| PMID |
|
|
| TITLE |
|
| Power of the classical twin design revisited: II detection of common environmental variance. |
|
| ABSTRACT |
|
|
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| We expand our previous deterministic power calculations by calculating the required sample size to detect C in ACE models. The theoretical expected value of the maximum log-likelihood for the AE model was derived using two optimisation methods and these gave near-identical results. Theoretical predictions were verified by computer simulation and the results agreed very well. We have developed a user-friendly web-based tool, TwinPower, to perform power calculations to detect either A or C for the classical twin design. This new tool can be found at http://genepi.qimr.edu.au/cgi-bin/twinpower.cgi. |
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| DATE PUBLISHED |
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| HISTORY |
|
| PUBSTATUS |
PUBSTATUSDATE |
| pubmed |
2008/02/07 09:00 |
| medline |
2008/05/31 09:00 |
| entrez |
2008/02/07 09:00 |
|
| AUTHORS |
|
| NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
| Visscher PM |
|
Visscher |
Peter M |
PM |
|
Genetic Epidemiology, Queensland Institute of Medical Research, Brisbane, Australia. peter.visscher@qimr.edu.au |
| Gordon S |
|
Gordon |
Scott |
S |
|
|
| Neale MC |
|
Neale |
Michael C |
MC |
|
|
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| INVESTIGATORS |
|
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| JOURNAL |
|
| VOLUME: 11 |
| ISSUE: 1 |
| TITLE: Twin research and human genetics : the official journal of the International Society for Twin Studies |
| ISOABBREVIATION: Twin Res Hum Genet |
| YEAR: 2008 |
| MONTH: Feb |
| DAY: |
| MEDLINEDATE: |
| SEASON: |
| CITEDMEDIUM: Print |
| ISSN: 1832-4274 |
| ISSNTYPE: Print |
|
| MEDLINE JOURNAL |
|
| MEDLINETA: Twin Res Hum Genet |
| COUNTRY: England |
| ISSNLINKING: 1832-4274 |
| NLMUNIQUEID: 101244624 |
|
| PUBLICATION TYPE |
|
| PUBLICATIONTYPE TEXT |
| Journal Article |
| Research Support, N.I.H., Extramural |
| Research Support, Non-U.S. Gov't |
|
| COMMENTS AND CORRECTIONS |
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| REFTYPE |
REFSOURCE |
REFPMID |
NOTE |
| Cites |
Heredity (Edinb). 1978 Feb;40(1):97-116 |
272366 |
|
| Cites |
Ann Hum Genet. 2001 Nov;65(Pt 6):583-601 |
11851988 |
|
| Cites |
Twin Res Hum Genet. 2006 Aug;9(4):490-5 |
16899155 |
|
| Cites |
Behav Genet. 2006 Mar;36(2):331-40 |
16474914 |
|
| Cites |
Twin Res. 2004 Oct;7(5):505-12 |
15527666 |
|
| Cites |
Biometrics. 1994 Dec;50(4):1171-7 |
7786999 |
|
| Cites |
Behav Genet. 1994 May;24(3):239-58 |
7945154 |
|
|
| GRANTS |
|
| GRANTID |
AGENCY |
COUNTRY |
| DA-18673 |
NIDA NIH HHS |
United States |
| MH-65322 |
NIMH NIH HHS |
United States |
| R01 DA018673 |
NIDA NIH HHS |
United States |
| R01 MH065322 |
NIMH NIH HHS |
United States |
| R37 DA018673 |
NIDA NIH HHS |
United States |
|
| GENERAL NOTE |
|
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| KEYWORDS |
|
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| MESH HEADINGS |
|
| DESCRIPTORNAME |
QUALIFIERNAME |
| Computer Simulation |
|
| Environment |
|
| Likelihood Functions |
|
| Models, Theoretical |
|
| Research Design |
|
| Software |
|
| Twin Studies as Topic |
|
|
| SUPPLEMENTARY MESH |
|
|
| GENE SYMBOLS |
|
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| CHEMICALS |
|
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| OTHER ID's |
|
| OTHERID |
SOURCE |
| NIHMS570478 |
NLM |
| PMC3996914 |
NLM |
|
