Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
23187020
TITLE
The Brisbane Longitudinal Twin Study: Pathways to Cannabis Use, Abuse, and Dependence project-current status, preliminary results, and future directions.
ABSTRACT
We describe the data being collected from the Brisbane Longitudinal Twin Study in Australia as part of the US National Institute on Drug Abuse (NIDA)-funded project, Pathways to Cannabis Use, Abuse and Dependence. The history, recruitment, assessment, and retention of twin families in this project are described in detail, along with preliminary findings and plans for future research. The goal of this NIDA project is to make a significant contribution to the discovery of quantitative trait loci influencing cannabis use disorders. Although the focus is cannabis use, abuse, and dependence in young adults, measures of comorbid illicit drug use disorders are also being collected. In addition, a variety of internalizing and externalizing disorders are being assessed, funded by support from the Australian National Health and Medical Research Council. Because these same twins have participated in numerous twin studies since 1992, future plans will include linking different phenotypes to investigate relationships between drug use, psychiatric disorders, and psychological phenotypes within cross-sectional and longitudinal or developmental frameworks.
DATE PUBLISHED
2013 Feb
HISTORY
PUBSTATUS PUBSTATUSDATE
aheadofprint 2012/11/28
entrez 2012/11/29 06:00
pubmed 2012/11/29 06:00
medline 2013/06/19 06:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Gillespie NA Gillespie Nathan A NA Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA. ngillespie@vcu.edu
Henders AK Henders Anjali K AK
Davenport TA Davenport Tracy A TA
Hermens DF Hermens Daniel F DF
Wright MJ Wright Margie J MJ
Martin NG Martin Nicholas G NG
Hickie IB Hickie Ian B IB
INVESTIGATORS
JOURNAL
VOLUME: 16
ISSUE: 1
TITLE: Twin research and human genetics : the official journal of the International Society for Twin Studies
ISOABBREVIATION: Twin Res Hum Genet
YEAR: 2013
MONTH: Feb
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 1832-4274
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Twin Res Hum Genet
COUNTRY: England
ISSNLINKING: 1832-4274
NLMUNIQUEID: 101244624
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Comparative Study
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Twin Study
COMMENTS AND CORRECTIONS
REFTYPE REFSOURCE REFPMID NOTE
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GRANTS
GRANTID AGENCY COUNTRY
R00 DA023549 NIDA NIH HHS United States
R00DA023549 NIDA NIH HHS United States
R25 DA026119 NIDA NIH HHS United States
R37 DA018673 NIDA NIH HHS United States
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adolescent
Adult
Australia epidemiology
Cannabis chemistry
Child chemistry
Comorbidity chemistry
Diseases in Twins genetics
Female genetics
Humans genetics
Infant, Newborn genetics
Longitudinal Studies genetics
Male genetics
Marijuana Abuse genetics
National Institute on Drug Abuse (U.S.) genetics
Phenotype genetics
Pregnancy genetics
Risk Factors genetics
Substance-Related Disorders genetics
United States epidemiology
Young Adult epidemiology
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's
OTHERID SOURCE
NIHMS515967 NLM
PMC3805122 NLM