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PMID |
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TITLE |
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Estimating heritability from twin studies. |
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ABSTRACT |
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This chapter describes how the heritability of a trait can be estimated using data collected from pairs of twins. The principles of the classical twin design are described, followed by the assumptions and possible extensions of the design. In the second part of this chapter, two example scripts are presented and described, explaining the basic steps for estimating heritability using the statistical program OpenMx. OpenMx and the scripts used for this chapter can be downloaded so that readers can adapt and use the scripts for their own purposes. |
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DATE PUBLISHED |
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HISTORY |
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PUBSTATUS |
PUBSTATUSDATE |
entrez |
2012/02/07 06:00 |
pubmed |
2012/02/07 06:00 |
medline |
2012/05/12 06:00 |
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AUTHORS |
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NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
Verweij KJ |
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Verweij |
Karin J H |
KJ |
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Genetic Epidemiology Unit, Queensland Institute of Medical Research, Brisbane, QLD, Australia. |
Mosing MA |
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Mosing |
Miriam A |
MA |
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Zietsch BP |
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Zietsch |
Brendan P |
BP |
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Medland SE |
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Medland |
Sarah E |
SE |
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INVESTIGATORS |
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JOURNAL |
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VOLUME: 850 |
ISSUE: |
TITLE: Methods in molecular biology (Clifton, N.J.) |
ISOABBREVIATION: Methods Mol Biol |
YEAR: 2012 |
MONTH: |
DAY: |
MEDLINEDATE: |
SEASON: |
CITEDMEDIUM: Internet |
ISSN: 1940-6029 |
ISSNTYPE: Electronic |
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MEDLINE JOURNAL |
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MEDLINETA: Methods Mol Biol |
COUNTRY: United States |
ISSNLINKING: 1064-3745 |
NLMUNIQUEID: 9214969 |
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PUBLICATION TYPE |
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PUBLICATIONTYPE TEXT |
Journal Article |
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COMMENTS AND CORRECTIONS |
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GRANTS |
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GENERAL NOTE |
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KEYWORDS |
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MESH HEADINGS |
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DESCRIPTORNAME |
QUALIFIERNAME |
Female |
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Humans |
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Male |
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Models, Genetic |
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Twin Studies as Topic |
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Twins |
genetics |
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SUPPLEMENTARY MESH |
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GENE SYMBOLS |
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CHEMICALS |
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OTHER ID's |
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