Genetic Epidemiology, Psychiatric Genetics, Asthma Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
26693596
TITLE
The Genetic and Environmental Contributions to Internet Use and Associations With Psychopathology: A Twin Study.
ABSTRACT
Excessive internet use has been linked to psychopathology. Therefore, understanding the genetic and environmental risks underpinning internet use and their relation to psychopathology is important. This study aims to explore the genetic and environmental etiology of internet use measures and their associations with internalizing disorders and substance use disorders. The sample included 2,059 monozygotic (MZ) and dizygotic (DZ) young adult twins from the Brisbane Longitudinal Twin Study (BLTS). Younger participants reported more frequent internet use, while women were more likely to use the internet for interpersonal communication. Familial aggregation in 'frequency of internet use' was entirely explained by additive genetic factors accounting for 41% of the variance. Familial aggregation in 'frequency of use after 11 pm', 'using the internet to contact peers', and 'using the internet primarily to access social networking sites' was attributable to varying combinations of additive genetic and shared environmental factors. In terms of psychopathology, there were no significant associations between internet use measures and major depression (MD), but there were positive significant associations between 'frequency of internet use' and 'frequency of use after 11 pm' with social phobia (SP). 'Using the internet to contact peers' was positively associated with alcohol abuse, whereas 'using the internet to contact peers' and 'using the internet primarily to access social networking sites' were negatively associated with cannabis use disorders and nicotine symptoms. Individual differences in internet use can be attributable to varying degrees of genetic and environmental risks. Despite some significant associations of small effect, variation in internet use appears mostly unrelated to psychopathology.
DATE PUBLISHED
2016 Feb
HISTORY
PUBSTATUS PUBSTATUSDATE
entrez 2015/12/24 06:00
pubmed 2015/12/24 06:00
medline 2016/10/25 06:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Long EC Long Elizabeth C EC Department of Psychiatry,Virginia Institute for Psychiatric and Behavioral Genetics,Virginia Commonwealth University,Richmond,Virginia,USA.
Verhulst B Verhulst Brad B Department of Psychiatry,Virginia Institute for Psychiatric and Behavioral Genetics,Virginia Commonwealth University,Richmond,Virginia,USA.
Neale MC Neale Michael C MC Department of Psychiatry,Virginia Institute for Psychiatric and Behavioral Genetics,Virginia Commonwealth University,Richmond,Virginia,USA.
Lind PA Lind Penelope A PA QIMR Berghofer Medical Research Institute,Quantitative Genetics,Brisbane,Queensland,Australia.
Hickie IB Hickie Ian B IB Brain & Mind Research Institute,University of Sydney,Sydney,New South Wales,Australia.
Martin NG Martin Nicholas G NG QIMR Berghofer Medical Research Institute,Genetic Epidemiology,Brisbane,Queensland,Australia.
Gillespie NA Gillespie Nathan A NA Department of Psychiatry,Virginia Institute for Psychiatric and Behavioral Genetics,Virginia Commonwealth University,Richmond,Virginia,USA.
INVESTIGATORS
JOURNAL
VOLUME: 19
ISSUE: 1
TITLE: Twin research and human genetics : the official journal of the International Society for Twin Studies
ISOABBREVIATION: Twin Res Hum Genet
YEAR: 2016
MONTH: Feb
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Internet
ISSN: 1832-4274
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Twin Res Hum Genet
COUNTRY: England
ISSNLINKING: 1832-4274
NLMUNIQUEID: 101244624
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Twin Study
COMMENTS AND CORRECTIONS
REFTYPE REFSOURCE REFPMID NOTE
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GRANTS
GRANTID AGENCY COUNTRY
R25 DA026119 NIDA NIH HHS United States
R00DA023549 NIDA NIH HHS United States
K99 DA023549 NIDA NIH HHS United States
R01 MH065322 NIMH NIH HHS United States
R00 DA023549 NIDA NIH HHS United States
R01 DA018673 NIDA NIH HHS United States
GENERAL NOTE
KEYWORDS
KEYWORD
internalizing disorders
internet use
substance use disorders
twins
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adolescent
Adult
Alcoholism psychology
Behavior, Addictive psychology
Depressive Disorder, Major psychology
Female psychology
Gene-Environment Interaction psychology
Humans psychology
Internet psychology
Life Style psychology
Longitudinal Studies psychology
Male psychology
Mental Disorders psychology
Phobic Disorders psychology
Risk Factors psychology
Substance-Related Disorders psychology
Twins, Dizygotic genetics
Twins, Monozygotic genetics
Young Adult genetics
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's
OTHERID SOURCE
NIHMS758823 NLM
PMC4756632 NLM