Genetic Epidemiology, Psychiatric Genetics, Asthma Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
QIMR Home Page
GenEpi Home Page
Publications
Contacts
Research
Staff Index
Collaborators
Software Tools
Computing Resources
Studies
Search
GenEpi Intranet
PMID
23933821
TITLE
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.
ABSTRACT
Most psychiatric disorders are moderately to highly heritable. The degree to which genetic variation is unique to individual disorders or shared across disorders is unclear. To examine shared genetic etiology, we use genome-wide genotype data from the Psychiatric Genomics Consortium (PGC) for cases and controls in schizophrenia, bipolar disorder, major depressive disorder, autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD). We apply univariate and bivariate methods for the estimation of genetic variation within and covariation between disorders. SNPs explained 17-29% of the variance in liability. The genetic correlation calculated using common SNPs was high between schizophrenia and bipolar disorder (0.68 ± 0.04 s.e.), moderate between schizophrenia and major depressive disorder (0.43 ± 0.06 s.e.), bipolar disorder and major depressive disorder (0.47 ± 0.06 s.e.), and ADHD and major depressive disorder (0.32 ± 0.07 s.e.), low between schizophrenia and ASD (0.16 ± 0.06 s.e.) and non-significant for other pairs of disorders as well as between psychiatric disorders and the negative control of Crohn's disease. This empirical evidence of shared genetic etiology for psychiatric disorders can inform nosology and encourages the investigation of common pathophysiologies for related disorders.
DATE PUBLISHED
2013 Sep
HISTORY
PUBSTATUS PUBSTATUSDATE
received 2013/02/10
accepted 2013/06/28
aheadofprint 2013/08/11
entrez 2013/08/13 06:00
pubmed 2013/08/13 06:00
medline 2013/12/16 06:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Cross-Disorder Group of the Psychiatric Genomics Consortium The University of Queensland, Queensland Brain Institute, Brisbane, Queensland, Australia.
Lee SH Lee S Hong SH
Ripke S Ripke Stephan S
Neale BM Neale Benjamin M BM
Faraone SV Faraone Stephen V SV
Purcell SM Purcell Shaun M SM
Perlis RH Perlis Roy H RH
Mowry BJ Mowry Bryan J BJ
Thapar A Thapar Anita A
Goddard ME Goddard Michael E ME
Witte JS Witte John S JS
Absher D Absher Devin D
Agartz I Agartz Ingrid I
Akil H Akil Huda H
Amin F Amin Farooq F
Andreassen OA Andreassen Ole A OA
Anjorin A Anjorin Adebayo A
Anney R Anney Richard R
Anttila V Anttila Verneri V
Arking DE Arking Dan E DE
Asherson P Asherson Philip P
Azevedo MH Azevedo Maria H MH
Backlund L Backlund Lena L
Badner JA Badner Judith A JA
Bailey AJ Bailey Anthony J AJ
Banaschewski T Banaschewski Tobias T
Barchas JD Barchas Jack D JD
Barnes MR Barnes Michael R MR
Barrett TB Barrett Thomas B TB
Bass N Bass Nicholas N
Battaglia A Battaglia Agatino A
Bauer M Bauer Michael M
Bayés M Bayés Mònica M
Bellivier F Bellivier Frank F
Bergen SE Bergen Sarah E SE
Berrettini W Berrettini Wade W
Betancur C Betancur Catalina C
Bettecken T Bettecken Thomas T
Biederman J Biederman Joseph J
Binder EB Binder Elisabeth B EB
Black DW Black Donald W DW
Blackwood DH Blackwood Douglas H R DH
Bloss CS Bloss Cinnamon S CS
Boehnke M Boehnke Michael M
Boomsma DI Boomsma Dorret I DI
Breen G Breen Gerome G
Breuer R Breuer René R
Bruggeman R Bruggeman Richard R
Cormican P Cormican Paul P
Buccola NG Buccola Nancy G NG
Buitelaar JK Buitelaar Jan K JK
Bunney WE Bunney William E WE
Buxbaum JD Buxbaum Joseph D JD
Byerley WF Byerley William F WF
Byrne EM Byrne Enda M EM
Caesar S Caesar Sian S
Cahn W Cahn Wiepke W
Cantor RM Cantor Rita M RM
Casas M Casas Miguel M
Chakravarti A Chakravarti Aravinda A
Chambert K Chambert Kimberly K
Choudhury K Choudhury Khalid K
Cichon S Cichon Sven S
Cloninger CR Cloninger C Robert CR
Collier DA Collier David A DA
Cook EH Cook Edwin H EH
Coon H Coon Hilary H
Cormand B Cormand Bru B
Corvin A Corvin Aiden A
Coryell WH Coryell William H WH
Craig DW Craig David W DW
Craig IW Craig Ian W IW
Crosbie J Crosbie Jennifer J
Cuccaro ML Cuccaro Michael L ML
Curtis D Curtis David D
Czamara D Czamara Darina D
Datta S Datta Susmita S
Dawson G Dawson Geraldine G
Day R Day Richard R
De Geus EJ De Geus Eco J EJ
Degenhardt F Degenhardt Franziska F
Djurovic S Djurovic Srdjan S
Donohoe GJ Donohoe Gary J GJ
Doyle AE Doyle Alysa E AE
Duan J Duan Jubao J
Dudbridge F Dudbridge Frank F
Duketis E Duketis Eftichia E
Ebstein RP Ebstein Richard P RP
Edenberg HJ Edenberg Howard J HJ
Elia J Elia Josephine J
Ennis S Ennis Sean S
Etain B Etain Bruno B
Fanous A Fanous Ayman A
Farmer AE Farmer Anne E AE
Ferrier IN Ferrier I Nicol IN
Flickinger M Flickinger Matthew M
Fombonne E Fombonne Eric E
Foroud T Foroud Tatiana T
Frank J Frank Josef J
Franke B Franke Barbara B
Fraser C Fraser Christine C
Freedman R Freedman Robert R
Freimer NB Freimer Nelson B NB
Freitag CM Freitag Christine M CM
Friedl M Friedl Marion M
Frisén L Frisén Louise L
Gallagher L Gallagher Louise L
Gejman PV Gejman Pablo V PV
Georgieva L Georgieva Lyudmila L
Gershon ES Gershon Elliot S ES
Geschwind DH Geschwind Daniel H DH
Giegling I Giegling Ina I
Gill M Gill Michael M
Gordon SD Gordon Scott D SD
Gordon-Smith K Gordon-Smith Katherine K
Green EK Green Elaine K EK
Greenwood TA Greenwood Tiffany A TA
Grice DE Grice Dorothy E DE
Gross M Gross Magdalena M
Grozeva D Grozeva Detelina D
Guan W Guan Weihua W
Gurling H Gurling Hugh H
De Haan L De Haan Lieuwe L
Haines JL Haines Jonathan L JL
Hakonarson H Hakonarson Hakon H
Hallmayer J Hallmayer Joachim J
Hamilton SP Hamilton Steven P SP
Hamshere ML Hamshere Marian L ML
Hansen TF Hansen Thomas F TF
Hartmann AM Hartmann Annette M AM
Hautzinger M Hautzinger Martin M
Heath AC Heath Andrew C AC
Henders AK Henders Anjali K AK
Herms S Herms Stefan S
Hickie IB Hickie Ian B IB
Hipolito M Hipolito Maria M
Hoefels S Hoefels Susanne S
Holmans PA Holmans Peter A PA
Holsboer F Holsboer Florian F
Hoogendijk WJ Hoogendijk Witte J WJ
Hottenga JJ Hottenga Jouke-Jan JJ
Hultman CM Hultman Christina M CM
Hus V Hus Vanessa V
Ingason A Ingason Andrés A
Ising M Ising Marcus M
Jamain S Jamain Stéphane S
Jones EG Jones Edward G EG
Jones I Jones Ian I
Jones L Jones Lisa L
Tzeng JY Tzeng Jung-Ying JY
Kähler AK Kähler Anna K AK
Kahn RS Kahn René S RS
Kandaswamy R Kandaswamy Radhika R
Keller MC Keller Matthew C MC
Kennedy JL Kennedy James L JL
Kenny E Kenny Elaine E
Kent L Kent Lindsey L
Kim Y Kim Yunjung Y
Kirov GK Kirov George K GK
Klauck SM Klauck Sabine M SM
Klei L Klei Lambertus L
Knowles JA Knowles James A JA
Kohli MA Kohli Martin A MA
Koller DL Koller Daniel L DL
Konte B Konte Bettina B
Korszun A Korszun Ania A
Krabbendam L Krabbendam Lydia L
Krasucki R Krasucki Robert R
Kuntsi J Kuntsi Jonna J
Kwan P Kwan Phoenix P
Landén M Landén Mikael M
Långström N Långström Niklas N
Lathrop M Lathrop Mark M
Lawrence J Lawrence Jacob J
Lawson WB Lawson William B WB
Leboyer M Leboyer Marion M
Ledbetter DH Ledbetter David H DH
Lee PH Lee Phil H PH
Lencz T Lencz Todd T
Lesch KP Lesch Klaus-Peter KP
Levinson DF Levinson Douglas F DF
Lewis CM Lewis Cathryn M CM
Li J Li Jun J
Lichtenstein P Lichtenstein Paul P
Lieberman JA Lieberman Jeffrey A JA
Lin DY Lin Dan-Yu DY
Linszen DH Linszen Don H DH
Liu C Liu Chunyu C
Lohoff FW Lohoff Falk W FW
Loo SK Loo Sandra K SK
Lord C Lord Catherine C
Lowe JK Lowe Jennifer K JK
Lucae S Lucae Susanne S
MacIntyre DJ MacIntyre Donald J DJ
Madden PA Madden Pamela A F PA
Maestrini E Maestrini Elena E
Magnusson PK Magnusson Patrik K E PK
Mahon PB Mahon Pamela B PB
Maier W Maier Wolfgang W
Malhotra AK Malhotra Anil K AK
Mane SM Mane Shrikant M SM
Martin CL Martin Christa L CL
Martin NG Martin Nicholas G NG
Mattheisen M Mattheisen Manuel M
Matthews K Matthews Keith K
Mattingsdal M Mattingsdal Morten M
McCarroll SA McCarroll Steven A SA
McGhee KA McGhee Kevin A KA
McGough JJ McGough James J JJ
McGrath PJ McGrath Patrick J PJ
McGuffin P McGuffin Peter P
McInnis MG McInnis Melvin G MG
McIntosh A McIntosh Andrew A
McKinney R McKinney Rebecca R
McLean AW McLean Alan W AW
McMahon FJ McMahon Francis J FJ
McMahon WM McMahon William M WM
McQuillin A McQuillin Andrew A
Medeiros H Medeiros Helena H
Medland SE Medland Sarah E SE
Meier S Meier Sandra S
Melle I Melle Ingrid I
Meng F Meng Fan F
Meyer J Meyer Jobst J
Middeldorp CM Middeldorp Christel M CM
Middleton L Middleton Lefkos L
Milanova V Milanova Vihra V
Miranda A Miranda Ana A
Monaco AP Monaco Anthony P AP
Montgomery GW Montgomery Grant W GW
Moran JL Moran Jennifer L JL
Moreno-De-Luca D Moreno-De-Luca Daniel D
Morken G Morken Gunnar G
Morris DW Morris Derek W DW
Morrow EM Morrow Eric M EM
Moskvina V Moskvina Valentina V
Muglia P Muglia Pierandrea P
Mühleisen TW Mühleisen Thomas W TW
Muir WJ Muir Walter J WJ
Müller-Myhsok B Müller-Myhsok Bertram B
Murtha M Murtha Michael M
Myers RM Myers Richard M RM
Myin-Germeys I Myin-Germeys Inez I
Neale MC Neale Michael C MC
Nelson SF Nelson Stan F SF
Nievergelt CM Nievergelt Caroline M CM
Nikolov I Nikolov Ivan I
Nimgaonkar V Nimgaonkar Vishwajit V
Nolen WA Nolen Willem A WA
Nöthen MM Nöthen Markus M MM
Nurnberger JI Nurnberger John I JI
Nwulia EA Nwulia Evaristus A EA
Nyholt DR Nyholt Dale R DR
O'Dushlaine C O'Dushlaine Colm C
Oades RD Oades Robert D RD
Olincy A Olincy Ann A
Oliveira G Oliveira Guiomar G
Olsen L Olsen Line L
Ophoff RA Ophoff Roel A RA
Osby U Osby Urban U
Owen MJ Owen Michael J MJ
Palotie A Palotie Aarno A
Parr JR Parr Jeremy R JR
Paterson AD Paterson Andrew D AD
Pato CN Pato Carlos N CN
Pato MT Pato Michele T MT
Penninx BW Penninx Brenda W BW
Pergadia ML Pergadia Michele L ML
Pericak-Vance MA Pericak-Vance Margaret A MA
Pickard BS Pickard Benjamin S BS
Pimm J Pimm Jonathan J
Piven J Piven Joseph J
Posthuma D Posthuma Danielle D
Potash JB Potash James B JB
Poustka F Poustka Fritz F
Propping P Propping Peter P
Puri V Puri Vinay V
Quested DJ Quested Digby J DJ
Quinn EM Quinn Emma M EM
Ramos-Quiroga JA Ramos-Quiroga Josep Antoni JA
Rasmussen HB Rasmussen Henrik B HB
Raychaudhuri S Raychaudhuri Soumya S
Rehnström K Rehnström Karola K
Reif A Reif Andreas A
Ribasés M Ribasés Marta M
Rice JP Rice John P JP
Rietschel M Rietschel Marcella M
Roeder K Roeder Kathryn K
Roeyers H Roeyers Herbert H
Rossin L Rossin Lizzy L
Rothenberger A Rothenberger Aribert A
Rouleau G Rouleau Guy G
Ruderfer D Ruderfer Douglas D
Rujescu D Rujescu Dan D
Sanders AR Sanders Alan R AR
Sanders SJ Sanders Stephan J SJ
Santangelo SL Santangelo Susan L SL
Sergeant JA Sergeant Joseph A JA
Schachar R Schachar Russell R
Schalling M Schalling Martin M
Schatzberg AF Schatzberg Alan F AF
Scheftner WA Scheftner William A WA
Schellenberg GD Schellenberg Gerard D GD
Scherer SW Scherer Stephen W SW
Schork NJ Schork Nicholas J NJ
Schulze TG Schulze Thomas G TG
Schumacher J Schumacher Johannes J
Schwarz M Schwarz Markus M
Scolnick E Scolnick Edward E
Scott LJ Scott Laura J LJ
Shi J Shi Jianxin J
Shilling PD Shilling Paul D PD
Shyn SI Shyn Stanley I SI
Silverman JM Silverman Jeremy M JM
Slager SL Slager Susan L SL
Smalley SL Smalley Susan L SL
Smit JH Smit Johannes H JH
Smith EN Smith Erin N EN
Sonuga-Barke EJ Sonuga-Barke Edmund J S EJ
St Clair D St Clair David D
State M State Matthew M
Steffens M Steffens Michael M
Steinhausen HC Steinhausen Hans-Christoph HC
Strauss JS Strauss John S JS
Strohmaier J Strohmaier Jana J
Stroup TS Stroup T Scott TS
Sutcliffe JS Sutcliffe James S JS
Szatmari P Szatmari Peter P
Szelinger S Szelinger Szabocls S
Thirumalai S Thirumalai Srinivasa S
Thompson RC Thompson Robert C RC
Todorov AA Todorov Alexandre A AA
Tozzi F Tozzi Federica F
Treutlein J Treutlein Jens J
Uhr M Uhr Manfred M
van den Oord EJ van den Oord Edwin J C G EJ
Van Grootheest G Van Grootheest Gerard G
Van Os J Van Os Jim J
Vicente AM Vicente Astrid M AM
Vieland VJ Vieland Veronica J VJ
Vincent JB Vincent John B JB
Visscher PM Visscher Peter M PM
Walsh CA Walsh Christopher A CA
Wassink TH Wassink Thomas H TH
Watson SJ Watson Stanley J SJ
Weissman MM Weissman Myrna M MM
Werge T Werge Thomas T
Wienker TF Wienker Thomas F TF
Wijsman EM Wijsman Ellen M EM
Willemsen G Willemsen Gonneke G
Williams N Williams Nigel N
Willsey AJ Willsey A Jeremy AJ
Witt SH Witt Stephanie H SH
Xu W Xu Wei W
Young AH Young Allan H AH
Yu TW Yu Timothy W TW
Zammit S Zammit Stanley S
Zandi PP Zandi Peter P PP
Zhang P Zhang Peng P
Zitman FG Zitman Frans G FG
Zöllner S Zöllner Sebastian S
Devlin B Devlin Bernie B
Kelsoe JR Kelsoe John R JR
Sklar P Sklar Pamela P
Daly MJ Daly Mark J MJ
O'Donovan MC O'Donovan Michael C MC
Craddock N Craddock Nicholas N
Sullivan PF Sullivan Patrick F PF
Smoller JW Smoller Jordan W JW
Kendler KS Kendler Kenneth S KS
Wray NR Wray Naomi R NR
International Inflammatory Bowel Disease Genetics Consortium (IIBDGC)
INVESTIGATORS
LASTNAME FORENAME INITIALS AFFILIATION
Abraham Clara C
Achkar Jean-Paul JP
Ahmad Tariq T
Amininejad Leila L
Anathakrishnan Ashwin N AN
Andersen Vibeke V
Anderson Carl A CA
Andrews Jane M JM
Annese Vito V
Baidoo Leonard L
Balshun Tobias T
Bampton Peter A PA
Barrett Jeffrey C JC
Bitton Alain A
Boucher Gabrielle G
Brand Stephan S
Brant Steven R SR
Büning Carsten C
Cho Judy H JH
Cichon Sven S
Cleynen Isabelle I
Cohain Ariella A
D'Amato Mauro M
Daly Mark J MJ
Dejong Dirk D
Devaney Kathy L KL
DeVos Martine M
Dubinsky Marla M
Duerr Richard H RH
Edwards Cathryn C
Ellinghaus David D
Essers Jonah J
Ferguson Lynnette R LR
Franchimont Denis D
Franke Andre A
Fransen Karin K
Gearry Richard R
Georges Michel M
Gieger Christian C
Glas Jürgen J
Goyette Philippe P
Hakonarson Hakon H
Haritunians Talin T
Hart Alisa A
Hawkey Chris C
Hedl Matija M
Hu Xinli X
Hui Ken Y KY
Jostins Luke L
Karlsen Tom H TH
Kugathasan Subra S
Kupcinskas Limas L
Latiano Anna A
Laukens Debby D
Lawrance Ian C IC
Lee James C JC
Lees Charles W CW
Louis Edouard E
Mahy Gillian G
Mansfield John J
Mathew Christopher G CG
McGovern Dermot P DP
Mitrovic Mitja M
Morgan Angharad R AR
Mowat Craig C
Newman William W
Ning Kaida K
Palmieri Orazio O
Parkes Miles M
Ponsioen Cyriel Y CY
Potocnik Uros U
Prescott Natalie J NJ
Radford-Smith Graham G
Raychaudhuri Soumya S
Regueiro Miguel M
Rioux John D JD
Ripke Stephan S
Rotter Jerome I JI
Russell Richard K RK
Sanderson Jeremy D JD
Sans Miquel M
Satsangi Jack J
Schadt Eric E EE
Schreiber Stefan S
Schumm L Phillip LP
Sharma Yashoda Y
Silverberg Mark S MS
Simms Lisa A LA
Spain Sarah L SL
Sventoraityte Jurgita J
Targan Stephan R SR
Taylor Kent D KD
Theatre Emilie E
Tremelling Mark M
Vermeire Severine S
Verspaget Hein W HW
Weersma Rinse K RK
Wei Zhi Z
Wijmenga Cisca C
Wilson David C DC
Winkelmann Juliane J
Xavier Ramnik J RJ
Zeissig Sebastian S
Zhang Bin B
Zhao Hongyu H
JOURNAL
VOLUME: 45
ISSUE: 9
TITLE: Nature genetics
ISOABBREVIATION: Nat. Genet.
YEAR: 2013
MONTH: Sep
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Internet
ISSN: 1546-1718
ISSNTYPE: Electronic
MEDLINE JOURNAL
MEDLINETA: Nat Genet
COUNTRY: United States
ISSNLINKING: 1061-4036
NLMUNIQUEID: 9216904
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
COMMENTS AND CORRECTIONS
REFTYPE REFSOURCE REFPMID NOTE
Cites Arch Gen Psychiatry. 2003 May;60(5):497-502 12742871
Cites Bioinformatics. 2012 Oct 1;28(19):2540-2 22843982
Cites Am J Med Genet C Semin Med Genet. 2003 Nov 15;123C(1):48-58 14601036
Cites Ann Hum Genet. 1972 Nov;36(2):163-84 4676360
Cites Arch Gen Psychiatry. 1981 May;38(5):535-9 7235854
Cites Biol Psychiatry. 2005 Mar 15;57(6):655-60 15780853
Cites Schizophr Bull. 2006 Jan;32(1):9-16 16319375
Cites J Child Psychol Psychiatry. 2008 May;49(5):535-42 18221348
Cites Mol Psychiatry. 2009 Jan;14(1):71-85 17938636
Cites J Autism Dev Disord. 2009 Feb;39(2):197-209 18642069
Cites Lancet. 2009 Jan 17;373(9659):234-9 19150704
Cites J Am Acad Child Adolesc Psychiatry. 2009 Jan;48(1):10-8 19218893
Cites Arch Gen Psychiatry. 2009 Jul;66(7):748-55 19581566
Cites Nature. 2009 Aug 6;460(7256):748-52 19571811
Cites J Am Acad Child Adolesc Psychiatry. 2009 Nov;48(11):1094-101 19797986
Cites J Clin Psychiatry. 2009 Oct;70(10):1432-8 19538905
Cites Annu Rev Med. 2010;61:437-55 20059347
Cites Psychol Med. 2010 Feb;40(2):201-10 19607751
Cites Eur Child Adolesc Psychiatry. 2010 Mar;19(3):281-95 20148275
Cites Nat Genet. 2010 Jul;42(7):565-9 20562875
Cites J Am Acad Child Adolesc Psychiatry. 2010 Jul;49(7):675-85 20610137
Cites N Engl J Med. 2010 Jul 8;363(2):166-76 20647212
Cites J Am Acad Child Adolesc Psychiatry. 2010 Sep;49(9):884-97 20732625
Cites PLoS Genet. 2010 Sep;6(9):e1001097 20838587
Cites Mol Psychiatry. 2010 Oct;15(10):1016-22 19621016
Cites Am J Psychiatry. 2010 Nov;167(11):1357-63 20686188
Cites Am J Hum Genet. 2010 Nov 12;87(5):618-30 21055719
Cites Nat Genet. 2010 Dec;42(12):1118-25 21102463
Cites Am J Hum Genet. 2011 Jan 7;88(1):76-82 21167468
Cites Brain Res. 2011 Mar 22;1380:34-41 21078305
Cites Am J Hum Genet. 2011 Mar 11;88(3):294-305 21376301
Cites Nat Genet. 2011 Jun;43(6):519-25 21552263
Cites Am J Hum Genet. 2011 Jul 15;89(1):191-3; author reply 193-5 21763486
Cites Sci Transl Med. 2011 Aug 10;3(95):95ra75 21832240
Cites Am J Gastroenterol. 2011 Sep;106(9):1670-7 21537359
Cites Nat Genet. 2011 Oct;43(10):977-83 21926972
Cites Nat Genet. 2011 Oct;43(10):969-76 21926974
Cites Am J Med Genet B Neuropsychiatr Genet. 2011 Dec;156B(8):888-97 22012869
Cites Am J Psychiatry. 2011 Nov;168(11):1186-94 21676994
Cites Mol Psychiatry. 2012 Jan;17(1):36-48 21042317
Cites Am J Hum Genet. 2012 Jan 13;90(1):7-24 22243964
Cites MBio. 2012;3(1). pii: e00019-12. doi: 10.1128/mBio.00019-12 22334515
Cites Nat Genet. 2012 Mar;44(3):247-50 22344220
Cites Am J Psychiatry. 2012 Feb;169(2):186-94 22420046
Cites Am J Psychiatry. 2012 Feb;169(2):195-204 22420048
Cites PLoS One. 2012;7(4):e33224 22511918
Cites Eur J Hum Genet. 2012 Jun;20(6):668-74 22258521
Cites Hum Mol Genet. 2012 Nov 1;21(21):4781-92 22843504
Cites Am J Psychiatry. 2012 Dec;169(12):1256-66 23212057
Cites Proc Natl Acad Sci U S A. 2010 Jan 26;107 Suppl 1:1736-41 19955444
Cites Arch Gen Psychiatry. 2012 Nov;69(11):1099-1103 22752149
Cites Hum Mol Genet. 2013 Feb 15;22(4):832-41 23193196
Cites Mol Psychiatry. 2013 Apr;18(4):497-511 22472876
Cites Lancet. 2013 Apr 20;381(9875):1371-9 23453885
Cites BMJ. 2003 Sep 6;327(7414):557-60 12958120
Cites Genet Epidemiol. 2012 Apr;36(3):214-24 22714935
Cites Nat Rev Genet. 2012 Aug;13(8):537-51 22777127
Cites Biol Psychiatry. 2012 Oct 15;72(8):707-9 22520966
Cites Nat Genet. 2013 Oct;45(10):1150-9 23974872
GRANTS
GRANTID AGENCY COUNTRY
090532 Wellcome Trust United Kingdom
G0601030 Medical Research Council United Kingdom
G0701420 Medical Research Council United Kingdom
G0800675 Medical Research Council United Kingdom
G1000632 Medical Research Council United Kingdom
G1000718 Medical Research Council United Kingdom
G9810900 Medical Research Council United Kingdom
K05 AA017688 NIAAA NIH HHS United States
K99 MH101367 NIMH NIH HHS United States
P50 HD055782 NICHD NIH HHS United States
R01 CA082659 NCI NIH HHS United States
R01 MH041953 NIMH NIH HHS United States
R01 MH083094 NIMH NIH HHS United States
R01 MH094400 NIMH NIH HHS United States
R01 MH100027 NIMH NIH HHS United States
R01 MH100141 NIMH NIH HHS United States
R25 MH060482 NIMH NIH HHS United States
U01 MH085520 NIMH NIH HHS United States
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adult
Attention Deficit Disorder with Hyperactivity genetics
Bipolar Disorder genetics
Child genetics
Child Development Disorders, Pervasive genetics
Crohn Disease genetics
Depressive Disorder, Major genetics
Genetic Heterogeneity genetics
Genetic Predisposition to Disease genetics
Genome, Human genetics
Genome-Wide Association Study genetics
Humans genetics
Inheritance Patterns genetics
Mental Disorders genetics
Polymorphism, Single Nucleotide genetics
Schizophrenia genetics
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's
OTHERID SOURCE
NIHMS516146 NLM
PMC3800159 NLM