Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
23818653
TITLE
The nature and nurture of high IQ: an extended sensitive period for intellectual development.
ABSTRACT
IQ predicts many measures of life success, as well as trajectories of brain development. Prolonged cortical thickening observed in individuals with high IQ might reflect an extended period of synaptogenesis and high environmental sensitivity or plasticity. We tested this hypothesis by examining the timing of changes in the magnitude of genetic and environmental influences on IQ as a function of IQ score. We found that individuals with high IQ show high environmental influence on IQ into adolescence (resembling younger children), whereas individuals with low IQ show high heritability of IQ in adolescence (resembling adults), a pattern consistent with an extended sensitive period for intellectual development in more-intelligent individuals. The pattern held across a cross-sectional sample of almost 11,000 twin pairs and a longitudinal sample of twins, biological siblings, and adoptive siblings.
DATE PUBLISHED
2013 Aug
HISTORY
PUBSTATUS PUBSTATUSDATE
aheadofprint 2013/07/01
entrez 2013/07/03 06:00
pubmed 2013/07/03 06:00
medline 2014/05/03 06:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Brant AM Brant Angela M AM Department of Psychology, The Pennsylvania State University, PA 16802-3106, USA. amb76@psu.edu
Munakata Y Munakata Yuko Y
Boomsma DI Boomsma Dorret I DI
Defries JC Defries John C JC
Haworth CM Haworth Claire M A CM
Keller MC Keller Matthew C MC
Martin NG Martin Nicholas G NG
McGue M McGue Matthew M
Petrill SA Petrill Stephen A SA
Plomin R Plomin Robert R
Wadsworth SJ Wadsworth Sally J SJ
Wright MJ Wright Margaret J MJ
Hewitt JK Hewitt John K JK
INVESTIGATORS
JOURNAL
VOLUME: 24
ISSUE: 8
TITLE: Psychological science
ISOABBREVIATION: Psychol Sci
YEAR: 2013
MONTH: Aug
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Internet
ISSN: 1467-9280
ISSNTYPE: Electronic
MEDLINE JOURNAL
MEDLINETA: Psychol Sci
COUNTRY: United States
ISSNLINKING: 0956-7976
NLMUNIQUEID: 9007542
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Twin Study
COMMENTS AND CORRECTIONS
GRANTS
GRANTID AGENCY COUNTRY
HD010333 NICHD NIH HHS United States
MH079485 NIMH NIH HHS United States
R01 HD010333 NICHD NIH HHS United States
GENERAL NOTE
KEYWORDS
KEYWORD
behavior genetics
cognitive ability
cognitive development
individual differences
intelligence
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adolescent
Adolescent Development
Adult
Aged
Child
Child Development
Child, Preschool
Critical Period (Psychology)
Environment
Female
Gene-Environment Interaction
Humans
Intelligence genetics
Male genetics
Middle Aged genetics
Siblings genetics
Social Environment genetics
Twins genetics
Twins, Dizygotic genetics
Twins, Monozygotic genetics
Young Adult genetics
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's