Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
16756443
TITLE
Family structure and age at menarche: a children-of-twins approach.
ABSTRACT
Girls who grow up in households with an unrelated adult male reach menarche earlier than peers, a finding hypothesized to be an evolutionary strategy for families under stress. The authors tested the alternative hypothesis that nonrandom selection into stepfathering due to shared environmental and/or genetic predispositions creates a spurious relation between stepfathering and early menarche. Using the unique controls for genetic and shared environmental experiences offered by the children-of-twins design, the authors found that cousins discordant for stepfathering did not differ in age of menarche. Moreover, controlling for mother's age of menarche eliminated differences in menarcheal age associated with stepfathering in unrelated girls. These findings strongly suggest selection, and not causation, accounts for the relationship between stepfathering and early menarche.
((c) 2006 APA, all rights reserved).
DATE PUBLISHED
2006 May
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 2006/06/08 09:00
medline 2006/11/10 09:00
entrez 2006/06/08 09:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Mendle J Mendle Jane J Department of Psychology, University of Virginia, Charlottesville, VA 22902, USA. jm4ky@virginia.edu
Turkheimer E Turkheimer Eric E
D'Onofrio BM D'Onofrio Brian M BM
Lynch SK Lynch Stacy K SK
Emery RE Emery Robert E RE
Slutske WS Slutske Wendy S WS
Martin NG Martin Nicholas G NG
INVESTIGATORS
JOURNAL
VOLUME: 42
ISSUE: 3
TITLE: Developmental psychology
ISOABBREVIATION: Dev Psychol
YEAR: 2006
MONTH: May
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0012-1649
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Dev Psychol
COUNTRY: United States
ISSNLINKING: 0012-1649
NLMUNIQUEID: 0260564
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Twin Study
COMMENTS AND CORRECTIONS
REFTYPE REFSOURCE REFPMID NOTE
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GRANTS
GRANTID AGENCY COUNTRY
AA000264 NIAAA NIH HHS United States
AA07535 NIAAA NIH HHS United States
R01 HD056354 NICHD NIH HHS United States
R01 HD056354-01 NICHD NIH HHS United States
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adolescent
Adult
Age Factors
Child
Family
Family Characteristics
Female
Humans
Interpersonal Relations
Male
Menarche psychology
Mother-Child Relations psychology
Twins psychology
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's
OTHERID SOURCE
NIHMS243222 NLM
PMC2964498 NLM
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