Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
1875708
TITLE
The inheritance of alcohol consumption patterns in a general population twin sample: I. Multidimensional scaling of quantity/frequency data.
ABSTRACT
Quantity/frequency data on alcohol consumption were obtained by mailed questionnaire from 2,903 same-sex monozygotic and dizygotic Australian twin pairs. Nonmetric multidimensional scaling was applied to these data. A three-dimensional solution was required to account for the observed pattern of twin concordances for alcohol consumption. These results suggest separate determination of abstinence, frequency of consumption and quantity consumed when drinking, rather than inheritance of a single continuum of overall consumption level.
DATE PUBLISHED
1991 Jul
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 1991/07/01
medline 1991/07/01 00:01
entrez 1991/07/01 00:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Heath AC Heath A C AC Department of Human Genetics, Medical College of Virginia, Richmond 23298-0033.
Meyer J Meyer J J
Eaves LJ Eaves L J LJ
Martin NG Martin N G NG
INVESTIGATORS
JOURNAL
VOLUME: 52
ISSUE: 4
TITLE: Journal of studies on alcohol
ISOABBREVIATION: J. Stud. Alcohol
YEAR: 1991
MONTH: Jul
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0096-882X
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: J Stud Alcohol
COUNTRY: UNITED STATES
ISSNLINKING: 0096-882X
NLMUNIQUEID: 7503813
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
COMMENTS AND CORRECTIONS
GRANTS
GRANTID AGENCY COUNTRY
AA06781 NIAAA NIH HHS United States
AA07728 NIAAA NIH HHS United States
DA05588 NIDA NIH HHS United States
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adolescent
Adult
Age Factors
Aged
Alcohol Drinking psychology
Alcoholism psychology
Diseases in Twins psychology
Female psychology
Humans psychology
Male psychology
Middle Aged psychology
Models, Genetic psychology
Risk Factors psychology
Sex Factors psychology
Twins, Dizygotic psychology
Twins, Monozygotic psychology
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's