|
PMID |
|
|
TITLE |
|
Common variants associated with plasma triglycerides and risk for coronary artery disease. |
|
ABSTRACT |
|
|
|
Triglycerides are transported in plasma by specific triglyceride-rich lipoproteins; in epidemiological studies, increased triglyceride levels correlate with higher risk for coronary artery disease (CAD). However, it is unclear whether this association reflects causal processes. We used 185 common variants recently mapped for plasma lipids (P < 5 × 10(-8) for each) to examine the role of triglycerides in risk for CAD. First, we highlight loci associated with both low-density lipoprotein cholesterol (LDL-C) and triglyceride levels, and we show that the direction and magnitude of the associations with both traits are factors in determining CAD risk. Second, we consider loci with only a strong association with triglycerides and show that these loci are also associated with CAD. Finally, in a model accounting for effects on LDL-C and/or high-density lipoprotein cholesterol (HDL-C) levels, the strength of a polymorphism's effect on triglyceride levels is correlated with the magnitude of its effect on CAD risk. These results suggest that triglyceride-rich lipoproteins causally influence risk for CAD. |
|
DATE PUBLISHED |
|
|
HISTORY |
|
PUBSTATUS |
PUBSTATUSDATE |
received |
2013/02/20 |
accepted |
2013/09/13 |
aheadofprint |
2013/10/06 |
entrez |
2013/10/08 06:00 |
pubmed |
2013/10/08 06:00 |
medline |
2014/01/09 06:00 |
|
AUTHORS |
|
NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
Do R |
|
Do |
Ron |
R |
|
1] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [3] Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA. [4] Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA. |
Willer CJ |
|
Willer |
Cristen J |
CJ |
|
|
Schmidt EM |
|
Schmidt |
Ellen M |
EM |
|
|
Sengupta S |
|
Sengupta |
Sebanti |
S |
|
|
Gao C |
|
Gao |
Chi |
C |
|
|
Peloso GM |
|
Peloso |
Gina M |
GM |
|
|
Gustafsson S |
|
Gustafsson |
Stefan |
S |
|
|
Kanoni S |
|
Kanoni |
Stavroula |
S |
|
|
Ganna A |
|
Ganna |
Andrea |
A |
|
|
Chen J |
|
Chen |
Jin |
J |
|
|
Buchkovich ML |
|
Buchkovich |
Martin L |
ML |
|
|
Mora S |
|
Mora |
Samia |
S |
|
|
Beckmann JS |
|
Beckmann |
Jacques S |
JS |
|
|
Bragg-Gresham JL |
|
Bragg-Gresham |
Jennifer L |
JL |
|
|
Chang HY |
|
Chang |
Hsing-Yi |
HY |
|
|
Demirkan A |
|
Demirkan |
Ayşe |
A |
|
|
Den Hertog HM |
|
Den Hertog |
Heleen M |
HM |
|
|
Donnelly LA |
|
Donnelly |
Louise A |
LA |
|
|
Ehret GB |
|
Ehret |
Georg B |
GB |
|
|
Esko T |
|
Esko |
Tõnu |
T |
|
|
Feitosa MF |
|
Feitosa |
Mary F |
MF |
|
|
Ferreira T |
|
Ferreira |
Teresa |
T |
|
|
Fischer K |
|
Fischer |
Krista |
K |
|
|
Fontanillas P |
|
Fontanillas |
Pierre |
P |
|
|
Fraser RM |
|
Fraser |
Ross M |
RM |
|
|
Freitag DF |
|
Freitag |
Daniel F |
DF |
|
|
Gurdasani D |
|
Gurdasani |
Deepti |
D |
|
|
Heikkilä K |
|
Heikkilä |
Kauko |
K |
|
|
Hyppönen E |
|
Hyppönen |
Elina |
E |
|
|
Isaacs A |
|
Isaacs |
Aaron |
A |
|
|
Jackson AU |
|
Jackson |
Anne U |
AU |
|
|
Johansson A |
|
Johansson |
Asa |
A |
|
|
Johnson T |
|
Johnson |
Toby |
T |
|
|
Kaakinen M |
|
Kaakinen |
Marika |
M |
|
|
Kettunen J |
|
Kettunen |
Johannes |
J |
|
|
Kleber ME |
|
Kleber |
Marcus E |
ME |
|
|
Li X |
|
Li |
Xiaohui |
X |
|
|
Luan J |
|
Luan |
Jian'an |
J |
|
|
Lyytikäinen LP |
|
Lyytikäinen |
Leo-Pekka |
LP |
|
|
Magnusson PK |
|
Magnusson |
Patrik K E |
PK |
|
|
Mangino M |
|
Mangino |
Massimo |
M |
|
|
Mihailov E |
|
Mihailov |
Evelin |
E |
|
|
Montasser ME |
|
Montasser |
May E |
ME |
|
|
Müller-Nurasyid M |
|
Müller-Nurasyid |
Martina |
M |
|
|
Nolte IM |
|
Nolte |
Ilja M |
IM |
|
|
O'Connell JR |
|
O'Connell |
Jeffrey R |
JR |
|
|
Palmer CD |
|
Palmer |
Cameron D |
CD |
|
|
Perola M |
|
Perola |
Markus |
M |
|
|
Petersen AK |
|
Petersen |
Ann-Kristin |
AK |
|
|
Sanna S |
|
Sanna |
Serena |
S |
|
|
Saxena R |
|
Saxena |
Richa |
R |
|
|
Service SK |
|
Service |
Susan K |
SK |
|
|
Shah S |
|
Shah |
Sonia |
S |
|
|
Shungin D |
|
Shungin |
Dmitry |
D |
|
|
Sidore C |
|
Sidore |
Carlo |
C |
|
|
Song C |
|
Song |
Ci |
C |
|
|
Strawbridge RJ |
|
Strawbridge |
Rona J |
RJ |
|
|
Surakka I |
|
Surakka |
Ida |
I |
|
|
Tanaka T |
|
Tanaka |
Toshiko |
T |
|
|
Teslovich TM |
|
Teslovich |
Tanya M |
TM |
|
|
Thorleifsson G |
|
Thorleifsson |
Gudmar |
G |
|
|
Van den Herik EG |
|
Van den Herik |
Evita G |
EG |
|
|
Voight BF |
|
Voight |
Benjamin F |
BF |
|
|
Volcik KA |
|
Volcik |
Kelly A |
KA |
|
|
Waite LL |
|
Waite |
Lindsay L |
LL |
|
|
Wong A |
|
Wong |
Andrew |
A |
|
|
Wu Y |
|
Wu |
Ying |
Y |
|
|
Zhang W |
|
Zhang |
Weihua |
W |
|
|
Absher D |
|
Absher |
Devin |
D |
|
|
Asiki G |
|
Asiki |
Gershim |
G |
|
|
Barroso I |
|
Barroso |
Inês |
I |
|
|
Been LF |
|
Been |
Latonya F |
LF |
|
|
Bolton JL |
|
Bolton |
Jennifer L |
JL |
|
|
Bonnycastle LL |
|
Bonnycastle |
Lori L |
LL |
|
|
Brambilla P |
|
Brambilla |
Paolo |
P |
|
|
Burnett MS |
|
Burnett |
Mary S |
MS |
|
|
Cesana G |
|
Cesana |
Giancarlo |
G |
|
|
Dimitriou M |
|
Dimitriou |
Maria |
M |
|
|
Doney AS |
|
Doney |
Alex S F |
AS |
|
|
Döring A |
|
Döring |
Angela |
A |
|
|
Elliott P |
|
Elliott |
Paul |
P |
|
|
Epstein SE |
|
Epstein |
Stephen E |
SE |
|
|
Eyjolfsson GI |
|
Eyjolfsson |
Gudmundur Ingi |
GI |
|
|
Gigante B |
|
Gigante |
Bruna |
B |
|
|
Goodarzi MO |
|
Goodarzi |
Mark O |
MO |
|
|
Grallert H |
|
Grallert |
Harald |
H |
|
|
Gravito ML |
|
Gravito |
Martha L |
ML |
|
|
Groves CJ |
|
Groves |
Christopher J |
CJ |
|
|
Hallmans G |
|
Hallmans |
Göran |
G |
|
|
Hartikainen AL |
|
Hartikainen |
Anna-Liisa |
AL |
|
|
Hayward C |
|
Hayward |
Caroline |
C |
|
|
Hernandez D |
|
Hernandez |
Dena |
D |
|
|
Hicks AA |
|
Hicks |
Andrew A |
AA |
|
|
Holm H |
|
Holm |
Hilma |
H |
|
|
Hung YJ |
|
Hung |
Yi-Jen |
YJ |
|
|
Illig T |
|
Illig |
Thomas |
T |
|
|
Jones MR |
|
Jones |
Michelle R |
MR |
|
|
Kaleebu P |
|
Kaleebu |
Pontiano |
P |
|
|
Kastelein JJ |
|
Kastelein |
John J P |
JJ |
|
|
Khaw KT |
|
Khaw |
Kay-Tee |
KT |
|
|
Kim E |
|
Kim |
Eric |
E |
|
|
Klopp N |
|
Klopp |
Norman |
N |
|
|
Komulainen P |
|
Komulainen |
Pirjo |
P |
|
|
Kumari M |
|
Kumari |
Meena |
M |
|
|
Langenberg C |
|
Langenberg |
Claudia |
C |
|
|
Lehtimäki T |
|
Lehtimäki |
Terho |
T |
|
|
Lin SY |
|
Lin |
Shih-Yi |
SY |
|
|
Lindström J |
|
Lindström |
Jaana |
J |
|
|
Loos RJ |
|
Loos |
Ruth J F |
RJ |
|
|
Mach F |
|
Mach |
François |
F |
|
|
McArdle WL |
|
McArdle |
Wendy L |
WL |
|
|
Meisinger C |
|
Meisinger |
Christa |
C |
|
|
Mitchell BD |
|
Mitchell |
Braxton D |
BD |
|
|
Müller G |
|
Müller |
Gabrielle |
G |
|
|
Nagaraja R |
|
Nagaraja |
Ramaiah |
R |
|
|
Narisu N |
|
Narisu |
Narisu |
N |
|
|
Nieminen TV |
|
Nieminen |
Tuomo V M |
TV |
|
|
Nsubuga RN |
|
Nsubuga |
Rebecca N |
RN |
|
|
Olafsson I |
|
Olafsson |
Isleifur |
I |
|
|
Ong KK |
|
Ong |
Ken K |
KK |
|
|
Palotie A |
|
Palotie |
Aarno |
A |
|
|
Papamarkou T |
|
Papamarkou |
Theodore |
T |
|
|
Pomilla C |
|
Pomilla |
Cristina |
C |
|
|
Pouta A |
|
Pouta |
Anneli |
A |
|
|
Rader DJ |
|
Rader |
Daniel J |
DJ |
|
|
Reilly MP |
|
Reilly |
Muredach P |
MP |
|
|
Ridker PM |
|
Ridker |
Paul M |
PM |
|
|
Rivadeneira F |
|
Rivadeneira |
Fernando |
F |
|
|
Rudan I |
|
Rudan |
Igor |
I |
|
|
Ruokonen A |
|
Ruokonen |
Aimo |
A |
|
|
Samani N |
|
Samani |
Nilesh |
N |
|
|
Scharnagl H |
|
Scharnagl |
Hubert |
H |
|
|
Seeley J |
|
Seeley |
Janet |
J |
|
|
Silander K |
|
Silander |
Kaisa |
K |
|
|
Stančáková A |
|
Stančáková |
Alena |
A |
|
|
Stirrups K |
|
Stirrups |
Kathleen |
K |
|
|
Swift AJ |
|
Swift |
Amy J |
AJ |
|
|
Tiret L |
|
Tiret |
Laurence |
L |
|
|
Uitterlinden AG |
|
Uitterlinden |
Andre G |
AG |
|
|
van Pelt LJ |
|
van Pelt |
L Joost |
LJ |
|
|
Vedantam S |
|
Vedantam |
Sailaja |
S |
|
|
Wainwright N |
|
Wainwright |
Nicholas |
N |
|
|
Wijmenga C |
|
Wijmenga |
Cisca |
C |
|
|
Wild SH |
|
Wild |
Sarah H |
SH |
|
|
Willemsen G |
|
Willemsen |
Gonneke |
G |
|
|
Wilsgaard T |
|
Wilsgaard |
Tom |
T |
|
|
Wilson JF |
|
Wilson |
James F |
JF |
|
|
Young EH |
|
Young |
Elizabeth H |
EH |
|
|
Zhao JH |
|
Zhao |
Jing Hua |
JH |
|
|
Adair LS |
|
Adair |
Linda S |
LS |
|
|
Arveiler D |
|
Arveiler |
Dominique |
D |
|
|
Assimes TL |
|
Assimes |
Themistocles L |
TL |
|
|
Bandinelli S |
|
Bandinelli |
Stefania |
S |
|
|
Bennett F |
|
Bennett |
Franklyn |
F |
|
|
Bochud M |
|
Bochud |
Murielle |
M |
|
|
Boehm BO |
|
Boehm |
Bernhard O |
BO |
|
|
Boomsma DI |
|
Boomsma |
Dorret I |
DI |
|
|
Borecki IB |
|
Borecki |
Ingrid B |
IB |
|
|
Bornstein SR |
|
Bornstein |
Stefan R |
SR |
|
|
Bovet P |
|
Bovet |
Pascal |
P |
|
|
Burnier M |
|
Burnier |
Michel |
M |
|
|
Campbell H |
|
Campbell |
Harry |
H |
|
|
Chakravarti A |
|
Chakravarti |
Aravinda |
A |
|
|
Chambers JC |
|
Chambers |
John C |
JC |
|
|
Chen YD |
|
Chen |
Yii-Der Ida |
YD |
|
|
Collins FS |
|
Collins |
Francis S |
FS |
|
|
Cooper RS |
|
Cooper |
Richard S |
RS |
|
|
Danesh J |
|
Danesh |
John |
J |
|
|
Dedoussis G |
|
Dedoussis |
George |
G |
|
|
de Faire U |
|
de Faire |
Ulf |
U |
|
|
Feranil AB |
|
Feranil |
Alan B |
AB |
|
|
Ferrières J |
|
Ferrières |
Jean |
J |
|
|
Ferrucci L |
|
Ferrucci |
Luigi |
L |
|
|
Freimer NB |
|
Freimer |
Nelson B |
NB |
|
|
Gieger C |
|
Gieger |
Christian |
C |
|
|
Groop LC |
|
Groop |
Leif C |
LC |
|
|
Gudnason V |
|
Gudnason |
Vilmundur |
V |
|
|
Gyllensten U |
|
Gyllensten |
Ulf |
U |
|
|
Hamsten A |
|
Hamsten |
Anders |
A |
|
|
Harris TB |
|
Harris |
Tamara B |
TB |
|
|
Hingorani A |
|
Hingorani |
Aroon |
A |
|
|
Hirschhorn JN |
|
Hirschhorn |
Joel N |
JN |
|
|
Hofman A |
|
Hofman |
Albert |
A |
|
|
Hovingh GK |
|
Hovingh |
G Kees |
GK |
|
|
Hsiung CA |
|
Hsiung |
Chao Agnes |
CA |
|
|
Humphries SE |
|
Humphries |
Steve E |
SE |
|
|
Hunt SC |
|
Hunt |
Steven C |
SC |
|
|
Hveem K |
|
Hveem |
Kristian |
K |
|
|
Iribarren C |
|
Iribarren |
Carlos |
C |
|
|
Järvelin MR |
|
Järvelin |
Marjo-Riitta |
MR |
|
|
Jula A |
|
Jula |
Antti |
A |
|
|
Kähönen M |
|
Kähönen |
Mika |
M |
|
|
Kaprio J |
|
Kaprio |
Jaakko |
J |
|
|
Kesäniemi A |
|
Kesäniemi |
Antero |
A |
|
|
Kivimaki M |
|
Kivimaki |
Mika |
M |
|
|
Kooner JS |
|
Kooner |
Jaspal S |
JS |
|
|
Koudstaal PJ |
|
Koudstaal |
Peter J |
PJ |
|
|
Krauss RM |
|
Krauss |
Ronald M |
RM |
|
|
Kuh D |
|
Kuh |
Diana |
D |
|
|
Kuusisto J |
|
Kuusisto |
Johanna |
J |
|
|
Kyvik KO |
|
Kyvik |
Kirsten O |
KO |
|
|
Laakso M |
|
Laakso |
Markku |
M |
|
|
Lakka TA |
|
Lakka |
Timo A |
TA |
|
|
Lind L |
|
Lind |
Lars |
L |
|
|
Lindgren CM |
|
Lindgren |
Cecilia M |
CM |
|
|
Martin NG |
|
Martin |
Nicholas G |
NG |
|
|
März W |
|
März |
Winfried |
W |
|
|
McCarthy MI |
|
McCarthy |
Mark I |
MI |
|
|
McKenzie CA |
|
McKenzie |
Colin A |
CA |
|
|
Meneton P |
|
Meneton |
Pierre |
P |
|
|
Metspalu A |
|
Metspalu |
Andres |
A |
|
|
Moilanen L |
|
Moilanen |
Leena |
L |
|
|
Morris AD |
|
Morris |
Andrew D |
AD |
|
|
Munroe PB |
|
Munroe |
Patricia B |
PB |
|
|
Njølstad I |
|
Njølstad |
Inger |
I |
|
|
Pedersen NL |
|
Pedersen |
Nancy L |
NL |
|
|
Power C |
|
Power |
Chris |
C |
|
|
Pramstaller PP |
|
Pramstaller |
Peter P |
PP |
|
|
Price JF |
|
Price |
Jackie F |
JF |
|
|
Psaty BM |
|
Psaty |
Bruce M |
BM |
|
|
Quertermous T |
|
Quertermous |
Thomas |
T |
|
|
Rauramaa R |
|
Rauramaa |
Rainer |
R |
|
|
Saleheen D |
|
Saleheen |
Danish |
D |
|
|
Salomaa V |
|
Salomaa |
Veikko |
V |
|
|
Sanghera DK |
|
Sanghera |
Dharambir K |
DK |
|
|
Saramies J |
|
Saramies |
Jouko |
J |
|
|
Schwarz PE |
|
Schwarz |
Peter E H |
PE |
|
|
Sheu WH |
|
Sheu |
Wayne H-H |
WH |
|
|
Shuldiner AR |
|
Shuldiner |
Alan R |
AR |
|
|
Siegbahn A |
|
Siegbahn |
Agneta |
A |
|
|
Spector TD |
|
Spector |
Tim D |
TD |
|
|
Stefansson K |
|
Stefansson |
Kari |
K |
|
|
Strachan DP |
|
Strachan |
David P |
DP |
|
|
Tayo BO |
|
Tayo |
Bamidele O |
BO |
|
|
Tremoli E |
|
Tremoli |
Elena |
E |
|
|
Tuomilehto J |
|
Tuomilehto |
Jaakko |
J |
|
|
Uusitupa M |
|
Uusitupa |
Matti |
M |
|
|
van Duijn CM |
|
van Duijn |
Cornelia M |
CM |
|
|
Vollenweider P |
|
Vollenweider |
Peter |
P |
|
|
Wallentin L |
|
Wallentin |
Lars |
L |
|
|
Wareham NJ |
|
Wareham |
Nicholas J |
NJ |
|
|
Whitfield JB |
|
Whitfield |
John B |
JB |
|
|
Wolffenbuttel BH |
|
Wolffenbuttel |
Bruce H R |
BH |
|
|
Altshuler D |
|
Altshuler |
David |
D |
|
|
Ordovas JM |
|
Ordovas |
Jose M |
JM |
|
|
Boerwinkle E |
|
Boerwinkle |
Eric |
E |
|
|
Palmer CN |
|
Palmer |
Colin N A |
CN |
|
|
Thorsteinsdottir U |
|
Thorsteinsdottir |
Unnur |
U |
|
|
Chasman DI |
|
Chasman |
Daniel I |
DI |
|
|
Rotter JI |
|
Rotter |
Jerome I |
JI |
|
|
Franks PW |
|
Franks |
Paul W |
PW |
|
|
Ripatti S |
|
Ripatti |
Samuli |
S |
|
|
Cupples LA |
|
Cupples |
L Adrienne |
LA |
|
|
Sandhu MS |
|
Sandhu |
Manjinder S |
MS |
|
|
Rich SS |
|
Rich |
Stephen S |
SS |
|
|
Boehnke M |
|
Boehnke |
Michael |
M |
|
|
Deloukas P |
|
Deloukas |
Panos |
P |
|
|
Mohlke KL |
|
Mohlke |
Karen L |
KL |
|
|
Ingelsson E |
|
Ingelsson |
Erik |
E |
|
|
Abecasis GR |
|
Abecasis |
Goncalo R |
GR |
|
|
Daly MJ |
|
Daly |
Mark J |
MJ |
|
|
Neale BM |
|
Neale |
Benjamin M |
BM |
|
|
Kathiresan S |
|
Kathiresan |
Sekar |
S |
|
|
|
INVESTIGATORS |
|
|
JOURNAL |
|
VOLUME: 45 |
ISSUE: 11 |
TITLE: Nature genetics |
ISOABBREVIATION: Nat. Genet. |
YEAR: 2013 |
MONTH: Nov |
DAY: |
MEDLINEDATE: |
SEASON: |
CITEDMEDIUM: Internet |
ISSN: 1546-1718 |
ISSNTYPE: Electronic |
|
MEDLINE JOURNAL |
|
MEDLINETA: Nat Genet |
COUNTRY: United States |
ISSNLINKING: 1061-4036 |
NLMUNIQUEID: 9216904 |
|
PUBLICATION TYPE |
|
PUBLICATIONTYPE TEXT |
Journal Article |
Research Support, N.I.H., Extramural |
Research Support, Non-U.S. Gov't |
|
COMMENTS AND CORRECTIONS |
|
REFTYPE |
REFSOURCE |
REFPMID |
NOTE |
Cites |
N Engl J Med. 1999 Aug 5;341(6):410-8 |
10438259 |
|
Cites |
Nat Genet. 2013 Nov;45(11):1274-83 |
24097068 |
|
Cites |
N Engl J Med. 2006 Mar 23;354(12):1264-72 |
16554528 |
|
Cites |
Circulation. 2007 Jan 30;115(4):450-8 |
17190864 |
|
Cites |
PLoS Med. 2007 Dec;4(12):e352 |
18076282 |
|
Cites |
Nat Genet. 2008 Feb;40(2):161-9 |
18193043 |
|
Cites |
Nat Genet. 2008 Feb;40(2):189-97 |
18193044 |
|
Cites |
Hum Genet. 2008 Feb;123(1):15-33 |
18038153 |
|
Cites |
JAMA. 2008 Jun 4;299(21):2524-32 |
18523221 |
|
Cites |
PLoS Med. 2008 Aug 26;5(8):e177 |
18752343 |
|
Cites |
Science. 2008 Dec 12;322(5908):1702-5 |
19074352 |
|
Cites |
Nat Genet. 2009 Jan;41(1):56-65 |
19060906 |
|
Cites |
J Clin Endocrinol Metab. 2009 Apr;94(4):1264-73 |
19088157 |
|
Cites |
JAMA. 2009 Nov 11;302(18):1993-2000 |
19903920 |
|
Cites |
Circ Cardiovasc Genet. 2010 Feb;3(1):109-17 |
20160203 |
|
Cites |
N Engl J Med. 2010 Apr 29;362(17):1563-74 |
20228404 |
|
Cites |
Science. 2001 Oct 5;294(5540):169-73 |
11588264 |
|
Cites |
Int J Epidemiol. 2003 Feb;32(1):1-22 |
12689998 |
|
Cites |
Int J Epidemiol. 2004 Feb;33(1):30-42 |
15075143 |
|
Cites |
Lancet. 1997 May 17;349(9063):1436-42 |
9164317 |
|
Cites |
Circulation. 1998 May 12;97(18):1837-47 |
9603539 |
|
Cites |
Lancet. 2010 May 8;375(9726):1634-9 |
20452521 |
|
Cites |
Nature. 2010 Aug 5;466(7307):707-13 |
20686565 |
|
Cites |
Nature. 2010 Oct 28;467(7319):1061-73 |
20981092 |
|
Cites |
J Clin Endocrinol Metab. 2010 Dec;95(12):E500-10 |
20826588 |
|
Cites |
Nat Genet. 2011 Apr;43(4):333-8 |
21378990 |
|
Cites |
Circulation. 2011 May 24;123(20):2292-333 |
21502576 |
|
Cites |
J Clin Endocrinol Metab. 2012 Feb;97(2):E248-56 |
22090275 |
|
Cites |
N Engl J Med. 2012 Jul 26;367(4):309-18 |
22686415 |
|
Cites |
Lancet. 2012 Aug 11;380(9841):572-80 |
22607825 |
|
Cites |
Nat Genet. 2013 Jan;45(1):25-33 |
23202125 |
|
Cites |
J Am Coll Cardiol. 2013 Jan 29;61(4):427-36 |
23265341 |
|
Cites |
Lancet. 2005 Nov 26;366(9500):1849-61 |
16310551 |
|
|
GRANTS |
|
GRANTID |
AGENCY |
COUNTRY |
090532 |
Wellcome Trust |
United Kingdom |
CZB/4/672 |
Chief Scientist Office |
United Kingdom |
CZB/4/710 |
Chief Scientist Office |
United Kingdom |
G0701863 |
Medical Research Council |
United Kingdom |
G0901213 |
Medical Research Council |
United Kingdom |
G1000143 |
Medical Research Council |
United Kingdom |
MC_U106179471 |
Medical Research Council |
United Kingdom |
MC_U106179472 |
Medical Research Council |
United Kingdom |
MC_U106188470 |
Medical Research Council |
United Kingdom |
MC_U123092720 |
Medical Research Council |
United Kingdom |
MC_U950080926 |
Medical Research Council |
United Kingdom |
MR/K013351/1 |
Medical Research Council |
United Kingdom |
MR/K013491/1 |
Medical Research Council |
United Kingdom |
MR/L003120/1 |
Medical Research Council |
United Kingdom |
P30 DK063491 |
NIDDK NIH HHS |
United States |
P60 DK020541 |
NIDDK NIH HHS |
United States |
PG/08/094/26019 |
British Heart Foundation |
United Kingdom |
R01 DK072193 |
NIDDK NIH HHS |
United States |
R01 HL105756 |
NHLBI NIH HHS |
United States |
R01 HL107816 |
NHLBI NIH HHS |
United States |
R01 HL109946 |
NHLBI NIH HHS |
United States |
R01HL107816 |
NHLBI NIH HHS |
United States |
RG/08/014/24067 |
British Heart Foundation |
United Kingdom |
T32HL007208 |
NHLBI NIH HHS |
United States |
U01 HL069757 |
NHLBI NIH HHS |
United States |
UL1 TR000124 |
NCATS NIH HHS |
United States |
|
Canadian Institutes of Health Research |
Canada |
|
GENERAL NOTE |
|
|
KEYWORDS |
|
|
MESH HEADINGS |
|
DESCRIPTORNAME |
QUALIFIERNAME |
Biological Transport |
|
Cholesterol, HDL |
genetics |
Cholesterol, LDL |
genetics |
Coronary Artery Disease |
genetics |
Humans |
genetics |
Polymorphism, Single Nucleotide |
genetics |
Risk Factors |
genetics |
Triglycerides |
metabolism |
|
SUPPLEMENTARY MESH |
|
|
GENE SYMBOLS |
|
|
CHEMICALS |
|
REGISTRYNUMBER |
NAMEOFSUBSTANCE |
0 |
Cholesterol, HDL |
0 |
Cholesterol, LDL |
0 |
Triglycerides |
|
OTHER ID's |
|
OTHERID |
SOURCE |
NIHMS524704 |
NLM |
PMC3904346 |
NLM |
|
|