Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
17328690
TITLE
Marital conflict and conduct problems in Children of Twins.
ABSTRACT
The Children-of-Twins design was used to test whether associations between marital conflict frequency and conduct problems can be replicated within the children of discordant twin pairs. A sample of 2,051 children (age 14-39 years) of 1,045 twins was used to estimate the genetic and environmental influences on marital conflict and determine whether genetic or environmental selection processes underlie the observed association between marital conflict and conduct problems. Results indicate that genetic and nonshared environmental factors influence the risk of marital conflict. Furthermore, genetic influences mediated the association between marital conflict frequency and conduct problems. These results highlight the need for quasiexperimental designs in investigations of intergenerational associations.
DATE PUBLISHED
2007 Jan-Feb
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 2007/03/03 09:00
medline 2007/05/31 09:00
entrez 2007/03/03 09:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Harden KP Harden K Paige KP Department of Psychology, University of Virginia, Charlottesville, VA 22902, USA. kph3k@virginia.edu
Turkheimer E Turkheimer Eric E
Emery RE Emery Robert E RE
D'Onofrio BM D'Onofrio Brian M BM
Slutske WS Slutske Wendy S WS
Heath AC Heath Andrew C AC
Martin NG Martin Nicholas G NG
INVESTIGATORS
JOURNAL
VOLUME: 78
ISSUE: 1
TITLE: Child development
ISOABBREVIATION: Child Dev
YEAR:
MONTH:
DAY:
MEDLINEDATE: 2007 Jan-Feb
SEASON:
CITEDMEDIUM: Print
ISSN: 0009-3920
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Child Dev
COUNTRY: United States
ISSNLINKING: 0009-3920
NLMUNIQUEID: 0372725
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Twin Study
COMMENTS AND CORRECTIONS
REFTYPE REFSOURCE REFPMID NOTE
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GRANTS
GRANTID AGENCY COUNTRY
AA000264 NIAAA NIH HHS United States
AA07535 NIAAA NIH HHS United States
R01 HD056354 NICHD NIH HHS United States
R01 HD056354-01 NICHD NIH HHS United States
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adolescent
Adult
Aged
Aged, 80 and over
Alcoholism psychology
Anxiety Disorders psychology
Child psychology
Conduct Disorder psychology
Conflict (Psychology) psychology
Depressive Disorder, Major psychology
Diseases in Twins psychology
Female psychology
Humans psychology
Male psychology
Marriage psychology
Middle Aged psychology
Models, Psychological psychology
Risk Factors psychology
Social Environment psychology
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's
OTHERID SOURCE
NIHMS243219 NLM
PMC2967412 NLM
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Last Modified: Oct 15 2007