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PMID |
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TITLE |
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Evidence for genetic influences on sleep disturbance and sleep pattern in twins. |
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ABSTRACT |
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The etiologic role of genotype and environment in sleep pattern (daytime napping, habitual bedtime, and sleep duration) and subjective sleep quality and sleep disturbance was examined using a general population sample of 3,810 adult Australian twin pairs, aged 17-88 years. Genetic differences accounted for at least 33% of the variance in sleep quality and sleep disturbance and 40% of the variance in sleep pattern. There was no evidence for a decline in the importance of genetic predisposition with age. Short-term environmental fluctuations accounted for as much as 30% of the variance, and more stable nonfamilial environmental effects accounted for the remainder. No effect of shared family environment on sleep characteristics was found. |
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DATE PUBLISHED |
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HISTORY |
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PUBSTATUS |
PUBSTATUSDATE |
pubmed |
1990/08/01 |
medline |
1990/08/01 00:01 |
entrez |
1990/08/01 00:00 |
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AUTHORS |
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NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
Heath AC |
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Heath |
A C |
AC |
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Department of Human Genetics, Medical College of Virginia, Richmond. |
Kendler KS |
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Kendler |
K S |
KS |
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Eaves LJ |
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Eaves |
L J |
LJ |
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Martin NG |
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Martin |
N G |
NG |
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INVESTIGATORS |
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JOURNAL |
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VOLUME: 13 |
ISSUE: 4 |
TITLE: Sleep |
ISOABBREVIATION: Sleep |
YEAR: 1990 |
MONTH: Aug |
DAY: |
MEDLINEDATE: |
SEASON: |
CITEDMEDIUM: Print |
ISSN: |
ISSNTYPE: |
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MEDLINE JOURNAL |
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MEDLINETA: Sleep |
COUNTRY: United States |
ISSNLINKING: 0161-8105 |
NLMUNIQUEID: 7809084 |
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PUBLICATION TYPE |
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PUBLICATIONTYPE TEXT |
Journal Article |
Research Support, Non-U.S. Gov't |
Research Support, U.S. Gov't, P.H.S. |
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COMMENTS AND CORRECTIONS |
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GRANTS |
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GRANTID |
AGENCY |
COUNTRY |
AA06782 |
NIAAA NIH HHS |
United States |
AA07728 |
NIAAA NIH HHS |
United States |
DA05588 |
NIDA NIH HHS |
United States |
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GENERAL NOTE |
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KEYWORDS |
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MESH HEADINGS |
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DESCRIPTORNAME |
QUALIFIERNAME |
Adult |
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Aged |
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Aged, 80 and over |
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Anxiety Disorders |
psychology |
Cohort Studies |
psychology |
Diseases in Twins |
psychology |
Female |
psychology |
Humans |
psychology |
Male |
psychology |
Middle Aged |
psychology |
Models, Genetic |
psychology |
Risk Factors |
psychology |
Sleep Disorders |
psychology |
Sleep Initiation and Maintenance Disorders |
psychology |
Twins, Dizygotic |
genetics |
Twins, Monozygotic |
genetics |
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SUPPLEMENTARY MESH |
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GENE SYMBOLS |
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CHEMICALS |
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OTHER ID's |
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