Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
18982618
TITLE
Visualization tools for high angular resolution diffusion imaging.
ABSTRACT
There is a major effort in medical imaging to develop algorithms to extract information from DTI and HARDI, which provide detailed information on brain integrity and connectivity. As the images have recently advanced to provide extraordinarily high angular resolution and spatial detail, including an entire manifold of information at each point in the 3D images, there has been no readily available means to view the results. This impedes developments in HARDI research, which need some method to check the plausibility and validity of image processing operations on HARDI data or to appreciate data features or invariants that might serve as a basis for new directions in image segmentation, registration, and statistics. We present a set of tools to provide interactive display of HARDI data, including both a local rendering application and an off-screen renderer that works with a web-based viewer. Visualizations are presented after registration and averaging of HARDI data from 90 human subjects, revealing important details for which there would be no direct way to appreciate using conventional display of scalar images.
DATE PUBLISHED
2008
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 2008/11/06 09:00
medline 2008/12/31 09:00
entrez 2008/11/06 09:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Shattuck DW Shattuck David W DW Laboratory of Neuro Imaging, Dept. of Neurology, UCLA, Los Angeles, CA, USA.
Chiang MC Chiang Ming-Chang MC
Barysheva M Barysheva Marina M
McMahon KL McMahon Katie L KL
de Zubicaray GI de Zubicaray Greig I GI
Meredith M Meredith Matthew M
Wright MJ Wright Margaret J MJ
Toga AW Toga Arthur W AW
Thompson PM Thompson Paul M PM
INVESTIGATORS
JOURNAL
VOLUME: 11
ISSUE: Pt 2
TITLE: Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
ISOABBREVIATION: Med Image Comput Comput Assist Interv
YEAR: 2008
MONTH:
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN:
ISSNTYPE:
MEDLINE JOURNAL
MEDLINETA: Med Image Comput Comput Assist Interv
COUNTRY: Germany
ISSNLINKING: 1433-7851
NLMUNIQUEID: 101249582
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
COMMENTS AND CORRECTIONS
REFTYPE REFSOURCE REFPMID NOTE
Cites IEEE Trans Med Imaging. 2001 Nov;20(11):1131-9 11700739
Cites Magn Reson Med. 2002 Oct;48(4):577-82 12353272
Cites Magn Reson Med. 2003 Jul;50(1):175-82 12815692
Cites Neuroimage. 2004;23 Suppl 1:S208-19 15501092
Cites IEEE Trans Med Imaging. 2008 Apr;27(4):442-56 18390342
Cites J Magn Reson B. 1994 Mar;103(3):247-54 8019776
Cites Magn Reson Med. 1999 Sep;42(3):515-25 10467296
Cites Magn Reson Med. 2006 Aug;56(2):395-410 16802316
Cites Med Image Anal. 2006 Oct;10(5):764-85 16899392
Cites Radiology. 1986 Nov;161(2):401-7 3763909
GRANTS
GRANTID AGENCY COUNTRY
P41 RR013642 NCRR NIH HHS United States
P41 RR013642-10 NCRR NIH HHS United States
P41-RR013642 NCRR NIH HHS United States
R01 HD050735 NICHD NIH HHS United States
R01 HD050735-05 NICHD NIH HHS United States
R01-HD050735 NICHD NIH HHS United States
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Algorithms
Brain anatomy & histology
Diffusion Magnetic Resonance Imaging methods
Humans methods
Image Enhancement methods
Image Interpretation, Computer-Assisted methods
Reproducibility of Results methods
Sensitivity and Specificity methods
Software methods
User-Computer Interface methods
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's
OTHERID SOURCE
NIHMS284221 NLM
PMC3086333 NLM