Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
17868128
TITLE
A comparison of early family life events amongst monozygotic twin women with lifetime anorexia nervosa, bulimia nervosa, or major depression.
ABSTRACT
OBJECTIVES NlmCategory: OBJECTIVE
To investigate the differential profile of early family life events associated with lifetime anorexia nervosa (AN), bulimia nervosa (BN), and major depression (MD).
METHOD NlmCategory: METHODS
Only data from the monozygotic twins (n = 622) were examined from a community sample of female twins who had participated in three waves of data collection. Eating disorder and MD diagnoses were ascertained from the Eating Disorder Examination at Wave 3 and interview at Wave 2 respectively. Early family events were ascertained from self-report measures at Waves 1 and 3. Two case control designs were used, including a comparison of women: (1) who had lifetime AN, BN, MD, and controls, and (2) twin pairs discordant for either AN, BN, or MD (where the unaffected cotwin formed the control group).
RESULTS NlmCategory: RESULTS
Across the two types of designs, compared to controls, both AN and BN were associated with more comments from the family about weight and shape when growing up. AN was uniquely associated with higher levels of paternal protection while BN was associated with higher levels of parental expectations.
CONCLUSION NlmCategory: CONCLUSIONS
While some overlap among early life events was indicated, especially related to parental conflict and criticism, there was evidence to support some degree of nonoverlap among life events associated with AN, BN, and MD.
(c) 2007 by Wiley Periodicals, Inc.
DATE PUBLISHED
2007 Dec
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 2007/09/18 09:00
medline 2008/03/04 09:00
entrez 2007/09/18 09:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Wade TD Wade Tracey D TD School of Psychology, Flinders University, Adelaide, South Australia, Australia. tracey.wade@flinders.edu.au
Gillespie N Gillespie Nathan N
Martin NG Martin Nicholas G NG
INVESTIGATORS
JOURNAL
VOLUME: 40
ISSUE: 8
TITLE: The International journal of eating disorders
ISOABBREVIATION: Int J Eat Disord
YEAR: 2007
MONTH: Dec
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0276-3478
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Int J Eat Disord
COUNTRY: United States
ISSNLINKING: 0276-3478
NLMUNIQUEID: 8111226
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, Non-U.S. Gov't
Twin Study
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adolescent
Adult
Age of Onset
Anorexia Nervosa psychology
Australia psychology
Bulimia Nervosa psychology
Case-Control Studies psychology
Child psychology
Comorbidity psychology
Depressive Disorder, Major psychology
Diseases in Twins psychology
Female psychology
Humans psychology
Individuality psychology
Life Change Events psychology
Parenting psychology
Personality Assessment psychology
Social Environment psychology
Twins, Monozygotic psychology
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's