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| PMID |
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| TITLE |
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| Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer. |
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| ABSTRACT |
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| DATE PUBLISHED |
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| HISTORY |
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| PUBSTATUS |
PUBSTATUSDATE |
| received |
2011/03/05 |
| accepted |
2011/04/08 |
| epublish |
2011/06/02 |
| entrez |
2011/06/10 06:00 |
| pubmed |
2011/06/10 06:00 |
| medline |
2011/09/29 06:00 |
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| AUTHORS |
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| NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
| Tomlinson IP |
|
Tomlinson |
Ian P M |
IP |
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom. |
|
| Carvajal-Carmona LG |
|
Carvajal-Carmona |
Luis G |
LG |
|
|
| Dobbins SE |
|
Dobbins |
Sara E |
SE |
|
|
| Tenesa A |
|
Tenesa |
Albert |
A |
|
|
| Jones AM |
|
Jones |
Angela M |
AM |
|
|
| Howarth K |
|
Howarth |
Kimberley |
K |
|
|
| Palles C |
|
Palles |
Claire |
C |
|
|
| Broderick P |
|
Broderick |
Peter |
P |
|
|
| Jaeger EE |
|
Jaeger |
Emma E M |
EE |
|
|
| Farrington S |
|
Farrington |
Susan |
S |
|
|
| Lewis A |
|
Lewis |
Annabelle |
A |
|
|
| Prendergast JG |
|
Prendergast |
James G D |
JG |
|
|
| Pittman AM |
|
Pittman |
Alan M |
AM |
|
|
| Theodoratou E |
|
Theodoratou |
Evropi |
E |
|
|
| Olver B |
|
Olver |
Bianca |
B |
|
|
| Walker M |
|
Walker |
Marion |
M |
|
|
| Penegar S |
|
Penegar |
Steven |
S |
|
|
| Barclay E |
|
Barclay |
Ella |
E |
|
|
| Whiffin N |
|
Whiffin |
Nicola |
N |
|
|
| Martin L |
|
Martin |
Lynn |
L |
|
|
| Ballereau S |
|
Ballereau |
Stephane |
S |
|
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| Lloyd A |
|
Lloyd |
Amy |
A |
|
|
| Gorman M |
|
Gorman |
Maggie |
M |
|
|
| Lubbe S |
|
Lubbe |
Steven |
S |
|
|
|
COGENT Consortium |
|
|
|
|
|
|
CORGI Collaborators |
|
|
|
|
|
|
EPICOLON Consortium |
|
|
|
|
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| Howie B |
|
Howie |
Bryan |
B |
|
|
| Marchini J |
|
Marchini |
Jonathan |
J |
|
|
| Ruiz-Ponte C |
|
Ruiz-Ponte |
Clara |
C |
|
|
| Fernandez-Rozadilla C |
|
Fernandez-Rozadilla |
Ceres |
C |
|
|
| Castells A |
|
Castells |
Antoni |
A |
|
|
| Carracedo A |
|
Carracedo |
Angel |
A |
|
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| Castellvi-Bel S |
|
Castellvi-Bel |
Sergi |
S |
|
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| Duggan D |
|
Duggan |
David |
D |
|
|
| Conti D |
|
Conti |
David |
D |
|
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| Cazier JB |
|
Cazier |
Jean-Baptiste |
JB |
|
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| Campbell H |
|
Campbell |
Harry |
H |
|
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| Sieber O |
|
Sieber |
Oliver |
O |
|
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| Lipton L |
|
Lipton |
Lara |
L |
|
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| Gibbs P |
|
Gibbs |
Peter |
P |
|
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| Martin NG |
|
Martin |
Nicholas G |
NG |
|
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| Montgomery GW |
|
Montgomery |
Grant W |
GW |
|
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| Young J |
|
Young |
Joanne |
J |
|
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| Baird PN |
|
Baird |
Paul N |
PN |
|
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| Gallinger S |
|
Gallinger |
Steven |
S |
|
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| Newcomb P |
|
Newcomb |
Polly |
P |
|
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| Hopper J |
|
Hopper |
John |
J |
|
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| Jenkins MA |
|
Jenkins |
Mark A |
MA |
|
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| Aaltonen LA |
|
Aaltonen |
Lauri A |
LA |
|
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| Kerr DJ |
|
Kerr |
David J |
DJ |
|
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| Cheadle J |
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Cheadle |
Jeremy |
J |
|
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| Pharoah P |
|
Pharoah |
Paul |
P |
|
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| Casey G |
|
Casey |
Graham |
G |
|
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| Houlston RS |
|
Houlston |
Richard S |
RS |
|
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| Dunlop MG |
|
Dunlop |
Malcolm G |
MG |
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| INVESTIGATORS |
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| JOURNAL |
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| MEDLINE JOURNAL |
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| MEDLINETA: PLoS Genet |
| COUNTRY: United States |
| ISSNLINKING: 1553-7390 |
| NLMUNIQUEID: 101239074 |
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| PUBLICATION TYPE |
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| PUBLICATIONTYPE TEXT |
| Journal Article |
| Research Support, N.I.H., Extramural |
| Research Support, Non-U.S. Gov't |
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| COMMENTS AND CORRECTIONS |
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| REFTYPE |
REFSOURCE |
REFPMID |
NOTE |
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| Cites |
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Int J Cancer. 2011 May 1;128(9):2075-84 |
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20837956 |
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Am J Hum Genet. 2010 Jul 9;87(1):6-16 |
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PLoS Biol. 2010 Jan;8(1):e1000294 |
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Nat Genet. 2009 Oct;41(10):1058-60 |
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19011631 |
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18699762 |
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Nat Genet. 2008 Jan;40(1):26-8 |
18084292 |
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Cancer Epidemiol Biomarkers Prev. 2007 Nov;16(11):2331-43 |
17982118 |
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Nat Genet. 2007 Nov;39(11):1315-7 |
17934461 |
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17618284 |
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J Pediatr. 2006 Jan;148(1):54-61 |
16423598 |
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| Cites |
Science. 1998 May 15;280(5366):1086-8 |
9582123 |
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QJM. 1996 Oct;89(10):737-43 |
8944229 |
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| Cites |
Ann Epidemiol. 1994 Mar;4(2):115-8 |
8205277 |
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Am J Hum Genet. 2003 May;72(5):1261-7 |
12696020 |
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| Cites |
Stat Med. 2002 Jun 15;21(11):1539-58 |
12111919 |
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| Cites |
PLoS Biol. 2011;9(1):e1000579 |
21267061 |
|
| Cites |
Gastroenterology. 2010 Sep;139(3):788-96, 796.e1-6 |
20638935 |
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| GRANTS |
|
| GRANTID |
AGENCY |
COUNTRY |
| 075491/Z/04 |
Wellcome Trust |
United Kingdom |
| 090532 |
Wellcome Trust |
United Kingdom |
| 12076 |
Cancer Research UK |
United Kingdom |
| A10119 |
Cancer Research UK |
United Kingdom |
| A10124 |
Cancer Research UK |
United Kingdom |
| C31250/A10107 |
Cancer Research UK |
United Kingdom |
| CA-95-011 |
NCI NIH HHS |
United States |
| CZB/4/449 |
Chief Scientist Office |
United Kingdom |
| G0000657-53203 |
Medical Research Council |
United Kingdom |
| G0301096 |
Medical Research Council |
United Kingdom |
| MC_U127527198 |
Medical Research Council |
United Kingdom |
| MR/K001744/1 |
Medical Research Council |
United Kingdom |
| UO1 CA074783 |
NCI NIH HHS |
United States |
| UO1 CA074794 |
NCI NIH HHS |
United States |
| UO1 CA074799 |
NCI NIH HHS |
United States |
| UO1 CA074800 |
NCI NIH HHS |
United States |
| UO1 CA074806 |
NCI NIH HHS |
United States |
| UO1 CA097735 |
NCI NIH HHS |
United States |
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| GENERAL NOTE |
|
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| KEYWORDS |
|
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| MESH HEADINGS |
|
| DESCRIPTORNAME |
QUALIFIERNAME |
| Aged |
|
| Bone Morphogenetic Protein 2 |
metabolism |
| Bone Morphogenetic Protein 4 |
metabolism |
| Case-Control Studies |
metabolism |
| Colorectal Neoplasms |
metabolism |
| Gene Frequency |
metabolism |
| Genetic Predisposition to Disease |
metabolism |
| Genetic Variation |
metabolism |
| Genome-Wide Association Study |
metabolism |
| Humans |
metabolism |
| Intercellular Signaling Peptides and Proteins |
genetics |
| Male |
genetics |
| Middle Aged |
genetics |
| Polymorphism, Single Nucleotide |
genetics |
| Quantitative Trait, Heritable |
genetics |
| Signal Transduction |
genetics |
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| SUPPLEMENTARY MESH |
|
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| GENE SYMBOLS |
|
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| CHEMICALS |
|
| REGISTRYNUMBER |
NAMEOFSUBSTANCE |
| 0 |
BMP2 protein, human |
| 0 |
BMP4 protein, human |
| 0 |
Bone Morphogenetic Protein 2 |
| 0 |
Bone Morphogenetic Protein 4 |
| 0 |
GREM1 protein, human |
| 0 |
Intercellular Signaling Peptides and Proteins |
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| OTHER ID's |
|
| OTHERID |
SOURCE |
| PMC3107194 |
NLM |
|
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