Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
QIMR Home Page
GenEpi Home Page
Publications
Contacts
Research
Staff Index
Collaborators
Software Tools
Computing Resources
Studies
Search
GenEpi Intranet
PMID
21244438
TITLE
Alcoholic marriage: later start, sooner end.
ABSTRACT
BACKGROUND NlmCategory: BACKGROUND
Although associations between drinking behavior and marital status are well documented, timing of marital transitions as a function of alcohol use or disorder has received limited empirical attention.
METHODS NlmCategory: METHODS
We examine the relationship between lifetime history of alcohol dependence (AD) and timing and survival of first marriages in a sample of 3,575 female and 1,845 male adult Australian twins born mostly between 1940 and 1964. Survival analyses were conducted using Cox proportional hazards regression models.
RESULTS NlmCategory: RESULTS
Results indicate moderate delays in marriage associated with AD for both women and men. Among ever-married respondents, AD was strongly predictive of early separation, with similar effects observed for women and men. Heritable sources of covariation were also documented. For women, genetic influences shared between early-onset AD and marital timing were found. Genetic influences shared between AD and marital survival were observed for women without regard to onset and for men with later-onset AD.
CONCLUSIONS NlmCategory: CONCLUSIONS
Results confirm the importance of AD as a predictor of both timing and survival of first marriages, with genetic influences contributing to observed associations.
Copyright 2011 by the Research Society on Alcoholism.
DATE PUBLISHED
2011 Apr
HISTORY
PUBSTATUS PUBSTATUSDATE
aheadofprint 2011/01/18
entrez 2011/01/20 06:00
pubmed 2011/01/20 06:00
medline 2011/12/14 06:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Waldron M Waldron Mary M Department of Counseling and Educational Psychology, School of Education, Indiana University, 201 N. Rose Avenue, Bloomington, IN 47405, USA. mwaldron@indiana.edu
Heath AC Heath Andrew C AC
Lynskey MT Lynskey Michael T MT
Bucholz KK Bucholz Kathleen K KK
Madden PA Madden Pamela A F PA
Martin NG Martin Nicholas G NG
INVESTIGATORS
JOURNAL
VOLUME: 35
ISSUE: 4
TITLE: Alcoholism, clinical and experimental research
ISOABBREVIATION: Alcohol. Clin. Exp. Res.
YEAR: 2011
MONTH: Apr
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Internet
ISSN: 1530-0277
ISSNTYPE: Electronic
MEDLINE JOURNAL
MEDLINETA: Alcohol Clin Exp Res
COUNTRY: England
ISSNLINKING: 0145-6008
NLMUNIQUEID: 7707242
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, N.I.H., Extramural
Twin Study
COMMENTS AND CORRECTIONS
REFTYPE REFSOURCE REFPMID NOTE
Cites Arch Gen Psychiatry. 2000 Aug;57(8):803-11 10920470
Cites J Stud Alcohol Drugs. 2009 Sep;70(5):786-96 19737504
Cites Twin Res. 2001 Apr;4(2):73-80 11665339
Cites J Stud Alcohol. 2001 Sep;62(5):589-604 11702798
Cites J Abnorm Psychol. 2002 Feb;111(1):124-33 11871377
Cites Arch Gen Psychiatry. 2002 Dec;59(12):1125-32 12470129
Cites Alcohol Res Health. 2002;26(4):274-81 12875037
Cites Clin Psychol Rev. 2003 Dec;23(7):959-97 14624823
Cites J Pers Soc Psychol. 2004 Feb;86(2):285-94 14769084
Cites Acta Genet Stat Med. 1966;16(3):265-75 4959152
Cites Addiction. 1999 Sep;94(9):1361-70 10615721
Cites J Biosoc Sci. 2000 Jan;32(1):63-88 10676060
Cites Addiction. 1999 Oct;94(10):1477-87 10790900
Cites Demography. 1977 Aug;14(3):265-72 892110
Cites Ann Hum Genet. 1975 Oct;39(2):219-29 1053249
Cites Am J Public Health. 1984 Nov;74(11):1231-8 6496815
Cites Acta Genet Med Gemellol (Roma). 1984;33(3):435-50 6543278
Cites Behav Genet. 1985 Jul;15(4):305-47 4041178
Cites J Drug Educ. 1985;15(3):253-61 4078654
Cites Behav Genet. 1985 Mar;15(2):93-109 3838073
Cites Br J Addict. 1990 Apr;85(4):521-30 2346791
Cites Acta Genet Med Gemellol (Roma). 1990;39(1):109-15 2392887
Cites Am J Public Health. 1991 Mar;81(3):305-18 1994739
Cites J Stud Alcohol. 1991 Sep;52(5):434-40 1943098
Cites Br J Addict. 1991 Oct;86(10):1269-81 1836409
Cites J Health Soc Behav. 1992 Dec;33(4):328-47 1464718
Cites J Subst Abuse. 1993;5(1):1-14 8329877
Cites Arch Gen Psychiatry. 1994 Jan;51(1):8-19 8279933
Cites Am J Psychiatry. 1994 May;151(5):707-15 8166312
Cites J Stud Alcohol. 1994 Mar;55(2):149-58 8189735
Cites J Subst Abuse. 1994;6(2):209-17 7804019
Cites J Health Soc Behav. 1996 Jun;37(2):121-32 8690874
Cites J Pers Soc Psychol. 1996 Aug;71(2):288-99 8765483
Cites Demography. 1995 Nov;32(4):483-507 8925942
Cites J Health Soc Behav. 1996 Dec;37(4):339-49 8997889
Cites J Stud Alcohol. 1997 Sep;58(5):464-73 9273910
Cites Psychol Med. 1997 Nov;27(6):1381-96 9403910
Cites J Subst Abuse. 1997;9:103-10 9494942
Cites Am J Psychiatry. 1998 Aug;155(8):1092-6 9699699
Cites J Stud Alcohol. 1998 Nov;59(6):647-58 9811086
Cites J Stud Alcohol. 1998 Nov;59(6):659-68 9811087
Cites Addiction. 1998 Nov;93(11):1717-27 9926534
Cites J Stud Alcohol Suppl. 1999 Mar;13:139-46 10225498
Cites J Stud Alcohol. 1999 May;60(3):368-77 10371265
Cites J Stud Alcohol. 1999 Sep;60(5):647-52 10487734
Cites Psychol Addict Behav. 2004 Dec;18(4):340-9 15631606
Cites Alcohol Res Health. 2000;24(4):209-14 15986715
Cites Soc Sci Med. 2005 Dec;61(11):2304-16 16139939
Cites Behav Genet. 2006 Jul;36(4):553-66 16710775
Cites Psychol Med. 2006 Oct;36(10):1461-71 16734942
Cites J Consult Clin Psychol. 2007 Feb;75(1):43-51 17295562
Cites Behav Genet. 2007 Mar;37(2):362-75 17165140
Cites Alcohol Clin Exp Res. 2007 May;31(5):717-28 17378921
Cites Addiction. 2007 May;102(5):786-94 17493107
Cites Arch Gen Psychiatry. 2007 Jul;64(7):830-42 17606817
Cites J Abnorm Psychol. 2007 Aug;116(3):638-43 17696721
Cites Annu Rev Clin Psychol. 2007;3:285-310 17716057
Cites Psychosom Med. 2008 May;70(4):482-7 18480194
Cites Alcohol Clin Exp Res. 2008 Nov;32(11):1865-74 18778383
Cites J Subst Abuse. 2000;11(3):253-63 11026124
GRANTS
GRANTID AGENCY COUNTRY
AA07728 NIAAA NIH HHS United States
AA11998 NIAAA NIH HHS United States
AA15210 NIAAA NIH HHS United States
AA17688 NIAAA NIH HHS United States
DA023696 NIDA NIH HHS United States
HD52543 NICHD NIH HHS United States
K01 DA023696 NIDA NIH HHS United States
K01 DA023696-03 NIDA NIH HHS United States
K05 AA017688 NIAAA NIH HHS United States
K05 AA017688-03 NIAAA NIH HHS United States
P60 AA011998 NIAAA NIH HHS United States
P60 AA011998-13 NIAAA NIH HHS United States
R01 AA015210 NIAAA NIH HHS United States
R01 AA015210-05 NIAAA NIH HHS United States
R37 AA007728 NIAAA NIH HHS United States
R37 AA007728-20 NIAAA NIH HHS United States
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adult
Aged
Aged, 80 and over
Alcohol Drinking psychology
Alcoholism psychology
Australia psychology
Behavior drug effects
Divorce statistics & numerical data
Female statistics & numerical data
Genetic Variation statistics & numerical data
Humans statistics & numerical data
Male statistics & numerical data
Marital Status statistics & numerical data
Marriage statistics & numerical data
Middle Aged statistics & numerical data
Proportional Hazards Models statistics & numerical data
Reproductive Behavior drug effects
Risk Factors drug effects
Surveys and Questionnaires drug effects
Time Factors drug effects
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's
OTHERID SOURCE
NIHMS252306 NLM
PMC3066284 NLM