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| PMID |
|
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| TITLE |
|
| Genotype by environment interactions in cognitive ability: a survey of 14 studies from four countries covering four age groups. |
|
| ABSTRACT |
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| A large part of the variation in cognitive ability is known to be due to genetic factors. Researchers have tried to identify modifiers that influence the heritability of cognitive ability, indicating a genotype by environment interaction (GĂ?E). To date, such modifiers include measured variables like income and socioeconomic status. The present paper focuses on GĂ?E in cognitive ability where the environmental variable is an unmeasured environmental factor that is uncorrelated in family members. We examined this type of GĂ?E in the GHCA-database (Haworth et al., Behav Genet 39:359-370, 2009), which comprises data of 14 different cognition studies from four different countries including participants of different ages. Results indicate that for younger participants (4-13 years), the strength of E decreases across the additive genetic factor A, but that this effect reverts for older participants (17-34 years). However, a clear and general conclusion about the presence of a genuine GĂ?E is hampered by differences between the individual studies with respect to environmental and genetic influences on cognitive ability. |
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| DATE PUBLISHED |
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| HISTORY |
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| PUBSTATUS |
PUBSTATUSDATE |
| received |
2012/08/30 |
| accepted |
2012/12/17 |
| aheadofprint |
2013/02/10 |
| entrez |
2013/02/12 06:00 |
| pubmed |
2013/02/12 06:00 |
| medline |
2013/11/20 06:00 |
|
| AUTHORS |
|
| NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
| Molenaar D |
|
Molenaar |
Dylan |
D |
|
Psychological Methods, Department of Psychology, University of Amsterdam, Weesperplein 4, 1018 XA, Amsterdam, The Netherlands. d.molenaar@uva.nl |
| van der Sluis S |
|
van der Sluis |
Sophie |
S |
|
|
| Boomsma DI |
|
Boomsma |
Dorret I |
DI |
|
|
| Haworth CM |
|
Haworth |
Claire M A |
CM |
|
|
| Hewitt JK |
|
Hewitt |
John K |
JK |
|
|
| Martin NG |
|
Martin |
Nicholas G |
NG |
|
|
| Plomin R |
|
Plomin |
Robert |
R |
|
|
| Wright MJ |
|
Wright |
Margaret J |
MJ |
|
|
| Dolan CV |
|
Dolan |
Conor V |
CV |
|
|
|
| INVESTIGATORS |
|
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| JOURNAL |
|
| VOLUME: 43 |
| ISSUE: 3 |
| TITLE: Behavior genetics |
| ISOABBREVIATION: Behav. Genet. |
| YEAR: 2013 |
| MONTH: May |
| DAY: |
| MEDLINEDATE: |
| SEASON: |
| CITEDMEDIUM: Internet |
| ISSN: 1573-3297 |
| ISSNTYPE: Electronic |
|
| MEDLINE JOURNAL |
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| MEDLINETA: Behav Genet |
| COUNTRY: United States |
| ISSNLINKING: 0001-8244 |
| NLMUNIQUEID: 0251711 |
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| PUBLICATION TYPE |
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| PUBLICATIONTYPE TEXT |
| Journal Article |
| Research Support, N.I.H., Extramural |
| Research Support, Non-U.S. Gov't |
| Twin Study |
|
| COMMENTS AND CORRECTIONS |
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| REFTYPE |
REFSOURCE |
REFPMID |
NOTE |
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| Cites |
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|
| GRANTS |
|
| GRANTID |
AGENCY |
COUNTRY |
| AA009367 |
NIAAA NIH HHS |
United States |
| DA011015 |
NIDA NIH HHS |
United States |
| G0500079 |
Medical Research Council |
United Kingdom |
| G0500079 |
Medical Research Council |
United Kingdom |
| G0500079(73692) |
Medical Research Council |
United Kingdom |
| HD027802 |
NICHD NIH HHS |
United States |
| HD038075 |
NICHD NIH HHS |
United States |
| HD044454 |
NICHD NIH HHS |
United States |
| HD046167 |
NICHD NIH HHS |
United States |
| HD11681 |
NICHD NIH HHS |
United States |
| P50 HD027802 |
NICHD NIH HHS |
United States |
| P60 DA011015 |
NIDA NIH HHS |
United States |
| R01 AA009367 |
NIAAA NIH HHS |
United States |
| R01 DA005147 |
NIDA NIH HHS |
United States |
| R01 DA013240 |
NIDA NIH HHS |
United States |
| R01 DA013240 |
NIDA NIH HHS |
United States |
| R01 HD010333 |
NICHD NIH HHS |
United States |
| R01 HD038075 |
NICHD NIH HHS |
United States |
| R01 HD044454 |
NICHD NIH HHS |
United States |
| R01 HD046167 |
NICHD NIH HHS |
United States |
| R37 DA005147 |
NIDA NIH HHS |
United States |
|
| GENERAL NOTE |
|
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| KEYWORDS |
|
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| MESH HEADINGS |
|
| DESCRIPTORNAME |
QUALIFIERNAME |
| Adolescent |
|
| Adult |
|
| Child |
|
| Child, Preschool |
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| Cognition |
|
| Female |
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| Gene-Environment Interaction |
|
| Genotype |
|
| Humans |
|
| Intelligence |
genetics |
| Intelligence Tests |
genetics |
| Male |
genetics |
| Models, Genetic |
genetics |
| Risk Factors |
genetics |
| Social Class |
genetics |
| Young Adult |
genetics |
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| SUPPLEMENTARY MESH |
|
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| GENE SYMBOLS |
|
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| CHEMICALS |
|
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| OTHER ID's |
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| OTHERID |
SOURCE |
| NIHMS561949 |
NLM |
| PMC4015869 |
NLM |
|
|
