Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
2314570
TITLE
Covert orientation of visual attention in Parkinson's disease: an impairment in the maintenance of attention.
ABSTRACT
Covert orientation of attention was studied in a group of patients with idiopathic Parkinson's disease and compared to a matched control group using a cued reaction time task which measured disengagement, covert movement and engagement of attention. Parkinson patients had an increased response latency and disengaged from attended locations more readily than controls. This impairment in the maintenance of attention in Parkinson's disease was comparable to that produced in a previous study by pharmacological blockade of brain catecholamines in normal subjects. It is suggested that an impairment in the maintenance of oriented attention may underlie some of the cognitive deficits reported in Parkinson's disease.
DATE PUBLISHED
1990
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 1990/01/01
medline 1990/01/01 00:01
entrez 1990/01/01 00:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Wright MJ Wright M J MJ Department of Physiology, Flinders University of South Australia, Bedford Park.
Burns RJ Burns R J RJ
Geffen GM Geffen G M GM
Geffen LB Geffen L B LB
INVESTIGATORS
JOURNAL
VOLUME: 28
ISSUE: 2
TITLE: Neuropsychologia
ISOABBREVIATION: Neuropsychologia
YEAR: 1990
MONTH:
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0028-3932
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Neuropsychologia
COUNTRY: England
ISSNLINKING: 0028-3932
NLMUNIQUEID: 0020713
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, Non-U.S. Gov't
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Aged
Attention
Fatigue psychology
Female psychology
Form Perception psychology
Humans psychology
Male psychology
Middle Aged psychology
Orientation psychology
Parkinson Disease psychology
Pattern Recognition, Visual psychology
Psychomotor Performance psychology
Reaction Time psychology
Visual Fields psychology
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's