Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
1821505
TITLE
Excessive follicular recruitment and growth in mothers of spontaneous dizygotic twins.
ABSTRACT
We wished to establish the frequency, regularity and laterality of multiple ovulation in mothers of dizygotic (DZ) twins and controls. Subjects had regular menses and were not using oral contraceptives. Ovarian ultrasound scans were taken over a number of cycles in 21 mothers of DZ twins and 18 controls (including 13 mothers of monozygotic [MZ] twins). Multiple large follicles (greater than or equal to 12 mm diameter) were seen significantly more frequently in mothers of DZ twins (13/21 mothers, 24/77 cycles, average +/- SE follicles/cycle 1.34 +/- 0.11) than controls (2/18 mothers, 3/31 cycles, average 1.10 +/- 0.08). Both ipsilateral and contralateral multiple follicles were observed. In one case a mother of DZ twins showed multiple large follicles in 7 out of 10 cycles in which she was scanned, including both ipsi- and contralateral patterns of occurrence.
DATE PUBLISHED
1991
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 1991/01/01
medline 1991/01/01 00:01
entrez 1991/01/01 00:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Martin NG Martin N G NG Queensland Institute of Medical Research, Brisbane, Australia.
Shanley S Shanley S S
Butt K Butt K K
Osborne J Osborne J J
O'Brien G O'Brien G G
INVESTIGATORS
JOURNAL
VOLUME: 40
ISSUE: 3-4
TITLE: Acta geneticae medicae et gemellologiae
ISOABBREVIATION: Acta Genet Med Gemellol (Roma)
YEAR: 1991
MONTH:
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0001-5660
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Acta Genet Med Gemellol (Roma)
COUNTRY: Italy
ISSNLINKING: 0001-5660
NLMUNIQUEID: 0370314
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adult
Female
Follicular Phase physiology
Humans physiology
Ovarian Follicle ultrasonography
Pregnancy ultrasonography
Pregnancy, Multiple physiology
Superovulation physiology
Twins, Dizygotic genetics
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's