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| PMID |
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| TITLE |
|
| Shared aetiology of risky sexual behaviour and adolescent misconduct: genetic and environmental influences. |
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| ABSTRACT |
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| Risky sexual behaviour (RSB) is a major risk factor for serious diseases as well as unplanned pregnancy. It is not known if RSB has a genetic basis or if it is only influenced by social and cultural conditions. Adolescent conduct disorder has previously been linked to RSB and has been found to be influenced by both genetic and environmental factors. In this study, we look at normal variation in a broad measure of RSB and in retrospectively reported adolescent misconduct in a large community sample of twins (n = 4904) to partition the variance and covariance between the traits into genetic and environmental components. We found that RSB is influenced to the same extent by genes, shared environment and unshared environment. Adolescent misconduct is moderately influenced by genetic factors and only modestly by shared environmental factors. Moreover, RSB is associated with adolescent misconduct (r = 0.5), primarily because of genetic correlation between the variables. The implications of our findings as well as possible sex differences are discussed. |
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| DATE PUBLISHED |
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| HISTORY |
|
| PUBSTATUS |
PUBSTATUSDATE |
| pubmed |
2008/11/20 09:00 |
| medline |
2009/05/12 09:00 |
| entrez |
2008/11/20 09:00 |
|
| AUTHORS |
|
| NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
| Verweij KJ |
|
Verweij |
K J H |
KJ |
|
Genetic Epidemiology, Queensland Institute of Medical Research, 300 Herston Road, Brisbane, QLD 4029, Australia. karin.verweij@qimr.edu.au |
| Zietsch BP |
|
Zietsch |
B P |
BP |
|
|
| Bailey JM |
|
Bailey |
J M |
JM |
|
|
| Martin NG |
|
Martin |
N G |
NG |
|
|
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| INVESTIGATORS |
|
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| JOURNAL |
|
| VOLUME: 8 |
| ISSUE: 1 |
| TITLE: Genes, brain, and behavior |
| ISOABBREVIATION: Genes Brain Behav. |
| YEAR: 2009 |
| MONTH: Feb |
| DAY: |
| MEDLINEDATE: |
| SEASON: |
| CITEDMEDIUM: Internet |
| ISSN: 1601-183X |
| ISSNTYPE: Electronic |
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| MEDLINE JOURNAL |
|
| MEDLINETA: Genes Brain Behav |
| COUNTRY: England |
| ISSNLINKING: 1601-183X |
| NLMUNIQUEID: 101129617 |
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| PUBLICATION TYPE |
|
| PUBLICATIONTYPE TEXT |
| Journal Article |
| Research Support, N.I.H., Extramural |
| Research Support, Non-U.S. Gov't |
| Twin Study |
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| COMMENTS AND CORRECTIONS |
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| GRANTS |
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| GRANTID |
AGENCY |
COUNTRY |
| R03 MH |
NIMH NIH HHS |
United States |
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| GENERAL NOTE |
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| KEYWORDS |
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| MESH HEADINGS |
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| DESCRIPTORNAME |
QUALIFIERNAME |
| Adult |
|
| Conduct Disorder |
psychology |
| Data Interpretation, Statistical |
psychology |
| Environment |
psychology |
| Female |
psychology |
| Humans |
psychology |
| Male |
psychology |
| Middle Aged |
psychology |
| Models, Genetic |
psychology |
| Questionnaires |
psychology |
| Unsafe Sex |
statistics & numerical data |
| Young Adult |
statistics & numerical data |
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| SUPPLEMENTARY MESH |
|
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| GENE SYMBOLS |
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| CHEMICALS |
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| OTHER ID's |
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