|
|
| PMID |
|
|
| TITLE |
|
| The "Alzheimer's type" profile of semantic clustering in amnestic mild cognitive impairment. |
|
| ABSTRACT |
|
|
|
| Impairments in learning and recall have been well established in amnestic mild cognitive impairment (aMCI). However, a relative dearth of studies has examined the profiles of memory strategy use in persons with aMCI relative to those with Alzheimer's disease (AD). Participants with aMCI, nonamnestic MCI, AD, and healthy older adults were administered the California Verbal Learning Test-II (CVLT-II). Measures of semantic clustering and recall were obtained across learning and delayed recall trials. In addition, we investigated whether deficits in semantic clustering were related to progression from healthy aging to aMCI and from aMCI to AD. The aMCI group displayed similar semantic clustering performance as the AD participants, whereas the AD group showed greater impairments on recall relative to the aMCI participants. Control participants who progressed to aMCI showed reduced semantic clustering at the short delay at baseline compared to individuals who remained diagnostically stable across follow-up visits. These findings show that the ability to engage in an effective memory strategy is compromised in aMCI, before AD has developed, suggesting that disruptions in semantic networks are an early marker of the disease. (JINS, 2014, 20, 1-11). |
|
| DATE PUBLISHED |
|
|
| HISTORY |
|
| PUBSTATUS |
PUBSTATUSDATE |
| aheadofprint |
2014/02/13 |
| entrez |
2014/02/14 06:00 |
| pubmed |
2014/02/14 06:00 |
| medline |
2014/02/14 06:00 |
|
| AUTHORS |
|
| NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
| McLaughlin PM |
|
McLaughlin |
Paula M |
PM |
|
1 Department of Neurology, University of California, Los Angeles, Los Angeles, California. |
| Wright MJ |
|
Wright |
Matthew J |
MJ |
|
2 Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, California. |
| Larocca M |
|
Larocca |
Michael |
M |
|
4 Department of Psychology, University of Alabama, Birmingham, Alabama. |
| Nguyen PT |
|
Nguyen |
Peter T |
PT |
|
5 Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida. |
| Teng E |
|
Teng |
Edmond |
E |
|
1 Department of Neurology, University of California, Los Angeles, Los Angeles, California. |
| Apostolova LG |
|
Apostolova |
Liana G |
LG |
|
1 Department of Neurology, University of California, Los Angeles, Los Angeles, California. |
| Ringman JM |
|
Ringman |
John M |
JM |
|
1 Department of Neurology, University of California, Los Angeles, Los Angeles, California. |
| Zhou Y |
|
Zhou |
Yan |
Y |
|
1 Department of Neurology, University of California, Los Angeles, Los Angeles, California. |
| Cummings JL |
|
Cummings |
Jeffrey L |
JL |
|
7 Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, Nevada. |
| Woo E |
|
Woo |
Ellen |
E |
|
1 Department of Neurology, University of California, Los Angeles, Los Angeles, California. |
|
| INVESTIGATORS |
|
|
| JOURNAL |
|
| VOLUME: 20 |
| ISSUE: 4 |
| TITLE: Journal of the International Neuropsychological Society : JINS |
| ISOABBREVIATION: J Int Neuropsychol Soc |
| YEAR: 2014 |
| MONTH: Apr |
| DAY: |
| MEDLINEDATE: |
| SEASON: |
| CITEDMEDIUM: Internet |
| ISSN: 1469-7661 |
| ISSNTYPE: Electronic |
|
| MEDLINE JOURNAL |
|
| MEDLINETA: J Int Neuropsychol Soc |
| COUNTRY: England |
| ISSNLINKING: 1355-6177 |
| NLMUNIQUEID: 9503760 |
|
| PUBLICATION TYPE |
|
| PUBLICATIONTYPE TEXT |
| Journal Article |
| Research Support, N.I.H., Extramural |
| Research Support, Non-U.S. Gov't |
|
| COMMENTS AND CORRECTIONS |
|
| REFTYPE |
REFSOURCE |
REFPMID |
NOTE |
| Cites |
Clin Neuropsychol. 2000 Aug;14(3):295-302 |
11262704 |
|
| Cites |
Am J Psychiatry. 2012 Dec;169(12):1226-9 |
23212051 |
|
| Cites |
Am Psychol. 2001 Nov;56(11):851-64 |
11785152 |
|
| Cites |
J Int Neuropsychol Soc. 2002 Mar;8(3):425-35 |
11939700 |
|
| Cites |
Brain. 2003 Jun;126(Pt 6):1493-503 |
12764068 |
|
| Cites |
J Cogn Neurosci. 2003 Aug 15;15(6):821-32 |
14511535 |
|
| Cites |
Arch Clin Neuropsychol. 2004 Mar;19(2):203-14 |
15010086 |
|
| Cites |
J Intern Med. 2004 Sep;256(3):183-94 |
15324362 |
|
| Cites |
J Psychiatr Res. 1975 Nov;12(3):189-98 |
1202204 |
|
| Cites |
Neurology. 1984 Jul;34(7):939-44 |
6610841 |
|
| Cites |
Brain Lang. 1986 Jul;28(2):235-49 |
3730816 |
|
| Cites |
Brain. 1990 Apr;113 ( Pt 2):397-417 |
2328410 |
|
| Cites |
Acta Neuropathol. 1991;82(4):239-59 |
1759558 |
|
| Cites |
Neuropsychologia. 1992 Apr;30(4):301-14 |
1603295 |
|
| Cites |
J Neurol Neurosurg Psychiatry. 1994 Nov;57(11):1389-94 |
7964817 |
|
| Cites |
Brain. 1999 Mar;122 ( Pt 3):383-404 |
10094249 |
|
| Cites |
Neurology. 1999 Apr 22;52(7):1397-403 |
10227624 |
|
| Cites |
J Clin Exp Neuropsychol. 2005 Nov;27(8):1033-55 |
16273685 |
|
| Cites |
Cogn Behav Neurol. 2006 Jun;19(2):79-84 |
16783130 |
|
| Cites |
Cortex. 2006 Jul;42(5):675-84 |
16909626 |
|
| Cites |
J Int Neuropsychol Soc. 2006 Jul;12(4):570-4 |
16981610 |
|
| Cites |
Appl Neuropsychol. 2006;13(4):213-22 |
17362141 |
|
| Cites |
J Clin Exp Neuropsychol. 2007 Feb;29(2):187-97 |
17365254 |
|
| Cites |
Behav Neurol. 2008;19(1-2):35-40 |
18413914 |
|
| Cites |
Psychol Aging. 2008 Jun;23(2):353-65 |
18573009 |
|
| Cites |
J Int Neuropsychol Soc. 2010 Mar;16(2):342-51 |
20175939 |
|
| Cites |
Neuropsychologia. 2010 Mar;48(4):978-88 |
19954747 |
|
| Cites |
Neuroimage. 2010 May 15;51(1):488-99 |
20083211 |
|
| Cites |
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2011 May;18(3):280-92 |
21347885 |
|
| Cites |
J Clin Exp Neuropsychol. 2011 Jul;33(6):631-8 |
21644138 |
|
| Cites |
J Int Neuropsychol Soc. 2001 Jul;7(5):631-9 |
11459114 |
|
|
| GRANTS |
|
| GRANTID |
AGENCY |
COUNTRY |
| P50 AG016570 |
NIA NIH HHS |
United States |
| P50AG016570 |
NIA NIH HHS |
United States |
| R01 AG040770 |
NIA NIH HHS |
United States |
|
| GENERAL NOTE |
|
|
| KEYWORDS |
|
|
| MESH HEADINGS |
|
|
| SUPPLEMENTARY MESH |
|
|
| GENE SYMBOLS |
|
|
| CHEMICALS |
|
|
| OTHER ID's |
|
| OTHERID |
SOURCE |
| NIHMS591417 |
NLM |
| PMC4086918 |
NLM |
|
|
