Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
2308068
TITLE
Psychoticism as a dimension of personality: a multivariate genetic test of Eysenck and Eysenck's psychoticism construct.
ABSTRACT
In this study, we applied multivariate genetic analysis, a generalization of factor analysis and behavior genetic analysis, to responses to items of the Psychoticism scale of the Eysenck Personality Questionnaire by 2,903 adult same-sex Australian twin pairs. Item loadings on genetic, shared environmental, and nonshared environmental common and specific factors were estimated. The genetic factor structure differed considerably from the environmental structures, particularly in men. The genetic correlation between suspiciousness items and items reflecting unconventional or tough-minded attitudes or hostility to others was negative, but the environmental correlation was positive. Thus, conventional behavior genetic studies that have reported significant heritability of psychoticism, on the basis of analyses of scale scores, are misleading as to what trait is being inherited.
DATE PUBLISHED
1990 Jan
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 1990/01/01
medline 1990/01/01 00:01
entrez 1990/01/01 00:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Heath AC Heath A C AC Department of Human Genetics, Medical College of Virginia.
Martin NG Martin N G NG
INVESTIGATORS
JOURNAL
VOLUME: 58
ISSUE: 1
TITLE: Journal of personality and social psychology
ISOABBREVIATION: J Pers Soc Psychol
YEAR: 1990
MONTH: Jan
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0022-3514
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: J Pers Soc Psychol
COUNTRY: United States
ISSNLINKING: 0022-3514
NLMUNIQUEID: 0014171
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
COMMENTS AND CORRECTIONS
GRANTS
GRANTID AGENCY COUNTRY
AA06781 NIAAA NIH HHS United States
AG04954 NIA NIH HHS United States
GM30250 NIGMS NIH HHS United States
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adult
Diseases in Twins psychology
Humans psychology
Models, Genetic psychology
Personality Tests psychology
Phenotype psychology
Psychometrics psychology
Psychotic Disorders psychology
Risk Factors psychology
Social Environment psychology
Twins, Dizygotic genetics
Twins, Monozygotic genetics
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's