PMID |
|
|
TITLE |
|
Offspring ADHD as a risk factor for parental marital problems: controls for genetic and environmental confounds. |
|
ABSTRACT |
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BACKGROUND |
NlmCategory: BACKGROUND |
Previous studies have found that child attention-deficit/hyperactivity disorder (ADHD) is associated with more parental marital problems. However, the reasons for this association are unclear. The association might be due to genetic or environmental confounds that contribute to both marital problems and ADHD. |
METHOD |
NlmCategory: METHODS |
Data were drawn from the Australian Twin Registry, including 1,296 individual twins, their spouses, and offspring. We studied adult twins who were discordant for offspring ADHD.Using a discordant twin pairs design, we examined the extent to which genetic and environmental confounds,as well as measured parental and offspring characteristics, explain the ADHD-marital problems association. |
RESULTS |
NlmCategory: RESULTS |
Offspring ADHD predicted parental divorce and marital conflict. The associations were also robust when comparing differentially exposed identical twins to control for unmeasured genetic and environmental factors, when controlling for measured maternal and paternal psychopathology,when restricting the sample based on timing of parental divorce and ADHD onset, and when controlling for other forms of offspring psychopathology. Each of these controls rules out alternative explanations for the association. |
CONCLUSION |
NlmCategory: CONCLUSIONS |
The results of the current study converge with those of prior research in suggesting that factors directly associated with offspring ADHD increase parental marital problems. |
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DATE PUBLISHED |
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HISTORY |
|
PUBSTATUS |
PUBSTATUSDATE |
aheadofprint |
2012/09/10 |
entrez |
2012/09/11 06:00 |
pubmed |
2012/09/11 06:00 |
medline |
2013/02/16 06:00 |
|
AUTHORS |
|
NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
Schermerhorn AC |
|
Schermerhorn |
Alice C |
AC |
|
Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, USA. |
D'Onofrio BM |
|
D'Onofrio |
Brian M |
BM |
|
|
Slutske WS |
|
Slutske |
Wendy S |
WS |
|
|
Emery RE |
|
Emery |
Robert E |
RE |
|
|
Turkheimer E |
|
Turkheimer |
Eric |
E |
|
|
Harden KP |
|
Harden |
K Paige |
KP |
|
|
Heath AC |
|
Heath |
Andrew C |
AC |
|
|
Martin NG |
|
Martin |
Nicholas G |
NG |
|
|
|
INVESTIGATORS |
|
|
JOURNAL |
|
VOLUME: 15 |
ISSUE: 6 |
TITLE: Twin research and human genetics : the official journal of the International Society for Twin Studies |
ISOABBREVIATION: Twin Res Hum Genet |
YEAR: 2012 |
MONTH: Dec |
DAY: |
MEDLINEDATE: |
SEASON: |
CITEDMEDIUM: Print |
ISSN: |
ISSNTYPE: |
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MEDLINE JOURNAL |
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MEDLINETA: Twin Res Hum Genet |
COUNTRY: England |
ISSNLINKING: 1832-4274 |
NLMUNIQUEID: 101244624 |
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PUBLICATION TYPE |
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PUBLICATIONTYPE TEXT |
Clinical Trial |
Journal Article |
Multicenter Study |
Research Support, N.I.H., Extramural |
Twin Study |
|
COMMENTS AND CORRECTIONS |
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REFTYPE |
REFSOURCE |
REFPMID |
NOTE |
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|
|
GRANTS |
|
GRANTID |
AGENCY |
COUNTRY |
AA000264 |
NIAAA NIH HHS |
United States |
AA07535 |
NIAAA NIH HHS |
United States |
HD053550 |
NICHD NIH HHS |
United States |
HD056354 |
NICHD NIH HHS |
United States |
HD064795 |
NICHD NIH HHS |
United States |
K05 AA017688 |
NIAAA NIH HHS |
United States |
R01 HD061817 |
NICHD NIH HHS |
United States |
T32HD007475 |
NICHD NIH HHS |
United States |
|
GENERAL NOTE |
|
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KEYWORDS |
|
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MESH HEADINGS |
|
DESCRIPTORNAME |
QUALIFIERNAME |
Adult |
|
Aged |
|
Attention Deficit Disorder with Hyperactivity |
psychology |
Australia |
psychology |
Divorce |
psychology |
Female |
psychology |
Follow-Up Studies |
psychology |
Gene-Environment Interaction |
psychology |
Humans |
psychology |
Male |
psychology |
Middle Aged |
psychology |
Retrospective Studies |
psychology |
|
SUPPLEMENTARY MESH |
|
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GENE SYMBOLS |
|
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CHEMICALS |
|
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OTHER ID's |
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OTHERID |
SOURCE |
NIHMS463776 |
NLM |
PMC3678725 |
NLM |
|