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PMID |
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TITLE |
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The Brisbane Longitudinal Twin Study: Pathways to Cannabis Use, Abuse, and Dependence project-current status, preliminary results, and future directions. |
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ABSTRACT |
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We describe the data being collected from the Brisbane Longitudinal Twin Study in Australia as part of the US National Institute on Drug Abuse (NIDA)-funded project, Pathways to Cannabis Use, Abuse and Dependence. The history, recruitment, assessment, and retention of twin families in this project are described in detail, along with preliminary findings and plans for future research. The goal of this NIDA project is to make a significant contribution to the discovery of quantitative trait loci influencing cannabis use disorders. Although the focus is cannabis use, abuse, and dependence in young adults, measures of comorbid illicit drug use disorders are also being collected. In addition, a variety of internalizing and externalizing disorders are being assessed, funded by support from the Australian National Health and Medical Research Council. Because these same twins have participated in numerous twin studies since 1992, future plans will include linking different phenotypes to investigate relationships between drug use, psychiatric disorders, and psychological phenotypes within cross-sectional and longitudinal or developmental frameworks. |
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DATE PUBLISHED |
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HISTORY |
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PUBSTATUS |
PUBSTATUSDATE |
aheadofprint |
2012/11/28 |
entrez |
2012/11/29 06:00 |
pubmed |
2012/11/29 06:00 |
medline |
2013/06/19 06:00 |
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AUTHORS |
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NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
Gillespie NA |
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Gillespie |
Nathan A |
NA |
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Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA. ngillespie@vcu.edu |
Henders AK |
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Henders |
Anjali K |
AK |
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Davenport TA |
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Davenport |
Tracy A |
TA |
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Hermens DF |
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Hermens |
Daniel F |
DF |
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Wright MJ |
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Wright |
Margie J |
MJ |
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Martin NG |
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Martin |
Nicholas G |
NG |
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Hickie IB |
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Hickie |
Ian B |
IB |
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INVESTIGATORS |
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JOURNAL |
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VOLUME: 16 |
ISSUE: 1 |
TITLE: Twin research and human genetics : the official journal of the International Society for Twin Studies |
ISOABBREVIATION: Twin Res Hum Genet |
YEAR: 2013 |
MONTH: Feb |
DAY: |
MEDLINEDATE: |
SEASON: |
CITEDMEDIUM: Print |
ISSN: 1832-4274 |
ISSNTYPE: Print |
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MEDLINE JOURNAL |
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MEDLINETA: Twin Res Hum Genet |
COUNTRY: England |
ISSNLINKING: 1832-4274 |
NLMUNIQUEID: 101244624 |
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PUBLICATION TYPE |
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PUBLICATIONTYPE TEXT |
Comparative Study |
Journal Article |
Research Support, N.I.H., Extramural |
Research Support, Non-U.S. Gov't |
Twin Study |
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COMMENTS AND CORRECTIONS |
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REFTYPE |
REFSOURCE |
REFPMID |
NOTE |
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GRANTS |
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GRANTID |
AGENCY |
COUNTRY |
R00 DA023549 |
NIDA NIH HHS |
United States |
R00DA023549 |
NIDA NIH HHS |
United States |
R25 DA026119 |
NIDA NIH HHS |
United States |
R37 DA018673 |
NIDA NIH HHS |
United States |
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GENERAL NOTE |
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KEYWORDS |
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MESH HEADINGS |
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DESCRIPTORNAME |
QUALIFIERNAME |
Adolescent |
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Adult |
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Australia |
epidemiology |
Cannabis |
chemistry |
Child |
chemistry |
Comorbidity |
chemistry |
Diseases in Twins |
genetics |
Female |
genetics |
Humans |
genetics |
Infant, Newborn |
genetics |
Longitudinal Studies |
genetics |
Male |
genetics |
Marijuana Abuse |
genetics |
National Institute on Drug Abuse (U.S.) |
genetics |
Phenotype |
genetics |
Pregnancy |
genetics |
Risk Factors |
genetics |
Substance-Related Disorders |
genetics |
United States |
epidemiology |
Young Adult |
epidemiology |
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SUPPLEMENTARY MESH |
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GENE SYMBOLS |
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CHEMICALS |
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OTHER ID's |
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OTHERID |
SOURCE |
NIHMS515967 |
NLM |
PMC3805122 |
NLM |
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