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| PMID |
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| TITLE |
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| Leisure activity, health, and medical correlates of neurocognitive performance among monozygotic twins: the Older Australian Twins Study. |
|
| ABSTRACT |
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| OBJECTIVES |
NlmCategory: OBJECTIVE |
| We aimed to examine associations between each of three leisure activities (Cognitive, Physical, and Social) and performance in selected cognitive domains (Speed, Memory, Verbal ability, and Executive functions) and global cognition. We also aimed to explore associations between medical and health factors and late-life cognition. |
| METHOD |
NlmCategory: METHODS |
| Our sample comprised 119 pairs of monozygotic twins from the Older Australian Twins Study. Their mean age was 71 years and 66% were women. We used a discordant co-twin design, with cognitive performance measures as dependent variables and leisure activities as independent variables. Multiple regression analyses were performed, adjusting for potentially relevant medical and health factors. |
| RESULTS |
NlmCategory: RESULTS |
| Discordance in Cognitive Activity and Social Activity participation was positively associated with discordance in performance on some cognitive domains. There were no associations between Physical Activity participation and cognition. Discordance in several cardiovascular, frailty, and sensory variables was associated with discordance in cognitive performance measures. |
| DISCUSSION |
NlmCategory: CONCLUSIONS |
| This study identified lifestyle and health-related influences on late-life cognition. Our findings not only help in understanding the neurobiological mechanisms, they also have practical implications for interventions to prevent or slow age-related cognitive decline. |
| © The Author 2013. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. |
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| DATE PUBLISHED |
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| HISTORY |
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| PUBSTATUS |
PUBSTATUSDATE |
| aheadofprint |
2013/05/13 |
| entrez |
2013/05/15 06:00 |
| pubmed |
2013/05/15 06:00 |
| medline |
2014/08/13 06:00 |
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| AUTHORS |
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| NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
| Lee T |
|
Lee |
Teresa |
T |
|
Centre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, University of New South Wales, Randwick, Sydney, Australia. Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, Australia. teresa.lee@unsw.edu.au. |
| Lipnicki DM |
|
Lipnicki |
Darren M |
DM |
|
Centre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, University of New South Wales, Randwick, Sydney, Australia. |
| Crawford JD |
|
Crawford |
John D |
JD |
|
Centre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, University of New South Wales, Randwick, Sydney, Australia. |
| Henry JD |
|
Henry |
Julie D |
JD |
|
School of Psychology, University of Queensland, Brisbane, Australia. |
| Trollor JN |
|
Trollor |
Julian N |
JN |
|
Centre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, University of New South Wales, Randwick, Sydney, Australia. Department of Developmental Disability Neuropsychiatry, School of Psychiatry, Faculty of Medicine, University of New South Wales, Randwick, Sydney, Australia. |
| Ames D |
|
Ames |
David |
D |
|
National Ageing Research Institute, University of Melbourne, Victoria, Australia. University of Melbourne Academic Unit for Psychiatry of Old Age, St. George's Hospital, Melbourne, Australia. |
| Wright MJ |
|
Wright |
Margaret J |
MJ |
|
School of Psychology, University of Queensland, Brisbane, Australia. Genetic Epidemiology Unit, Queensland Institute of Medical Research, Brisbane, Australia. |
| Sachdev PS |
|
Sachdev |
Perminder S |
PS |
|
Centre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, University of New South Wales, Randwick, Sydney, Australia. Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, Australia. |
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OATS Research Team |
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| INVESTIGATORS |
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| JOURNAL |
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| VOLUME: 69 |
| ISSUE: 4 |
| TITLE: The journals of gerontology. Series B, Psychological sciences and social sciences |
| ISOABBREVIATION: J Gerontol B Psychol Sci Soc Sci |
| YEAR: 2014 |
| MONTH: Jul |
| DAY: |
| MEDLINEDATE: |
| SEASON: |
| CITEDMEDIUM: Internet |
| ISSN: 1758-5368 |
| ISSNTYPE: Electronic |
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| MEDLINE JOURNAL |
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| MEDLINETA: J Gerontol B Psychol Sci Soc Sci |
| COUNTRY: United States |
| ISSNLINKING: 1079-5014 |
| NLMUNIQUEID: 9508483 |
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| PUBLICATION TYPE |
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| PUBLICATIONTYPE TEXT |
| Journal Article |
| Research Support, Non-U.S. Gov't |
| Twin Study |
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| COMMENTS AND CORRECTIONS |
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| GRANTS |
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| GENERAL NOTE |
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| KEYWORDS |
|
| KEYWORD |
| Aging |
| Cognition |
| Health |
| Leisure activity |
| Twins. |
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| MESH HEADINGS |
|
| DESCRIPTORNAME |
QUALIFIERNAME |
| Aged |
|
| Aged, 80 and over |
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| Aging |
physiology |
| Australia |
epidemiology |
| Cognition |
physiology |
| Female |
physiology |
| Health Status |
physiology |
| Humans |
physiology |
| Leisure Activities |
physiology |
| Male |
physiology |
| Motor Activity |
physiology |
| Neuropsychological Tests |
physiology |
| Twins, Monozygotic |
statistics & numerical data |
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| SUPPLEMENTARY MESH |
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| GENE SYMBOLS |
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| CHEMICALS |
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| OTHER ID's |
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