Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
18020715
TITLE
A behavior genetic investigation of adolescent motherhood and offspring mental health problems.
ABSTRACT
The present study examines the relations between adolescent motherhood and children's behavior, substance use, and internalizing problems in a sample of 1,368 children of 712 female twins from Australia. Adolescent motherhood remained significantly associated with all mental health problems, even when using a quasiexperimental design capable of controlling for genetic and environmental confounds. However, the relation between adolescent motherhood and offspring behavior problems and substance use was partially confounded by family background variables that influence both generations. The results are consistent with a causal relation between adolescent motherhood and offspring mental health problems, and they highlight the usefulness of behavior genetic designs when examining putative environmental risks for the development of psychopathology. The generalizability of these results to the United States, which has a higher adolescent birth rate, is discussed.
(c) 2007 APA
DATE PUBLISHED
2007 Nov
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 2007/11/21 09:00
medline 2008/01/11 09:00
entrez 2007/11/21 09:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Harden KP Harden K Paige KP Department of Psychology, University of Virginia, Charlottesvile, VA 29904-4400, USA. kph3k@virginia.edu
Lynch SK Lynch Stacy K SK
Turkheimer E Turkheimer Eric E
Emery RE Emery Robert E RE
D'Onofrio BM D'Onofrio Brian M BM
Slutske WS Slutske Wendy S WS
Waldron MD Waldron Mary D MD
Statham DJ Statham Dixie J DJ
Martin NG Martin Nicholas G NG
INVESTIGATORS
JOURNAL
VOLUME: 116
ISSUE: 4
TITLE: Journal of abnormal psychology
ISOABBREVIATION: J Abnorm Psychol
YEAR: 2007
MONTH: Nov
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0021-843X
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: J Abnorm Psychol
COUNTRY: United States
ISSNLINKING: 0021-843X
NLMUNIQUEID: 0034461
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Twin Study
COMMENTS AND CORRECTIONS
REFTYPE REFSOURCE REFPMID NOTE
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GRANTS
GRANTID AGENCY COUNTRY
AA000264 NIAAA NIH HHS United States
AA07535 NIAAA NIH HHS United States
R01 HD053550 NICHD NIH HHS United States
R01 HD053550-01A1 NICHD NIH HHS United States
R01 HD056354 NICHD NIH HHS United States
R01 HD056354-01 NICHD NIH HHS United States
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adolescent
Adult
Child Behavior Disorders psychology
Female psychology
Humans psychology
Illegitimacy statistics & numerical data
Mental Disorders psychology
Middle Aged psychology
Models, Psychological psychology
Mother-Child Relations psychology
Pregnancy psychology
Pregnancy in Adolescence psychology
Questionnaires psychology
Twins genetics
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's
OTHERID SOURCE
NIHMS216240 NLM
PMC2903734 NLM
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Last Modified: Oct 15 2007