Genetic Epidemiology, Psychiatric Genetics, Asthma Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
26014041
TITLE
The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits.
ABSTRACT
NlmCategory: UNASSIGNED
For over 100 years, the genetics of human anthropometric traits has attracted scientific interest. In particular, height and body mass index (BMI, calculated as kg/m2) have been under intensive genetic research. However, it is still largely unknown whether and how heritability estimates vary between human populations. Opportunities to address this question have increased recently because of the establishment of many new twin cohorts and the increasing accumulation of data in established twin cohorts. We started a new research project to analyze systematically (1) the variation of heritability estimates of height, BMI and their trajectories over the life course between birth cohorts, ethnicities and countries, and (2) to study the effects of birth-related factors, education and smoking on these anthropometric traits and whether these effects vary between twin cohorts. We identified 67 twin projects, including both monozygotic (MZ) and dizygotic (DZ) twins, using various sources. We asked for individual level data on height and weight including repeated measurements, birth related traits, background variables, education and smoking. By the end of 2014, 48 projects participated. Together, we have 893,458 height and weight measures (52% females) from 434,723 twin individuals, including 201,192 complete twin pairs (40% monozygotic, 40% same-sex dizygotic and 20% opposite-sex dizygotic) representing 22 countries. This project demonstrates that large-scale international twin studies are feasible and can promote the use of existing data for novel research purposes.
DATE PUBLISHED
2015 May 27
HISTORY
PUBSTATUS PUBSTATUSDATE
entrez 2015/05/28 06:00
pubmed 2015/05/28 06:00
medline 2015/05/28 06:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Silventoinen K Silventoinen Karri K Department of Social Research,University of Helsinki,Helsinki,Finland.
Jelenkovic A Jelenkovic Aline A Department of Social Research,University of Helsinki,Helsinki,Finland.
Sund R Sund Reijo R Department of Social Research,University of Helsinki,Helsinki,Finland.
Honda C Honda Chika C Osaka University Graduate School of Medicine,Osaka University,Osaka,Japan.
Aaltonen S Aaltonen Sari S Department of Social Research,University of Helsinki,Helsinki,Finland.
Yokoyama Y Yokoyama Yoshie Y Department of Public Health Nursing,Osaka City University,Osaka,Japan.
Tarnoki AD Tarnoki Adam D AD Department of Radiology and Oncotherapy,Semmelweis University,Budapest,Hungary.
Tarnoki DL Tarnoki David L DL Department of Radiology and Oncotherapy,Semmelweis University,Budapest,Hungary.
Ning F Ning Feng F Department of Noncommunicable Diseases Prevention,Qingdao Centers for Disease Control and Prevention,Qingdao,China.
Ji F Ji Fuling F Department of Noncommunicable Diseases Prevention,Qingdao Centers for Disease Control and Prevention,Qingdao,China.
Pang Z Pang Zengchang Z Department of Noncommunicable Diseases Prevention,Qingdao Centers for Disease Control and Prevention,Qingdao,China.
Ordoñana JR Ordoñana Juan R JR Department of Human Anatomy and Psychobiology,University of Murcia,Murcia,Spain.
Sánchez-Romera JF Sánchez-Romera Juan F JF IMIB-Arrixaca,Murcia,Spain.
Colodro-Conde L Colodro-Conde Lucia L Department of Human Anatomy and Psychobiology,University of Murcia,Murcia,Spain.
Burt SA Burt S Alexandra SA Michigan State University,East Lansing,MI,USA.
Klump KL Klump Kelly L KL Michigan State University,East Lansing,MI,USA.
Medland SE Medland Sarah E SE QIMR Berghofer Medical Research Institute,Brisbane,Queensland,Australia.
Montgomery GW Montgomery Grant W GW QIMR Berghofer Medical Research Institute,Brisbane,Queensland,Australia.
Kandler C Kandler Christian C Department of Psychology,Bielefeld University,Bielefeld,Germany.
McAdams TA McAdams Tom A TA MRC Social,Genetic & Developmental Psychiatry Centre,Institute of Psychiatry,Psychology & Neuroscience,King's College London,London,UK.
Eley TC Eley Thalia C TC MRC Social,Genetic & Developmental Psychiatry Centre,Institute of Psychiatry,Psychology & Neuroscience,King's College London,London,UK.
Gregory AM Gregory Alice M AM Department of Psychology,Goldsmiths,University of London,London,UK.
Saudino KJ Saudino Kimberly J KJ Department of Psychological and Brain Sciences,Boston University,Boston,MA,USA.
Dubois L Dubois Lise L School of Epidemiology,Public Health and Preventive Medicine,University of Ottawa,Ottawa,Ontario,Canada.
Boivin M Boivin Michel M École de psychologie,Université Laval,Québec,Canada.
Haworth CM Haworth Claire M A CM Department of Psychology,University of Warwick Coventry,Coventry,UK.
Plomin R Plomin Robert R MRC Social,Genetic & Developmental Psychiatry Centre,Institute of Psychiatry,Psychology & Neuroscience,King's College London,London,UK.
Öncel SY Öncel Sevgi Y SY Department of Statistics,Faculty of Arts and Sciences,Kırıkkale University,Kırıkkale,Turkey.
Aliev F Aliev Fazil F Departments of Psychiatry,Psychology,and Human and Molecular Genetics,Virginia Institute for Psychiatric and Behavioral Genetics,Virginia Commonwealth University,Richmond,VA,USA.
Stazi MA Stazi Maria A MA Istituto Superiore di Sanità -- National Center for Epidemiology,Surveillance and Health Promotion,Rome,Italy.
Fagnani C Fagnani Corrado C Istituto Superiore di Sanità -- National Center for Epidemiology,Surveillance and Health Promotion,Rome,Italy.
D'Ippolito C D'Ippolito Cristina C Istituto Superiore di Sanità -- National Center for Epidemiology,Surveillance and Health Promotion,Rome,Italy.
Craig JM Craig Jeffrey M JM Murdoch Childrens Research Institute,Royal Children's Hospital,Melbourne,Victoria,Australia.
Saffery R Saffery Richard R Murdoch Childrens Research Institute,Royal Children's Hospital,Melbourne,Victoria,Australia.
Siribaddana SH Siribaddana Sisira H SH Institute of Research & Development,Battaramulla,Sri Lanka.
Hotopf M Hotopf Matthew M NIHR Mental Health Biomedical Research Centre,South London and Maudsley NHS Foundation Trust and,Institute of Psychiatry Psychology and Neuroscience,King's College London,London,UK.
Sumathipala A Sumathipala Athula A Institute of Research & Development,Battaramulla,Sri Lanka.
Spector T Spector Timothy T Department of Twin Research and Genetic epidemiology,King's College,London,UK.
Mangino M Mangino Massimo M Department of Twin Research and Genetic epidemiology,King's College,London,UK.
Lachance G Lachance Genevieve G Department of Twin Research and Genetic epidemiology,King's College,London,UK.
Gatz M Gatz Margaret M Department of Psychology,University of Southern California,Los Angeles,CA,USA.
Butler DA Butler David A DA Institute of Medicine,National Academy of Sciences,Washington,DC,USA.
Bayasgalan G Bayasgalan Gombojav G Healthy Twin Association of Mongolia,Ulaanbaatar,Mongolia.
Narandalai D Narandalai Danshiitsoodol D Healthy Twin Association of Mongolia,Ulaanbaatar,Mongolia.
Freitas DL Freitas Duarte L DL Department of Physical Education and Sport,University of Madeira,Funchal,Portugal.
Maia JA Maia José Antonio JA CIFI2D,Faculty of Sport,University of Porto,Porto,Portugal.
Harden KP Harden K Paige KP Department of Psychology,University of Texas at Austin,Austin,TX,USA.
Tucker-Drob EM Tucker-Drob Elliot M EM Department of Psychology,University of Texas at Austin,Austin,TX,USA.
Christensen K Christensen Kaare K The Danish Twin Registry,Institute of Public Health,Epidemiology,Biostatistics & Biodemography,University of Southern Denmark,Odense,Denmark.
Skytthe A Skytthe Axel A The Danish Twin Registry,Institute of Public Health,Epidemiology,Biostatistics & Biodemography,University of Southern Denmark,Odense,Denmark.
Kyvik KO Kyvik Kirsten O KO Department of Clinical Research,University of Southern Denmark,Odense,Denmark.
Hong C Hong Changhee C Department of Psychology,Pusan National University,Busan,South Korea.
Chong Y Chong Youngsook Y Department of Psychology,Pusan National University,Busan,South Korea.
Derom CA Derom Catherine A CA Centre of Human Genetics,University Hospitals Leuven,Leuven,Belgium.
Vlietinck RF Vlietinck Robert F RF Centre of Human Genetics,University Hospitals Leuven,Leuven,Belgium.
Loos RJ Loos Ruth J F RJ The Charles Bronfman Institute for Personalized Medicine,The Mindich Child Health and Development Institute,Icahn School of Medicine at Mount Sinai,New York,NY,USA.
Cozen W Cozen Wendy W Department of Preventive Medicine,Keck School of Medicine of USC,University of Southern California,Los Angeles,CA,USA.
Hwang AE Hwang Amie E AE Department of Preventive Medicine,Keck School of Medicine of USC,University of Southern California,Los Angeles,CA,USA.
Mack TM Mack Thomas M TM Department of Preventive Medicine,Keck School of Medicine of USC,University of Southern California,Los Angeles,CA,USA.
He M He Mingguang M State Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangzhou,China.
Ding X Ding Xiaohu X State Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangzhou,China.
Chang B Chang Billy B State Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangzhou,China.
Silberg JL Silberg Judy L JL Department of Human and Molecular Genetics,Virginia Institute for Psychiatric and Behavioral Genetics,Virginia Commonwealth University,Richmond,VA,USA.
Eaves LJ Eaves Lindon J LJ Department of Human and Molecular Genetics,Virginia Institute for Psychiatric and Behavioral Genetics,Virginia Commonwealth University,Richmond,VA,USA.
Maes HH Maes Hermine H HH Department of Human and Molecular Genetics,Psychiatry & Massey Cancer Center,Virginia Commonwealth University,Richmond,VA,USA.
Cutler TL Cutler Tessa L TL The Australian Twin Registry,Centre for Epidemiology and Biostatistics,The University of Melbourne,Melbourne,Victoria,Australia.
Hopper JL Hopper John L JL The Australian Twin Registry,Centre for Epidemiology and Biostatistics,The University of Melbourne,Melbourne,Victoria,Australia.
Aujard K Aujard Kelly K Centre for Epidemiology and Biostatistics,The University of Melbourne,Melbourne,Victoria,Australia.
Magnusson PK Magnusson Patrik K E PK Department of Medical Epidemiology and Biostatistics,Karolinska Institutet,Stockholm,Sweden.
Pedersen NL Pedersen Nancy L NL Department of Medical Epidemiology and Biostatistics,Karolinska Institutet,Stockholm,Sweden.
Aslan AK Aslan Anna K Dahl AK Department of Medical Epidemiology and Biostatistics,Karolinska Institutet,Stockholm,Sweden.
Song YM Song Yun-Mi YM Department of Family Medicine,Samsung Medical Center,Sungkyunkwan University School of Medicine,Seoul,South Korea.
Yang S Yang Sarah S Department of Epidemiology,School of Public Health,Seoul National University,Seoul,South Korea.
Lee K Lee Kayoung K Department of Family Medicine,Busan Paik Hospital,Inje University College of Medicine,Busan,South Korea.
Baker LA Baker Laura A LA Department of Psychology,University of Southern California,Los Angeles,CA,USA.
Tuvblad C Tuvblad Catherine C Department of Psychology,University of Southern California,Los Angeles,CA,USA.
Bjerregaard-Andersen M Bjerregaard-Andersen Morten M Bandim Health Project,INDEPTH Network,Apartado,Bissau Codex,Guinea-Bissau.
Beck-Nielsen H Beck-Nielsen Henning H Department of Endocrinology,Odense University Hospital,Odense,Denmark.
Sodemann M Sodemann Morten M Department of Infectious Diseases,Odense University Hospital,Odense,Denmark.
Heikkilä K Heikkilä Kauko K Department of Public Health,University of Helsinki,Helsinki,Finland.
Tan Q Tan Qihua Q Epidemiology,Biostatistics and Biodemography,Institute of Public Health,University of Southern Denmark,Odense,Denmark.
Zhang D Zhang Dongfeng D Department of Public Health,Qingdao University Medical College,Qingdao,China.
Swan GE Swan Gary E GE Stanford Prevention Research Center,Department of Medicine,Stanford University School of Medicine,Stanford,CA,USA.
Krasnow R Krasnow Ruth R Center for Health Sciences,SRI International,Menlo Park,CA,USA.
Jang KL Jang Kerry L KL Department of Psychiatry,University of British Columbia,Vancouver,British Columbia,Canada.
Knafo-Noam A Knafo-Noam Ariel A The Hebrew University of Jerusalem,Jerusalem,Israel.
Mankuta D Mankuta David D Hadassah Hospital Obstetrics and Gynecology Department,Hebrew University Medical School,Jerusalem,Israel.
Abramson L Abramson Lior L The Hebrew University of Jerusalem,Jerusalem,Israel.
Lichtenstein P Lichtenstein Paul P Department of Medical Epidemiology and Biostatistics,Karolinska Institutet,Stockholm,Sweden.
Krueger RF Krueger Robert F RF Department of Psychology,University of Minnesota,Minneapolis,MN,USA.
McGue M McGue Matt M Department of Psychology,University of Minnesota,Minneapolis,MN,USA.
Pahlen S Pahlen Shandell S Department of Psychology,University of Minnesota,Minneapolis,MN,USA.
Tynelius P Tynelius Per P Department of Public Health Sciences,Karolinska Institutet,Stockholm,Sweden.
Duncan GE Duncan Glen E GE Center for Clinical and Epidemiological Research,University of Washington,Seattle,WA,USA.
Buchwald D Buchwald Dedra D Center for Clinical and Epidemiological Research,University of Washington,Seattle,WA,USA.
Corley RP Corley Robin P RP Institute for Behavioral Genetics,Boulder,CO,USA.
Huibregtse BM Huibregtse Brooke M BM Institute for Behavioral Genetics,Boulder,CO,USA.
Nelson TL Nelson Tracy L TL Department of Health and Exercise Sciences and Colorado School of Public Health,Colorado State University,Fort Collins,CO,USA.
Whitfield KE Whitfield Keith E KE Psychology and Neuroscience,Duke University,Durham,NC,USA.
Franz CE Franz Carol E CE Department of Psychiatry,University of California,San Diego,CA,USA.
Kremen WS Kremen William S WS Department of Psychiatry,University of California,San Diego,CA,USA.
Lyons MJ Lyons Michael J MJ Boston University,Department of Psychology,Boston,MA,USA.
Ooki S Ooki Syuichi S Department of Health Science,Ishikawa Prefectural Nursing University,Kahoku,Ishikawa,Japan.
Brandt I Brandt Ingunn I Norwegian Institute of Public Health,Division of Epidemiology,Department of Genes and Environment,Oslo,Norway.
Nilsen TS Nilsen Thomas Sevenius TS Norwegian Institute of Public Health,Division of Epidemiology,Department of Genes and Environment,Oslo,Norway.
Inui F Inui Fujio F Osaka University Graduate School of Medicine,Osaka University,Osaka,Japan.
Watanabe M Watanabe Mikio M Osaka University Graduate School of Medicine,Osaka University,Osaka,Japan.
Bartels M Bartels Meike M Department of Biological Psychology,VU University Amsterdam,Amsterdam,Netherlands.
van Beijsterveldt TC van Beijsterveldt Toos C E M TC Department of Biological Psychology,VU University Amsterdam,Amsterdam,Netherlands.
Wardle J Wardle Jane J Health Behaviour Research Centre,Department of Epidemiology and Public Health,Institute of Epidemiology and Health Care,University College London,London,UK.
Llewellyn CH Llewellyn Clare H CH Health Behaviour Research Centre,Department of Epidemiology and Public Health,Institute of Epidemiology and Health Care,University College London,London,UK.
Fisher A Fisher Abigail A Health Behaviour Research Centre,Department of Epidemiology and Public Health,Institute of Epidemiology and Health Care,University College London,London,UK.
Rebato E Rebato Esther E Department of Genetics,Physical Anthropology and Animal Physiology,University of the Basque Country UPV/EHU,Leioa,Spain.
Martin NG Martin Nicholas G NG QIMR Berghofer Medical Research Institute,Brisbane,Queensland,Australia.
Iwatani Y Iwatani Yoshinori Y Osaka University Graduate School of Medicine,Osaka University,Osaka,Japan.
Hayakawa K Hayakawa Kazuo K Osaka University Graduate School of Medicine,Osaka University,Osaka,Japan.
Rasmussen F Rasmussen Finn F Department of Public Health Sciences,Karolinska Institutet,Stockholm,Sweden.
Sung J Sung Joohon J Department of Epidemiology,School of Public Health,Seoul National University,Seoul,South Korea.
Harris JR Harris Jennifer R JR Norwegian Institute of Public Health,Division of Epidemiology,Department of Genes and Environment,Oslo,Norway.
Willemsen G Willemsen Gonneke G Department of Biological Psychology,VU University Amsterdam,Amsterdam,Netherlands.
Busjahn A Busjahn Andreas A HealthTwiSt GmbH,Berlin,Germany.
Goldberg JH Goldberg Jack H JH Department of Epidemiology,School of Public Health,University of Washington,Seattle,WA,USA.
Boomsma DI Boomsma Dorret I DI Department of Biological Psychology,VU University Amsterdam,Amsterdam,Netherlands.
Hur YM Hur Yoon-Mi YM Department of Education,Mokpo National University,Jeonnam,South Korea.
Sørensen TI Sørensen Thorkild I A TI Novo Nordisk Foundation Centre for Basic Metabolic Research,Section on Metabolic Genetics,Faculty of Health and Medical Sciences,University of Copenhagen,Copenhagen,Denmark.
Kaprio J Kaprio Jaakko J Department of Public Health,University of Helsinki,Helsinki,Finland.
INVESTIGATORS
JOURNAL
VOLUME:
ISSUE:
TITLE: Twin research and human genetics : the official journal of the International Society for Twin Studies
ISOABBREVIATION: Twin Res Hum Genet
YEAR: 2015
MONTH: May
DAY: 27
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 1832-4274
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Twin Res Hum Genet
COUNTRY: England
ISSNLINKING: 1832-4274
NLMUNIQUEID: 101244624
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
JOURNAL ARTICLE
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
KEYWORD
BMI
height
heritability
international comparisons
twins
MESH HEADINGS
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's