|
|
| PMID |
|
|
| TITLE |
|
| Substance use and sexual intercourse onsets in adolescence: a genetically informative discordant twin design. |
|
| ABSTRACT |
|
| PURPOSE |
NlmCategory: OBJECTIVE |
| Using a genetically informed, discordant twin analysis, the objective of this study was to examine whether earlier onset of drinking and smoking behaviors predicted early sexual intercourse onset. |
| METHODS |
NlmCategory: METHODS |
| Over 3,400 adult same-sex twins from the Australian Twin Registry completed a structured interview that included retrospective reports on onsets of smoking, drinking, intoxication, and sexual intercourse and conduct disorder symptoms. A two-level frailty model estimated within-twin-pair and between-twin-pair comparisons. Onsets of smoking, drinking, drunkenness, and conduct disorder symptoms were estimated as sexual intercourse onset predictors. |
| RESULTS |
NlmCategory: RESULTS |
| After controlling for conduct disorder, smoking and drinking onset did not predict sexual intercourse onset for either within-twin-pair or between-twin-pair comparisons. Drunkenness onset had a significant effect on sexual intercourse onset, such that twins who first experienced alcohol intoxication at a younger age than their co-twins were also more likely to have sex earlier than their co-twins. |
| CONCLUSIONS |
NlmCategory: CONCLUSIONS |
| Relationships between substance use and sexual intercourse onsets may be due mostly to shared underlying factors; there was only a small relation between intoxication onset and sexual intercourse onset, and no direct relation between smoking and drinking onset and sexual intercourse onset. |
| Copyright © 2014 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved. |
|
| DATE PUBLISHED |
|
|
| HISTORY |
|
| PUBSTATUS |
PUBSTATUSDATE |
| received |
2013/03/26 |
| revised |
2013/07/05 |
| accepted |
2013/07/11 |
| aheadofprint |
2013/08/29 |
| entrez |
2013/09/03 06:00 |
| pubmed |
2013/09/03 06:00 |
| medline |
2014/08/08 06:00 |
|
| AUTHORS |
|
| NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
| Deutsch AR |
|
Deutsch |
Arielle R |
AR |
|
Department of Psychological Sciences, University of Missouri-Columbia, Columbia, Missouri; Midwest Alcohol Research Center, Columbia, Missouri. Electronic address: arielle.deutsch@gmail.com. |
| Slutske WS |
|
Slutske |
Wendy S |
WS |
|
Department of Psychological Sciences, University of Missouri-Columbia, Columbia, Missouri; Midwest Alcohol Research Center, Columbia, Missouri. |
| Heath AC |
|
Heath |
Andrew C |
AC |
|
Midwest Alcohol Research Center, Columbia, Missouri; Department of Psychiatry, Washington University, St. Louis, Missouri. |
| Madden PA |
|
Madden |
Pamela A F |
PA |
|
Midwest Alcohol Research Center, Columbia, Missouri; Department of Psychiatry, Washington University, St. Louis, Missouri. |
| Martin NG |
|
Martin |
Nicholas G |
NG |
|
Queensland Institute of Medical Research, Brisbane, Australia. |
|
| INVESTIGATORS |
|
|
| JOURNAL |
|
| VOLUME: 54 |
| ISSUE: 1 |
| TITLE: The Journal of adolescent health : official publication of the Society for Adolescent Medicine |
| ISOABBREVIATION: J Adolesc Health |
| YEAR: 2014 |
| MONTH: Jan |
| DAY: |
| MEDLINEDATE: |
| SEASON: |
| CITEDMEDIUM: Internet |
| ISSN: 1879-1972 |
| ISSNTYPE: Electronic |
|
| MEDLINE JOURNAL |
|
| MEDLINETA: J Adolesc Health |
| COUNTRY: United States |
| ISSNLINKING: 1054-139X |
| NLMUNIQUEID: 9102136 |
|
| PUBLICATION TYPE |
|
| PUBLICATIONTYPE TEXT |
| Journal Article |
| Twin Study |
|
| COMMENTS AND CORRECTIONS |
|
| REFTYPE |
REFSOURCE |
REFPMID |
NOTE |
| Cites |
J Adolesc Health. 2005 Jan;36(1):82-6 |
15661605 |
|
| Cites |
Psychol Med. 2004 Nov;34(8):1519-30 |
15724882 |
|
| Cites |
Psychol Methods. 2007 Jun;12(2):121-38 |
17563168 |
|
| Cites |
Genes Brain Behav. 2009 Feb;8(1):107-13 |
19016887 |
|
| Cites |
Behav Genet. 2010 Jan;40(1):12-21 |
19813084 |
|
| Cites |
J Adolesc Health. 2010 Oct;47(4):389-98 |
20864009 |
|
| Cites |
Arch Sex Behav. 2013 Jan;42(1):35-44 |
22441771 |
|
| CommentIn |
J Adolesc Health. 2014 Jan;54(1):1-2 |
24360592 |
|
|
| GRANTS |
|
| GRANTID |
AGENCY |
COUNTRY |
| K05 AA017688 |
NIAAA NIH HHS |
United States |
| R37 AA007728 |
NIAAA NIH HHS |
United States |
|
| GENERAL NOTE |
|
|
| KEYWORDS |
|
| KEYWORD |
| Problem behavior theory |
| Sexual intercourse onset |
| Substance use onset |
| Twin study |
|
| MESH HEADINGS |
|
| DESCRIPTORNAME |
QUALIFIERNAME |
| Adult |
|
| Age of Onset |
|
| Alcoholic Intoxication |
genetics |
| Coitus |
genetics |
| Female |
genetics |
| Humans |
genetics |
| Male |
genetics |
| Retrospective Studies |
genetics |
| Risk Factors |
genetics |
| Smoking |
genetics |
| Substance-Related Disorders |
genetics |
| Twins |
genetics |
|
| SUPPLEMENTARY MESH |
|
|
| GENE SYMBOLS |
|
|
| CHEMICALS |
|
|
| OTHER ID's |
|
| OTHERID |
SOURCE |
| NIHMS521675 |
NLM |
| PMC3872214 |
NLM |
|
|
