Z Department of Noncommunicable Diseases Prevention,Qingdao Centers for Disease Control and Prevention,Qingdao,China.
Rose RJ Rose Richard J RJ Department of Psychological and Brain Sciences,Indiana University,Bloomington,IN,USA.
Koskenvuo M Koskenvuo Markku M Institute for Molecular Medicine FIMM,Helsinki,Finland.
Heikkilä K Heikkilä Kauko K Institute for Molecular Medicine FIMM,Helsinki,Finland.
Cozen W Cozen Wendy W Department of Preventive Medicine,Keck School of Medicine of USC,University of Southern California,Los Angeles,CA,USA.
Hwang AE Hwang Amie E AE Department of Preventive Medicine,Keck School of Medicine of USC,University of Southern California,Los Angeles,CA,USA.
Mack TM Mack Thomas M TM Department of Preventive Medicine,Keck School of Medicine of USC,University of Southern California,Los Angeles,CA,USA.
Siribaddana SH Siribaddana Sisira H SH Institute of Research & Development,Battaramulla,Sri Lanka.
Hotopf M Hotopf Matthew M NIHR Mental Health Biomedical Research Centre,South London and Maudsley NHS Foundation Trust,and Institute of Psychiatry,Psychology and Neuroscience, King's College London,London,UK.
Sumathipala A Sumathipala Athula A Institute of Research & Development,Battaramulla,Sri Lanka.
Rijsdijk F Rijsdijk Fruhling F MRC Social,Genetic & Developmental Psychiatry Centre,Institute of Psychiatry, Psychology and Neuroscience, King's College London,London,UK.
Sung J Sung Joohon J Department of Epidemiology,School of Public Health,Seoul National University,Seoul,South Korea.
Kim J Kim Jina J Department of Epidemiology,School of Public Health,Seoul National University,Seoul,South Korea.
Lee J Lee Jooyeon J Department of Epidemiology,School of Public Health,Seoul National University,Seoul,South Korea.
Lee S Lee Sooji S Department of Epidemiology,School of Public Health,Seoul National University,Seoul,South Korea.
Nelson TL Nelson Tracy L TL Department of Health and Exercise Sciences and Colorado School of Public Health,Colorado State University,Fort Collins,CO,USA.
Whitfield KE Whitfield Keith E KE Psychology and Neuroscience,Duke University,Durham,NC,USA.
Tan Q Tan Qihua Q Department of Public Health,Epidemiology,Biostatistics and Biodemography,University of Southern Denmark,Odense,Denmark.
Zhang D Zhang Dongfeng D Department of Public Health,Qingdao University Medical College,Qingdao,China.
Llewellyn CH Llewellyn Clare H CH Health Behaviour Research Centre,Department of Epidemiology and Public Health,Institute of Epidemiology and Health Care, University College London,London,UK.
Fisher A Fisher Abigail A Health Behaviour Research Centre,Department of Epidemiology and Public Health,Institute of Epidemiology and Health Care, University College London,London,UK.
Burt SA Burt S Alexandra SA Michigan State University,East Lansing,MI,USA.
Klump KL Klump Kelly L KL Michigan State University,East Lansing,MI,USA.
Knafo-Noam A Knafo-Noam Ariel A The Hebrew University of Jerusalem,Jerusalem,Israel.
Mankuta D Mankuta David D Hadassah Hospital Obstetrics and Gynecology Department,Hebrew University Medical School,Jerusalem,Israel.
Abramson L Abramson Lior L The Hebrew University of Jerusalem,Jerusalem,Israel.
Medland SE Medland Sarah E SE Genetic Epidemiology Department,QIMR Berghofer Medical Research Institute,Brisbane,Australia.
Martin NG Martin Nicholas G NG Genetic Epidemiology Department,QIMR Berghofer Medical Research Institute,Brisbane,Australia.
Montgomery GW Montgomery Grant W GW Molecular Epidemiology Department,QIMR Berghofer Medical Research Institute,Brisbane,Australia.
Magnusson PKE Magnusson Patrik K E PKE Department of Medical Epidemiology and Biostatistics,Karolinska Institutet,Stockholm,Sweden.
Pedersen NL Pedersen Nancy L NL Department of Medical Epidemiology and Biostatistics,Karolinska Institutet,Stockholm,Sweden.
Dahl Aslan AK Dahl Aslan Anna K AK Department of Medical Epidemiology and Biostatistics,Karolinska Institutet,Stockholm,Sweden.
Corley RP Corley Robin P RP Institute for Behavioral Genetics,University of Colorado,Boulder,CO,USA.
Huibregtse BM Huibregtse Brooke M BM Institute for Behavioral Genetics,University of Colorado,Boulder,CO,USA.
Öncel SY Öncel Sevgi Y SY Department of Statistics,Faculty of Arts and Sciences,Kırıkkale University,Kırıkkale,Turkey.
Aliev F Aliev Fazil F Psychology and African American Studies,Virginia Commonwealth University,Richmond,VA,USA.
Krueger RF Krueger Robert F RF Department of Psychology,University of Minnesota,Minneapolis,MN,USA.
McGue M McGue Matt M Department of Psychology,University of Minnesota,Minneapolis,MN,USA.
Pahlen S Pahlen Shandell S Department of Psychology,University of Minnesota,Minneapolis,MN,USA.
Willemsen G Willemsen Gonneke G Department of Biological Psychology,VU University Amsterdam,Amsterdam,the Netherlands.
Bartels M Bartels Meike M Department of Biological Psychology,VU University Amsterdam,Amsterdam,the Netherlands.
van Beijsterveldt CEM van Beijsterveldt Catharina E M CEM Department of Biological Psychology,VU University Amsterdam,Amsterdam,the Netherlands.
Silberg JL Silberg Judy L JL Department of Human and Molecular Genetics,Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University,Richmond,VA,USA.
Eaves LJ Eaves Lindon J LJ Department of Human and Molecular Genetics,Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University,Richmond,VA,USA.
Maes HH Maes Hermine H HH Department of Human and Molecular Genetics,Psychiatry and Massey Cancer Center,Virginia Commonwealth University,Richmond,VA,USA.
Harris JR Harris Jennifer R JR Norwegian Institute of Public Health,Oslo,Norway.
Brandt I Brandt Ingunn I Norwegian Institute of Public Health,Oslo,Norway.
Nilsen TS Nilsen Thomas S TS Norwegian Institute of Public Health,Oslo,Norway.
Rasmussen F Rasmussen Finn F Lund University,Lund,Sweden.
Tynelius P Tynelius Per P Department of Public Health Sciences,Karolinska Institutet,Stockholm,Sweden.
Baker LA Baker Laura A LA Department of Psychology,University of Southern California,Los Angeles,CA,USA.
Tuvblad C Tuvblad Catherine C Department of Psychology,University of Southern California,Los Angeles,CA,USA.
Ordoñana JR Ordoñana Juan R JR Department of Human Anatomy and Psychobiology,University of Murcia,Murcia,Spain.
Sánchez-Romera JF Sánchez-Romera Juan F JF Department of Human Anatomy and Psychobiology,University of Murcia,Murcia,Spain.
Colodro-Conde L Colodro-Conde Lucia L Department of Human Anatomy and Psychobiology,University of Murcia,Murcia,Spain.
Gatz M Gatz Margaret M Department of Medical Epidemiology and Biostatistics,Karolinska Institutet,Stockholm,Sweden.
Butler DA Butler David A DA Health and Medicine Division,The National Academies of Sciences,Engineering, and Medicine,Washington,DC,USA.
Lichtenstein P Lichtenstein Paul P Department of Medical Epidemiology and Biostatistics,Karolinska Institutet,Stockholm,Sweden.
Goldberg JH Goldberg Jack H JH Department of Epidemiology,School of Public Health,University of Washington,Seattle,WA,USA.
Harden KP Harden K Paige KP Department of Psychology,University of Texas at Austin,Austin,TX,USA.
Tucker-Drob EM Tucker-Drob Elliot M EM Department of Psychology,University of Texas at Austin,Austin,TX,USA.
Duncan GE Duncan Glen E GE Washington State Twin Registry,Washington State University - Health Sciences Spokane,Spokane,WA,USA.
Buchwald D Buchwald Dedra D Washington State Twin Registry,Washington State University - Health Sciences Spokane,Spokane,WA,USA.
Tarnoki AD Tarnoki Adam D AD Department of Radiology,Semmelweis University,Budapest,Hungary.
Tarnoki DL Tarnoki David L DL Department of Radiology,Semmelweis University,Budapest,Hungary.
Franz CE Franz Carol E CE Department of Psychiatry,University of California,San Diego,CA,USA.
Kremen WS Kremen William S WS Department of Psychiatry,University of California,San Diego,CA,USA.
Lyons MJ Lyons Michael J MJ Department of Psychology,Boston University,Boston,MA,USA.
Maia JA Maia José A JA CIFI2D,Faculty of Sport,University of Porto,Porto,Portugal.
Freitas DL Freitas Duarte L DL Department of Physical Education and Sport,University of Madeira,Funchal,Portugal.
Turkheimer E Turkheimer Eric E Department of Psychology,University of Virginia,Charlottesville,VA,USA.
Sørensen TIA Sørensen Thorkild I A TIA Novo Nordisk Foundation Centre for Basic Metabolic Research (Section on Metabolic Genetics),and Department of Public Health,Faculty of Health and Medical Sciences,University of Copenhagen,Copenhagen,Denmark.
Boomsma DI Boomsma Dorret I DI Department of Biological Psychology,VU University Amsterdam,Amsterdam,the Netherlands.
Kaprio J Kaprio Jaakko J Institute for Molecular Medicine FIMM,Helsinki,Finland.
INVESTIGATORS
JOURNAL
VOLUME: 20
ISSUE: 5
TITLE: Twin research and human genetics : the official journal of the International Society for Twin Studies
ISOABBREVIATION: Twin Res Hum Genet
YEAR: 2017
MONTH: Oct
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Internet
ISSN: 1832-4274
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Twin Res Hum Genet
COUNTRY: England
ISSNLINKING: 1832-4274
NLMUNIQUEID: 101244624
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
KEYWORD
education
parental education
twins
zygosity
MESH HEADINGS
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's